Phage display discovery of novel molecular targets in glioblastoma-initiating cells.
Cleveland, United States. In Cell Death Differ, Aug 2014
Phage peptides bound to GICs were analyzed for their corresponding proteins and ranked based on prognostic value, identifying VAV3, a Rho guanine exchange factor involved tumor invasion, and CD97 (cluster of differentiation marker 97), an adhesion G-protein-coupled-receptor upstream of Rho, as potentially enriched in GICs.
Action and Signaling of Lysophosphatidylethanolamine in MDA-MB-231 Breast Cancer Cells.
Pusan, South Korea. In Biomol Ther (seoul), Feb 2014
Previously, we reported that lysophosphatidylethanolamine (LPE), a lyso-type metabolite of phosphatidylethanolamine, can increase intracellular Ca(2+) ([Ca(2+)]i) via type 1 lysophosphatidic acid (LPA) receptor (LPA1) and CD97, an adhesion G-protein-coupled receptor (GPCR), in MDA-MB-231 breast cancer cells.
F4/80 and the related adhesion-GPCRs.
Oxford, United Kingdom. In Eur J Immunol, 2011
F4/80 is a member of the EGF-TM7 family of leukocyte plasma membrane heptahelical molecules, which includes CD97 and EMR2.
CD97 in leukocyte trafficking.
Amsterdam, Netherlands. In Adv Exp Med Biol, 2009
CD97 is a member of the EGF-TM7 family of adhesion G protein-coupled receptors (GPCRs) broadly expressed on leukocytes.