Loss of CD47 Makes Dendritic Cells See Red.
Amsterdam, Netherlands. In Immunity, 20 Nov 2015
Cyster and colleagues now demonstrate that the "self" molecule CD47 on erythrocytes critically restricts splenic DC activation.
Current Status of Hepatocyte Xenotransplantation.
Genève, Switzerland. In Int J Surg, 08 Oct 2015
In this review we present an overview of the innate immune barriers in hepatocyte xenotransplantation, including the role of complement and natural antibodies; the role of phagocytic cells and ligands like CD47 in the regulation of phagocytic cells; and the role of Natural Killer cells.