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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CD5 molecule

CD5, Lyt-1, Ly-1
binds CD2 glycoprotein on thymocytes; may play a role in T lymphocyte signal transduction [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CD20, CD4, HAD, CD19, CAN
Papers using CD5 antibodies
Interaction of human PD-L1 and B7-1
Supplier
Ohashi Kazuhiko et al., In Veterinary Research, 2007
... WA, USA), IL-A51 (mouse anti-bovine CD8: a gift from International Livestock Research Institute), CACT105A (mouse anti-bovine CD5: VMRD) and CAM36A (mouse anti-bovine ...
Coexistence of laryngeal squamous cell carcinoma and non-Hodgkin’s lymphoma with nasopharyngeal involvement
Supplier
Kostopoulos Ioannis et al., In Pathology Research International, 2005
... Denmark), CD45RO (clone UCHL1, DakoCytomation, Glostrup, Denmark), CD3 (clone PS1, Novocastra, Newcastle upon Tyne, UK), CD5 (clone SP19, Spring Bioscience, Inc),CD23 (clone SP23, Spring ...
Papers on CD5
Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice.
New
La Gruta et al., Melbourne, Australia. In Proc Natl Acad Sci U S A, Feb 2016
Despite finding no evidence of clonal expansions in an aged, epitope-specific TCR repertoire, nonrandom alterations in TCR usage were observed, along with elevated CD5 and CD8 coreceptor expression.
Successful Treatment With Bosentan for Digital Ulcers Related to Mixed Cryoglobulinemia: A Case Report.
New
Pinilla Llorente et al., Madrid, Spain. In Am J Ther, Feb 2016
UNASSIGNED: A 49-year-old man diagnosed with genotype 1 hepatitis C, CD5-positive marginal zone lymphoma, and mixed cryoglobulinemia type II developed skin ulcers and necrosis in his right foot.
Primary hepatic Epstein-Barr virus-associated CD30-positive peripheral T-cell lymphoma of cytotoxic phenotype.
New
Qing et al., Torrance, United States. In Exp Mol Pathol, Feb 2016
By immunohistochemistry, the lymphoma cells expressed CD2, CD3, CD8, CD30, CD43, CD45, granzyme B, TIA-1, and negative for CD4, CD5, CD7, CD56, βF1, ALK-1, and B-cell markers.
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype.
New
Khoury et al., Houston, United States. In Blood, Feb 2016
Patients with ETP-ALL/LBL were identified on the basis of the following immunophenotype: CD1a(-), CD8(-), CD5(-/dim), and positivity for one or more stem cell or myeloid antigens.
Mesenteric IL-10-producing CD5(+) regulatory B cells suppress cow's milk casein-induced allergic responses in mice.
New
Choi et al., Ch'ŏngju, South Korea. In Sci Rep, Dec 2015
We have previously demonstrated the presence of IL-10-producing CD5(+) B cells and suggested their potential role in regulating cow's milk casein allergy in humans and IgE-mediated anaphylaxis in mice.
Molecular Pathology of Adult T-Cell Leukemia/Lymphoma.
Review
New
Ohshima, Kurume, Japan. In Oncology, Nov 2015
ATLL cells express CD2, CD3, CD5, CD4, and CD25, as well as CCR4 and FoxP3 of the regulatory T-cell marker.
The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing.
Review
New
Campo et al., Pittsburgh, United States. In Virchows Arch, Nov 2015
Review of the cases contributed to the 2014 European Association for Haematopathology/Society for Hematopathology slide workshop illustrated how mutational testing has helped refine the diagnostic criteria for LPL, emphasizing the importance of identifying a clonal monotonous lymphoplasmacytic population and highlighting how LPL can still be diagnosed with extensive nodal architectural effacement, very subtle plasmacytic differentiation, follicular colonization, or uncommon phenotypes such as CD5 or CD10 expression.
