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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CD7 molecule

CD7
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD4, CD34, CD2, CD5, CD8
Papers on CD7
Residual disease detected by multidimensional flow cytometry shows prognostic significance in childhood acute myeloid leukemia with intermediate cytogenetics and negative FLT3-ITD: a report from the Tokyo Children's Cancer Study Group.
New
Ohara et al., Kawasaki, Japan. In Int J Hematol, Feb 2016
RD was evaluated by detecting the immature cells showing abnormal antigen expression pattern; CD34(+), CD15(+), CD7(+).
Primary hepatic Epstein-Barr virus-associated CD30-positive peripheral T-cell lymphoma of cytotoxic phenotype.
New
Qing et al., Torrance, United States. In Exp Mol Pathol, Feb 2016
By immunohistochemistry, the lymphoma cells expressed CD2, CD3, CD8, CD30, CD43, CD45, granzyme B, TIA-1, and negative for CD4, CD5, CD7, CD56, βF1, ALK-1, and B-cell markers.
Extranodal NK/T cell lymphoma and aggressive NK cell leukaemia: evidence for their origin on CD56+bright CD16-/+dim NK cells.
Review
New
Lima, Porto, Portugal. In Pathology, Oct 2015
The tumour NK cells usually express brightly the CD56 adhesion molecule and CD94 lectin type killer receptor, and have an activation-related (cytoplasmic CD3ε, CD7, CD45RO, HLA-DR) phenotype; in contrast, CD16 and killer immunoglobulin-like receptors are frequently negative, and CD57 expression is almost never observed.
Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues.
New
Impact
Sitnicka et al., Lund, Sweden. In Immunity, Sep 2015
Here we demonstrate that a Lin(-)CD34(+)CD38(+)CD123(-)CD45RA(+)CD7(+)CD10(+)CD127(-) population represents a NK lineage-restricted progenitor (NKP) in fetal development, umbilical cord blood, and adult tissues.
[Significance of C-myc expression in T-lymphoblastic lymphoma/leukemia and its relation with prognosis].
New
Sun et al., Taiyuan, China. In Zhonghua Bing Li Xue Za Zhi, Aug 2015
METHODS: 60 cases of T-LBL/ALL with follow-up data were studied by using immunohistochemical EnVision method for CD1a, CD3, εCD3, CD7, CD10, CD34, CD43, CD45RO, CD99, TDT, CD20, CD23, MPO, Ki-67 and C-myc.
[Human herpesvirus 8-negative primary effusion lymphoma-like lymphoma with t(8;14)(q24;q32)].
Review
New
Aiba et al., In Rinsho Ketsueki, Aug 2015
The pathological examination of the pleural effusion showed proliferation of atypical large lymphoid cells, which were positive for CD19, CD20, CD10, CD38, CD7, BCL2 and BCL6 but negative for CD5, CD30, MUM1, surface immunoglobulin, HHV-8 and EBV.
Aggressive NK-cell leukemia in a 69 years old Caucasian woman: a case report.
Munksgaard et al., Roskilde, Denmark. In Springerplus, 2014
They showed bright expression of CD56 and CD2 but markedly decreased expression of CD7.
Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma presenting in nasal cavity: a case report and review of literature.
Review
Dong et al., Chengdu, China. In Int J Clin Exp Pathol, 2014
However, they failed to express CD56, CD30, as well as mature B cells markers, such as CD79a, CD20 and T cells markers such as CD2, CD3, CD5, CD7 and CD8.
[T-cell prolymphocytic leukemia: potential diagnostic pitfalls].
Review
Maillard et al., Le Mans, France. In Ann Dermatol Venereol, 2014
Flow cytometry of peripheral blood revealed prolymphocytic T-cells staining positively for CD2, CD3, CD4 and CD7.
Successful long-term control of recurrent primary central nervous system anaplastic large cell lymphoma after autologous hematopoietic stem cell transplantation with concurrent whole brain and spinal cord radiotherapy.
Review
Kobayashi et al., Nagano, Japan. In Rinsho Ketsueki, 2014
Cerebrospinal fluid (CSF) cytology showed large atypical cells expressing CD2, cytoplasmic CD3, CD7, CD13 and CD30.
Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides.
Tunali et al., Bursa, Turkey. In J Immunol Res, 2014
Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3(+), CD4(+), CD8(+), TCRαβ (+), TCRγδ (+), CD7(+), CD4(+)CD7(+), CD4(+)CD7(-), and CD71(+)), B cells (HLA-DR(+), CD19(+), and HLA-DR(+)CD19(+)), NKT cells (CD3(+)CD16(+)CD56(+)), and NK cells (CD3(-)CD16(+)CD56(+)).
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells.
GeneRIF
Jeon et al., Ch'unch'ŏn, South Korea. In Mol Cells, 2010
low expression in T-cell lymphomas due to Twist2-mediated suppression of promoter activity; enhanced by histone deacetylase inhibitors
Frequent CD7 antigen loss in aggressive natural killer-cell leukemia: a useful diagnostic marker.
GeneRIF
Kim et al., Seoul, South Korea. In Korean J Lab Med, 2009
CD7 loss in aggressive natural killer-cell leukemia; a useful diagnostic marker
Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia.
GeneRIF
Rouhi et al., Vancouver, Canada. In Mol Cancer, 2009
These findings indicate a link between epigenetic modifications and CD7 expression in primitive chronic myeloid leukemia cells.
CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation.
GeneRIF
Quentmeier et al., Braunschweig, Germany. In J Hematol Oncol, 2009
epigenetic down-regulation of CD7 is associated with acute myeloid leukemia.
Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity.
GeneRIF
Karande et al., Bengaluru, India. In Mol Immunol, 2009
the galectin-1 glycoprotein receptor CD7 maybe a novel target for GdA on T cells.
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
Impact
Shankar et al., Boston, United States. In Cell, 2008
A CD7-specific single-chain antibody was conjugated to oligo-9-arginine peptide (scFvCD7-9R) for T cell-specific siRNA delivery in NOD/SCIDIL2rgamma-/- mice reconstituted with human lymphocytes (Hu-PBL) or CD34+ hematopoietic stem cells (Hu-HSC).
Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome.
Impact
Goff et al., London, United Kingdom. In J Clin Oncol, 2006
PATIENTS AND METHODS: Immunohistochemistry was used to study numbers and location of cells staining positive for immune cell markers CD4, CD7, CD8, CD25, CD68, forkhead box protein P3 (FOXP3), T-cell intracellular antigen-1, and Granzyme B in tissue microarrays of paraffin-embedded, diagnostic lymph node biopsies taken from 59 FL patients who lived less than 5 years (short-survival group; n = 34) and more than 15 years (long-survival group; n = 25).
Marker expression in peripheral T-cell lymphoma: a proposed clinical-pathologic prognostic score.
Impact
Pileri et al., Bologna, Italy. In J Clin Oncol, 2006
RESULTS: An aberrant phenotype with frequent loss of CD5 and/or CD7 was typical for PTCLs, irrespective of whether they were U or AILD.
Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed.
Impact
Hérait et al., Houston, United States. In J Clin Oncol, 2002
All tested patients had CD2, CD7, CD4, and/or CD8 positivity, whereas CD5 and CD3 were positive in 98% and 96% of tested patients, respectively.
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