CXCR4 and cancer.
In PLoS ONE, 2011
... (Santa Cruz, CA, USA), anti-human Rac1 from BD Pharmingen (San Jose, CA, USA) and anti-human Cdc42 antibody was obtained from Cell Signaling (Danvers, MA, USA) ... Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polaritymore suppliers
In The Journal of Cell Biology, 2007
... Antibodies against ITSN2 (Novus Biologicals), N-WASP (Santa Cruz Biotechnology, Inc.), Cdc42 (BD), pericentrin (Covance), mLGN/GPSM2/AGS3 (Abnova), α-tubulin (Sigma-Aldrich), γ-tubulin (Sigma-Aldrich), ...
Understanding gene expression in coronary artery disease through global profiling, network analysis and independent validation of key candidate genes.
Bengaluru, India. In J Genet, Dec 2015
Expression of EGR1/2/3, IL8, CXCL1, PTGS2, CD69, IFNG, FASLG, CCL4, CDC42, DDX58, NFKBID and NR4A2 genes were independently validated; EGR1/2/3 and IL8 showed >8-fold higher expression in cases relative to the controls implying their important role in CAD.
Function of Slit/Robo signaling in breast cancer.
Tianjin, China. In Front Med, Dec 2015
In addition, this pathway regulates the distant migration of breast cancer cells not only by mediating the phosphorylation of the downstream molecules of CXCL12/CXCR4 and srGAPs, such as PI3K/ Src, RAFTK/ Pyk2, and CDC42, but also by regulating the activities of MAP kinases.
A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction.
Indianapolis, United States. In Can J Physiol Pharmacol, Feb 2015
Contractile stimulation of ASM induces the recruitment and assembly of paxillin, vinculin, and focal adhesion kinase (FAK) into membrane adhesion complexes (adhesomes) that regulate actin polymerization by catalyzing the activation of cdc42 GTPase by the G-protein-coupled receptor kinase-interacting target (GIT) - p21-activated kinase (PAK) - PAK-interacting exchange factor (PIX) complex.
CDC42 Use in Viral Cell Entry Processes by RNA Viruses.
London, United Kingdom. In Viruses, 2014
The Rho family GTPase Cdc42 is appreciated as a key moderator of cellular actin dynamics, and the development of specific Cdc42-inhibiting agents has given us an unprecedented ability to investigate its individual role in signalling pathways.
Systems biology of megakaryocytes.
More papers using
Seattle, United States. In Adv Exp Med Biol, 2013
Additional signals activated by these secondary mediators include mammalian target of rapamycin; β(beta)-catenin; the G proteins Rac1, Rho, and CDC42; several transcription factors, including hypoxia-inducible factor 1α(alpha), the homeobox-containing proteins HOXB4 and HOXA9, and a number of signaling mediators that are reduced, including glycogen synthase kinase 3α(alpha) and the FOXO3 family of forkhead proteins.