[Human herpesvirus 8-negative primary effusion lymphoma-like lymphoma with t(8;14)(q24;q32)].
Review
New
Aiba et al., In Rinsho Ketsueki, Aug 2015
The pathological examination of the pleural effusion showed proliferation of atypical large lymphoid cells, which were positive for CD19, CD20, CD10, CD38, CD7, BCL2 and BCL6 but negative for CD5, CD30, MUM1, surface immunoglobulin, HHV-8 and EBV.
CD5 instructs extrathymic regulatory T cell development in response to self and tolerizing antigens.
New
Impact
Hawiger et al., Saint Louis, United States. In Immunity, Apr 2015
We report that CD5, whose expression is upregulated in T cells by self and tolerizing antigens in the thymus and periphery, governed extrathymic Treg cell development.
CD5 helps aspiring regulatory T cells ward off unwelcome cytokine advances.
New
Impact
Love et al., Bethesda, United States. In Immunity, Apr 2015
In this issue of Immunity, Henderson et al. (2015) show that CD5 regulates iTreg cell induction by rendering emerging iTreg cells refractory to signals mediated by effector-differentiating cytokines.
The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens.
Impact
Jameson et al., Minneapolis, United States. In Nat Immunol, 2015
As expression of the negative regulator CD5 correlates with self-recognition, we studied CD5(lo) and CD5(hi) naive CD8(+) T cells.
CD5 as a Target for Immune-Based Therapies.
Review
Lozano et al., Barcelona, Spain. In Crit Rev Immunol, 2014
CD5 was one of the first surface receptors described for mouse and human T lymphocytes.
Functional Heterogeneity in CD4(+) T Cell Responses Against a Bacterial Pathogen.
Review
Allen et al., Saint Louis, United States. In Front Immunol, 2014
Herein, we review our findings in this transfer system, focusing on the contribution of the immunomodulatory molecule CD5 and the importance of self-interaction in peripheral maintenance of the cell.
The pathogenesis of chronic lymphocytic leukemia.
Review
Impact
Kipps et al., San Diego, United States. In Annu Rev Pathol, 2013
Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of CD5(+)CD23(+) B cells in blood, marrow, and second lymphoid tissues.
Strategies for relapsed peripheral T-cell lymphoma: the tail that wags the curve.
Impact
Horwitz et al., New York City, United States. In J Clin Oncol, 2013
A lymph node excision confirmed relapsed angioimmunoblastic T-cell lymphoma with atypical lymphocytes expressing CD3, CD4, CD10, PD-1, and EBER, with loss of CD5 (Fig 1).
CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma: a clinicopathologic study of 14 cases.
GeneRIF
Yin et al., Houston, United States. In Hum Pathol, 2012
Our results show that CD5 expression is rare in MALT lymphoma, and is often associated with nongastric disease and an increased tendency to present with disseminated disease.
Hepatitis C virus infection of human T lymphocytes is mediated by CD5.
GeneRIF
Michalak et al., Canada. In J Virol, 2012
Hepatitis C virus infection of human T lymphocytes is mediated by CD5.
CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.
GeneRIF
van Ham et al., Amsterdam, Netherlands. In Blood, 2012
Alternative costimulation via CD5, rather than classic costimulation via CD28, primes naive T cells for stable Th17 development through promoting the expression of IL-23R.
CD5-positive marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) of the lung.
GeneRIF
Terada, Shizuoka, Japan. In Diagn Pathol, 2011
Case Report: CD5-positive marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) of the lung.
Immunologic and cytogenetic markers expressed in non-Hodgkin lymphoma of head and neck.
GeneRIF
Mogoantă et al., Bucureşti, Romania. In Rom J Morphol Embryol, 2011
Bcl-2 and CD5 are associated in non-Hodgkin lymphoma of head and neck and may be markers of poor prognosis, while Bcl-6 is positive especially in the tumor forms associated with the predominance of small cells and is a marker of favorable prognosis
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