Epigenetic Dynamics During Cd4(+) T Cells Lineage Commitment.
Oviedo, Spain. In Int J Biochem Cell Biol, 11 Jun 2015
Here we review the contribution of epigenetic mechanisms to transcriptional control during CD4 T cell differentiation and the ways in which these mechanisms interact with key transcription factors to ensure proper maturation and maintenance of cell identity.
Toxicities of Immunotherapy for the Practitioner.
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Bethesda, United States. In J Clin Oncol, 27 May 2015
The basis for the majority of these adverse events is a hyperactivated T-cell response with reactivity directed against normal tissue, resulting in the generation of high levels of CD4 T-helper cell cytokines or increased migration of cytolytic CD8 T cells within normal tissues.
Interaction of human PD-L1 and B7-1
In Veterinary Research, 2007
... Separation System (BD Biosciences, Franklin Lakes, NJ, USA) and the following antibodies: CACT138A (mouse anti-bovine CD4: VMRD, WA, USA), IL-A51 (mouse ... Cytotoxic T-cell non-Hodgkin's lymphoma of the thyroid gland
In Journal of Korean Medical Science, 2004
... by avidin-biotin-peroxidase complex methods using antibodies against CD3 (Dako, Glostrup, Denmark, prediluted), CD20 (Dako, prediluted), CD4 (Dako, prediluted), CD8 (Dako, prediluted), ... MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.
In PLoS ONE, 2003
... stained with the following antibodies, all conjugated to PE-Cy5: CD3ε (145-2C11, BioLegend, San Diego, CA), CD4 (RM4-5, eBioscience, San Diego, CA), CD8α ...