Polygenic associations of neurodevelopmental genes in suicide attempt.
Stockholm, Sweden. In Mol Psychiatry, Jan 2016
Among the 590 SA polygenes implicated here, there were several developmentally important functions (cell adhesion/migration, small GTPase and receptor tyrosine kinase signaling), and 16 of the SA polygenes have previously been studied in SB (BDNF, CDH10, CDH12, CDH13, CDH9, CREB1, DLK1, DLK2, EFEMP1, FOXN3, IL2, LSAMP, NCAM1, nerve growth factor (NGF), NTRK2 and TBC1D1).
Adiponectin in asthma: implications for phenotyping.
Napoli, Italy. In Curr Protein Pept Sci, 2014
Recently, different studies demonstrated the involvement of adiponectin in asthma since its levels and the expression of AdipoR1, AdipoR2 and T-cadherin are modulated in asthma patients and in asthma mouse models.
Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis.
Atlanta, United States. In Plos One, 2014
Chlamydia induced EMT in vitro and in vivo, marked by the suppression of normal epithelial cell markers especially E-cadherin but up-regulation of mesenchymal markers of pathological EMT, including T-cadherin, MMP9, and fibronectin.
Adiponectin signaling in the liver.
Chapel Hill, United States. In Rev Endocr Metab Disord, 2014
This article reviews the adiponectin signaling pathway in the liver through T-cadherin, AdipoR1, AdipoR2, AMPK, ceramidase activity, APPL1 and the recently discovered Suppressor Of Glucose from Autophagy (SOGA).
Cardiometabolic effects of adiponectin.
Boston, United States. In Best Pract Res Clin Endocrinol Metab, 2014
T-cadherin, a GPI-anchored adiponectin-binding protein, was recently identified as critical for the cardiac-protective and revascularization actions of adiponectin.