Leukemia surfaceome analysis reveals new disease-associated features.
Zürich, Switzerland. In Blood, Jul 2013
Nine candidate markers (CD18, CD63, CD31, CD97, CD102, CD157, CD217, CD305, and CD317) were validated by flow cytometry in patient samples at diagnosis and during chemotherapy.
Microarray analyses of peripheral whole blood cells from ulcerative colitis patients: effects of leukocytapheresis.
Kurume, Japan. In Int J Mol Med, Apr 2013
After LCAP, genes with proinflammatory actions, such as CD97, CD74, human leukocyte antigen-DRβ1 and -DP light chain, were downregulated, while genes responsible for antimicrobial actions, such as neutrophil gelatinase-associated lipocalin, and acute phase reactions, such as haptoglobin α1S and α1-acid glycoprotein, were upregulated.
F4/80 and the related adhesion-GPCRs.
Oxford, United Kingdom. In Eur J Immunol, 2011
F4/80 is a member of the EGF-TM7 family of leukocyte plasma membrane heptahelical molecules, which includes CD97 and EMR2.
CD97 in leukocyte trafficking.
Amsterdam, Netherlands. In Adv Exp Med Biol, 2009
CD97 is a member of the EGF-TM7 family of adhesion G protein-coupled receptors (GPCRs) broadly expressed on leukocytes.
Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies.
Münster, Germany. In Biochim Biophys Acta, 2006
Here, DAF seems to dispose of several different functions reaching far beyond its immunological role, e.g., promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility, and metastasis via oncogenic tyrosine kinase pathway activation, and specific seven-span transmembrane receptors (CD97) binding.