Papers on
Cdc6
Overexpression and biological function of TMEM48 in non-small cell lung carcinoma.Lin et al., Shanghai, China. In Tumour Biol, Oct 2015
Additionally, real-time PCR and western blot analysis revealed that several cell cycle and DNA replication genes, including Cyclin B1, CDK1, CDC6, PCNA, and RCF4, were reduced after TMEM48 knockdown.
Meier-Gorlin syndrome.Bongers et al., Nijmegen, Netherlands. In Orphanet J Rare Dis, 2014
Mutations in one of five genes (ORC1, ORC4, ORC6, CDT1, and CDC6) of the pre-replication complex, involved in DNA-replication, are detected in approximately 67-78% of patients with MGS.
Genome-wide scan for selection signatures in six cattle breeds in South Africa.Maiwashe et al., South Africa. In Genet Sel Evol, 2014
In addition, a number of candidate genes associated with the nervous system (WNT5B, FMOD, PRELP, and ATP2B), immune response (CYM, CDC6, and CDK10), production (MTPN, IGFBP4, TGFB1, and AJAP1) and reproductive performance (ADIPOR2, OVOS2, and RBBP8) were also detected as being under selection.
Archaeal orc1/cdc6 proteins.Bell, Oxford, United Kingdom. In Subcell Biochem, 2011
The initiation of DNA replication in most archaeal genomes is mediated by proteins related to eukaryotic Orc1 and Cdc6.
Mechanisms and pathways of growth failure in primordial dwarfism.Jackson et al., Edinburgh, United Kingdom. In Genes Dev, 2011
Ten genes have now been identified for microcephalic primordial dwarfism, encoding proteins involved in fundamental cellular processes including genome replication (ORC1 [origin recognition complex 1], ORC4, ORC6, CDT1, and CDC6), DNA damage response (ATR [ataxia-telangiectasia and Rad3-related]), mRNA splicing (U4atac), and centrosome function (CEP152, PCNT, and CPAP).