CD169-Dependent Cell-Associated HIV-1 Transmission: A Driver of Virus Dissemination.
Boston, United States. In J Infect Dis, 15 Jan 2015
We will evaluate the role of CD169 as a DC-associated HIV-1 attachment factor, investigate the molecular mechanisms by which HIV-1 particles are transferred from DCs to CD4(+) T cells across virological synapses, and provide arguments for inclusion of molecules in microbicides that can effectively target HIV-1 attachment to DCs and DC-mediated virus transfer.
Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report.
Bethesda, United States. In N Engl J Med, 26 Dec 2014
Glycoprotein-specific T-cell responses were more frequent among those who received the 2x10(11) particle-unit dose than among those who received the 2×10(10) particle-unit dose, with a CD4 response in 10 of 10 participants versus 3 of 10 participants (P=0.004) and a CD8 response in 7 of 10 participants versus 2 of 10 participants (P=0.07).
Multisite Evaluation of Point of Care CD4 Testing in Papua New Guinea.
Port Moresby, Papua New Guinea. In Plos One, Dec 2013
UNLABELLED: Laboratory-based CD4 monitoring of HIV patients presents challenges in resource limited settings (RLS) including frequent machine breakdown, poor engineering support and limited cold chain and specimen transport logistics.
NKT cell networks in the regulation of tumor immunity.
Bethesda, United States. In Front Immunol, Dec 2013
In tumor immunity, two NKT subsets (type I and type II) have contrasting roles in which they not only cross-regulate one another, but also impact innate immune cell populations, including natural killer, dendritic, and myeloid lineage cells, as well as adaptive populations, especially CD8(+) and CD4(+) T cells.
The role of drug transporters in the kidney: lessons from tenofovir.
More papers using
Liverpool, United Kingdom. In Front Pharmacol, Dec 2013
Co-morbidities (hepatitis C, diabetes), low body weight, older age, concomitant administration of potentially nephrotoxic drugs, low CD4 count, and duration of therapy are all risk factors associated with tenofovir-associated tubular dysfunction.
Interaction of human PD-L1 and B7-1
In Veterinary Research, 2007
... Separation System (BD Biosciences, Franklin Lakes, NJ, USA) and the following antibodies: CACT138A (mouse anti-bovine CD4: VMRD, WA, USA), IL-A51 (mouse ... Cytotoxic T-cell non-Hodgkin's lymphoma of the thyroid gland
In Journal of Korean Medical Science, 2004
... by avidin-biotin-peroxidase complex methods using antibodies against CD3 (Dako, Glostrup, Denmark, prediluted), CD20 (Dako, prediluted), CD4 (Dako, prediluted), CD8 (Dako, prediluted), ... MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.
In PLoS ONE, 2003
... stained with the following antibodies, all conjugated to PE-Cy5: CD3ε (145-2C11, BioLegend, San Diego, CA), CD4 (RM4-5, eBioscience, San Diego, CA), CD8α ...