Influence of zinc deficiency on Akt-Mdm2-p53 and Akt-p21 signaling axes in normal and malignant human prostate cells.more suppliers
In PLoS ONE, 2008
... (SC-509), Rb (SC-50), p21 (SC-817), p27 (SC-528), E2F1 (SC-193), CDK1 (SC-8395), Cyclin B1 (SC-595), and CDC25C (SC-13138) antibodies, together with all secondary antibodies (anti-mouse, anti-goat and anti-rabbit immunoglobulin G) were purchased from Santa Cruz Biotechnology, Inc ...
Multiple functions of the Eya phosphotyrosine phosphatase.
Chicago, United States. In Mol Cell Biol, Jan 2016
UNASSIGNED: Eyes absent (Eya), a protein conserved from plants to humans, and best characterized as a transcriptional coactivator, is also the prototype for a novel class of eukaryotic aspartyl protein tyrosine phosphatases.
Protein tyrosine phosphatases as potential therapeutic targets.
Indianapolis, United States. In Acta Pharmacol Sin, 2014
This review summarizes recent findings on several highly recognized PTP family drug targets, including PTP1B, Src homology phosphotyrosyl phosphatase 2(SHP2), lymphoid-specific tyrosine phosphatase (LYP), CD45, Fas associated phosphatase-1 (FAP-1), striatal enriched tyrosine phosphatases (STEP), mitogen-activated protein kinase/dual-specificity phosphatase 1 (MKP-1), phosphatases of regenerating liver-1 (PRL), low molecular weight PTPs (LMWPTP), and CDC25.
Embryonic onset of late replication requires Cdc25 down-regulation.
San Francisco, United States. In Genes Dev, 2012
findings suggest that high Cdc25 and Cdk1 contribute to the speed of the rapid, pre-midblastula transition (MBT) S phases and that down-regulation of these activities plays a broader role in MBT-associated changes than was previously suspected
CDC25 phosphatases in cancer cells: key players? Good targets?
More papers using
Toulouse, France. In Nat Rev Cancer, 2007
Cell division cycle 25 (CDC25) phosphatases regulate key transitions between cell cycle phases during normal cell division, and in the event of DNA damage they are key targets of the checkpoint machinery that ensures genetic stability.
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
In PLoS ONE, 1989
... Akt, p-Akt and β-actin were purchased from Cell Signaling Technology (Beverly, MA); Cyclin B1, Cdc25B, Cdc25c, Ki-67, and the secondary antibodies, which were horseradishperoxidase-conjugated, were purchased from Santa Cruz Biotechnology, Inc ...