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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Carcinoembryonic antigen-related cell adhesion molecule 8

CD66b, NCA-95, CD67, CGM6
Top mentioned proteins: CD11b, NCA, HAD, CAN, CD14
Papers using CD66b antibodies
DNA Methylation Maintains Allele-specific KIR Gene Expression in Human Natural Killer Cells
Lutz Charles T. et al., In The Journal of Experimental Medicine, 2000
... incubated with antibody complexes bispecific for erythrocyte glycophorin A and leukocytes CD3, CD4, CD19, CD36, and CD66b (RosetteSep™; StemCell Technologies Inc.) ...
Papers on CD66b
Targeting of Neutrophil Lewis X Blocks Transepithelial Migration and Increases Phagocytosis and Degranulation.
Parkos et al., Atlanta, United States. In Am J Pathol, Feb 2016
There was increased surface expression of Le(x) on PMN after TEM, and blockade of terminal Le(x) regulated post-migratory PMN functions, increasing PMN phagocytosis and the surface mobilization of azurophilic (CD63, myeloperoxidase, and neutrophil elastase) and specific (CD66b and lactoferrin) granule markers.
Comprehensive assessment of the prognosis of pancreatic cancer: peripheral blood neutrophil-lymphocyte ratio and immunohistochemical analyses of the tumour site.
Koido et al., Tokyo, Japan. In Scand J Gastroenterol, Jan 2016
The density of CD163(+ )macrophages and CD66b(+ )neutrophils was significantly higher in the high NLR group; on the contrary, the density of CD20(+ )lymphocytes was significantly higher in the low NLR group.
In vivo evidence for chylomicrons as mediators of postprandial inflammation.
Castro Cabezas et al., Rotterdam, Netherlands. In Atherosclerosis, Dec 2015
Fasting apo B48 and triglycerides correlated positively with fasting monocyte CD11b and neutrophil CD66b expression.
Intermittent Hypoxia Affects the Spontaneous Differentiation In Vitro of Human Neutrophils into Long-Lived Giant Phagocytes.
Lavie et al., Haifa, Israel. In Oxid Med Cell Longev, Dec 2015
Gϕ are CD66b(+)/CD63(+)/MPO(+)/LC3B(+) and are characterized by extended lifespan, large phagolysosomes, active phagocytosis, and reactive oxygen species (ROS) production, and autophagy largely controls their formation.
Consumption of the epidermis: a suggested precursor of ulceration associated with increased proliferation of melanoma cells.
Steiniche et al., Århus, Denmark. In Am J Dermatopathol, Nov 2015
The authors therefore performed immunohistochemical analyses of tumor cell proliferation (Melan-A/Ki67) and infiltration of inflammatory cells (CD66b neutrophils and CD163 macrophages) to better understand the biology of the epidermal changes described.
Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator.
Li et al., Guangzhou, China. In Cancer Immunol Immunother, Nov 2015
Furthermore, these ENKL-MDSCs expressed higher levels of Arg-1, iNOS and IL-17 compared to the levels of MDSCs from healthy donors, and they expressed moderate levels of TGFβ and IL-10 but lower levels of CD66b.
Using six-colour flow cytometry to analyse the activation and interaction of platelets and leukocytes--A new assay suitable for bench and bedside conditions.
Straub et al., Tübingen, Germany. In Thromb Res, Oct 2015
The morphology of platelet-leukocyte complexes (including granulocyte and monocyte content) were depicted using anti-CD45-PerCP, anti-CD66b-PE-Cy7, and anti-CD14-APC antibodies in a single sample.
Circulating apoptotic microparticles in SLE patients drive the activation of DC subsets and prime neutrophils for NETosis.
van der Vlag et al., Nijmegen, Netherlands. In Arthritis Rheumatol, Oct 2015
These microparticles were mostly CD31(+) /CD45(-) (endothelial), partially CD45(+) /CD66b(+) (granulocyte), and negative for B and T cell markers.
Differential infiltration of neutrophils in T1-T2 versus T3-T4 oral squamous cell carcinomas: a preliminary study.
de Aguiar et al., Belo Horizonte, Brazil. In Bmc Res Notes, 2014
Samples of the excised tumours were subjected to immunohistochemical analysis for CD66b and CD3.
Tumor-associated neutrophils as a new prognostic factor in cancer: a systematic review and meta-analysis.
Du et al., Jinan, China. In Plos One, 2013
I2 = 67.7%, p<0.001) for CD66b, and 1.44 (95%CI: 0.90-2.30,
High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis.
Kruse et al., Roskilde, Denmark. In Leuk Res, 2011
The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation.
(99m)Tc-Labeled murine IgM monoclonal antibody, fanolesomab, that targets the CD15 glycoprotein antigen
Chopra, Bethesda, United States. In Unknown Journal, 2011
Researchers have also evaluated several radiolabeled murine monoclonal antibodies (mAb) that target either the cluster of differentiation 67 (CD67) antigen or the CD15 antigen (e.g., anti–stage-specific embryonic antigen-1 (anti-SSEA-1), also known as fanolesomab) on neutrophils to detect infections in humans (for details, see Shanthly et al. (1)).
Myeloid derived suppressor cells in human diseases.
Korangy et al., Bethesda, United States. In Int Immunopharmacol, 2011
Interleukin 4Rα, VEGFR, CD15 and CD66b have been suggested to be more specific markers for human MDSC, however these markers can only be found on some MDSC subsets.
Targeting NCA-95 and other granulocyte antigens and receptors with radiolabeled monoclonal antibodies (Mabs).
Meller et al., Göttingen, Germany. In Q J Nucl Med Mol Imaging, 2010
During the last decade considerable effort has been made in the research for in vivo techniques of labeling neutrophils with peptides, labeled cytokines and (99m)Tc-labeled antigranulocyte monoclonal antibodies (AG-Mabs).
High expression of CEACAM6 and CEACAM8 mRNA in acute lymphoblastic leukemias.
Nomdedéu et al., Barcelona, Spain. In Ann Hematol, 2008
All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes.
CD66b regulates adhesion and activation of human eosinophils.
Kita et al., Rochester, United States. In J Immunol, 2008
CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b.
Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells.
Skubitz et al., Minneapolis, United States. In J Transl Med, 2007
Data show that desensitization of neutrophils to any two CEACAMs, 1, 3, 6, or 8, results in selective desensitization to those two CEACAMs, while the cells remain responsive to the other two neutrophil CEACAMs.
Immunological findings in patients with myelodysplastic syndrome.
Ludwig et al., Vienna, Austria. In Leuk Lymphoma, 1994
In particular, analyses of the expression density of receptors for IgG (Fc gamma Rs), complement receptors, and certain activation-associated surface molecules such as the CD67 and the M5 molecule seem to be of clinical relevance.
Radioimmunoimaging for diagnosis of bone marrow involvement in breast cancer and malignant lymphoma.
Buell et al., Germany. In Lancet, 1989
Granulopoietic bone-marrow was scintigraphically imaged in 15 patients with carcinoma of the breast and known skeletal metastases, 10 patients with malignant lymphomas, and 15 controls without suspected malignant disease, with a technetium-99m labelled murine monoclonal IgG1 antibody directed against nonspecific cross-reacting antigen (NCA-95) and carcinoembryonic antigen.
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