HNK-1 Carrier Glycoproteins Are Decreased in the Alzheimer's Disease Brain.
San Juan de Alicante, Spain. In Mol Neurobiol, Feb 2016
Decrease in HNK-1 carrier glycoproteins were not paralleled by changes in messenger RNA (mRNA) levels of the enzymes involved in the synthesis of the glycoepitope, β-1,4-galactosyltransferase (β4GalT), glucuronyltransferases GlcAT-P and GlcAT-S, or sulfotransferase HNK-1ST.
Natural killer cell maturation markers in the human liver and expansion of an NKG2C+KIR+ population.
Southampton, United Kingdom. In Lancet, Mar 2015
Mononuclear cells were isolated by ficoll separation and cell surface staining performed for CD3, CD56, CD16, CD57, CD117, CD161, CD158a, CD158b, CD49a, CD49b, CXCR6, NKG2C, and NKp46.
[Merkel cell carcinoma].
Graz, Austria. In Pathologe, 2014
chromogranin A and synaptophysin), neurofilament proteins, CD56, CD57, Bcl-2, TdT and PAX-5 are immunohistochemically positive.
CMV induces rapid NK cell maturation in HSCT recipients.
Genova, Italy. In Immunol Lett, 2013
In individuals experiencing HCMV reactivation after transplantation, NK cells rapidly achieved a fully differentiated stage of maturation, characterized by a KIR(+)NKG2A(-)NKG2C(+)CD57(+)p75/AIRM1(-) surface phenotype.
Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions.
Watford, United Kingdom. In Nat Biotechnol, 2002
Initial applications have revealed new findings, including: (i) among O-glycans in brain, a relative abundance of the Lewis(x) sequence based on N-acetyllactosamine recognized by anti-L5, and a paucity of the Lewis(x) sequence based on poly-N-acetyllactosamine recognized by anti-SSEA-1; (ii) insights into chondroitin sulfate oligosaccharides recognized by an antiserum and an antibody (CS-56) to chondroitin sulfates; and (iii) binding of the cytokine interferon-gamma (IFN-gamma) and the chemokine RANTES to sulfated sequences such as HNK-1, sulfo-Lewis(x), and sulfo-Lewis(a), in addition to glycosaminoglycans.