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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CD72 molecule

CD72, Lyb-2
Top mentioned proteins: CD5, BCR, CD45, IgM, CD22
Papers on CD72
The role for Sema4D/CD100 as a therapeutic target for tumor microenvironments and for autoimmune, neuroimmune and bone diseases.
Ye et al., Wuhan, China. In Expert Opin Ther Targets, Feb 2016
Areas covered: The ligation of Sema4D/CD100 with CD72 on immune and inflammatory cells is known to stimulate immune responses and regulation.
Bone marrow and splenic histology in hairy cell leukaemia.
Sena Teixeira Mendes et al., London, United Kingdom. In Best Pract Res Clin Haematol, Dec 2015
The cells stain for B-cell related antigens as well as with antibodies against tartrate-resistant acid phosphatase, DBA44 (CD72), CD11c, CD25, CD103, CD123, cyclin D1 and annexin A1.
Critical role for thymic CD19+CD5+CD1dhiIL-10+ regulatory B cells in immune homeostasis.
Wang et al., Beijing, China. In J Leukoc Biol, Mar 2015
Indeed, this population was identified in the murine thymus, and furthermore, when cocultured with CD4(+) T cells, this population of B cells supported the maintenance of CD4(+)Foxp3(+) Tregs in vitro, in part, via the CD5-CD72 interaction.
CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα.
Haga et al., Suita, Japan. In Int Immunol, Feb 2015
CD72 is a transmembrane protein belonging to the C-type lectin family that is expressed by various hematopoietic cells.
Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands.
Halloran et al., Edmonton, Canada. In Am J Transplant, 2014
CD72, BTLA) and IFNG-treated macrophages (e.g.
CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection.
Jia et al., Xi'an, China. In Plos One, 2013
MATERIALS AND METHODS: We longitudinally investigated the altered expression of CD100, its receptor CD72, and other activation markers CD69 and CD86 on B cells in 20 chronic HCV-infected patients before and after treatment with pegylated interferon-alpha (Peg-IFN-α) and ribavirin (RBV) by flow cytometry.
Role of inhibitory BCR co-receptors in immunity.
Tsubata, Tokyo, Japan. In Infect Disord Drug Targets, 2012
B lymphocytes (B cells) express a variety of membrane molecules containing immunoreceptor tyrosine-based inhibition motifs (ITIMs) in the cytoplasmic region such as FcγRIIB, FCRLs, CD22, mouse Siglec-G/human Siglec-10, PECAM-1, mouse PIR-B/human LIRB1 and LIRB2PD-1 and CD72.
Placental expression of CD100, CD72 and CD45 is dysregulated in human miscarriage.
Marzioni et al., Ancona, Italy. In Plos One, 2011
CD100, CD72 and CD45 were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.
[Mast cell inhibitory receptors].
Brzezińska-Błaszczyk et al., Łódź, Poland. In Postepy Hig Med Dosw (online), 2011
The scope of this paper is to present the current knowledge on mast cell-associated inhibitory receptors, such as FcγRIIB, paired immunoglobulin-like receptor B (PIR-B), CD300, CD172a, gp49B1, CD200R, sialic acid-binding immunoglobulin-like lectin (Siglec) molecules, CD305, allergin-1, mast cell function-associated antigen (MAFA), and CD72.
Biology and function of neuroimmune semaphorins 4A and 4D.
Chapoval et al., Baltimore, United States. In Immunol Res, 2011
It is known that Sema4A has three functional receptors, namely Plexin D1, Plexin B1, and Tim-2, whereas Sema4D binds to Plexin B1 and CD72.
CD72 negatively regulates KIT-mediated responses in human mast cells.
Gilfillan et al., Bethesda, United States. In J Immunol, 2010
Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine production.
B-cell co-receptor CD72 is expressed on NK cells and inhibits IFN-gamma production but not cytotoxicity.
Takei et al., Vancouver, Canada. In Eur J Immunol, 2009
CD72 is an inhibitory receptor on NK cells regulating cytokine production.
Modulation of peripheral B cell tolerance by CD72 in a murine model.
Parnes et al., Stanford, United States. In Arthritis Rheum, 2008
CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance
CD72 polymorphism associated with child-onset of idiopathic thrombocytopenic purpura in Chinese patients.
Yang et al., Tianjin, China. In J Clin Immunol, 2008
CD72 polymorphisms are associated with age of appearing clinical manifestations in idiopathic thrombocytopenic purpura in Chinese patients.
Neuronal semaphorins regulate a primary immune response.
Catalano et al., Ancona, Italy. In Curr Neurovasc Res, 2006
By contrast, Sema4D (CD100), which is expressed on the surface of T, B and dendritic cells, increases B cell and dendritic cell function using either plexin B1 or CD72 as receptors.
Semaphorins in interactions between T cells and antigen-presenting cells.
Kumanogoh et al., Suita, Japan. In Nat Rev Immunol, 2003
SEMA4D (CD100), which is expressed constitutively by T cells, enhances the activation of B cells and dendritic cells (DCs) through its cell-surface receptor, CD72.
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.
Kikutani et al., Suita, Japan. In Nature, 2002
For example, CD100 (also known as Sema4D), a class IV transmembrane semaphorin, signals through CD72 to effect nonredundant roles in immune responses in a ligand-receptor system that is distinct from any seen previously in the nervous system.
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.
Kikutani et al., Suita, Japan. In Immunity, 2000
The class IV semaphorin CD100/Sema4D differentially utilizes two distinct receptors: plexin-B1 in nonlymphoid tissues, such as brain and kidney, and CD72 in lymphoid tissues.
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.
Kikutani et al., Suita, Japan. In Immunity, 2000
Expression cloning revealed that the CD100 receptor on lymphocytes is CD72, a negative regulator of B cell responsiveness.
CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation.
Parnes et al., Stanford, United States. In Immunity, 1999
CD72, a B cell surface protein of the C-type lectin superfamily, recruits the tyrosine phosphatase SHP-1 through its ITIM motif(s).
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