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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CD36 molecule

CD36, Aquaporin 2, SR-BI, CPE, AQP2
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, V1a, Aquaporin 1
Papers using CD36 antibodies
Novel HDL-directed pharmacotherapeutic strategies
Kocher Olivier, In PLoS ONE, 2010
... The following antibodies were used: anti-SR-BI specific for the extracellular domain or the C-terminal cytoplasmic domain (Novus Biologicals, Inc., Littleton, CO), anti-glyceraldehyde-3-phosphate ...
Molecular and cellular aspects of hepatitis C virus reinfection after liver transplantation: how the early phase impacts on outcomes
McKeating Jane A. et al., In Journal of Hepatology, 2008
... anti-multi-drug resistant protein-2 (MRP-2), anti-vesicular stomatitis virus glycoprotein (VSV G) (Abcam), anti-NS5A 9E10, anti-CD81 2s131, anti-SR-BI (BD Biosciences), anti-Occludin and Claudin-1 (Invitrogen), ...
The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion.
Zernecke Alma, In PLoS ONE, 2008
... Rabbit anti-CD36 antibody was from Novus biologicals, CO, USA ...
Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I
Zlabinger Gerhard J. et al., In Cellular Immunology, 2006
... Mouse anti-human SR-BI antibodies were obtained from BD Biosciences (San Jose, CA) ...
Fasting compared with non-fasting triglycerides and risk of cardiovascular events in women.
Afarinkia Kamyar, In PLoS ONE, 2006
... functional CD36 at the surface of the cells was characterized by flow cytometry using monoclonal anti-CD36 antibody (FA6.152,
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Papers on CD36
The Effects of AS160 Modulation on Fatty Acid Transporters Expression and Lipid Profile in L6 Myotubes.
Chabowski et al., Poland. In Cell Physiol Biochem, Feb 2016
These resulted in a greater expression of fatty acid transporters, namely FABPpm and FAT/CD36, with subsequently increased FAs cellular influx.
Role of scavenger receptors in peptide-based delivery of plasmid DNA across a blood-brain barrier model.
Langel et al., Bangkok, Thailand. In Int J Pharm, Feb 2016
In this study, we prove that PF32/pDNA nanocomplexes are not only transported into brain endothelial cells via LRP-1 receptor-mediated endocytosis, but also via scavenger receptor class A and B (SCARA3, SCARA5, and SR-BI)-mediated endocytosis.
Saturated fatty acids trigger TLR4-mediated inflammatory response.
Hermsdorff et al., Viçosa, Brazil. In Atherosclerosis, Jan 2016
(2) SFAs lead to modification of gut microbiota with an overproduction of LPS after a high-fat intake, enhancing this natural TLR4 ligand.
Expression of lipases and lipid receptors in sperm storage tubules and possible role of fatty acids in sperm survival in the hen oviduct.
Yoshimura et al., Hiroshima, Japan. In Theriogenology, Jan 2016
The expression of genes encoding very low-density lipoprotein receptor(VLDLR), low-density lipoprotein receptor (LDLR), and fatty acid translocase (FAT/CD36) were found in SST cells.
Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity.
Loft et al., Copenhagen, Denmark. In Obes Rev, Jan 2016
In this review we describe a coherent mechanism of action for the development of obesity, which involves the composition of gut microbiota, HFD, low-grade inflammation, expression of fat translocase and scavenger receptor CD36, and the scavenger receptor class B type 1 (SR-BI).
Interactions Between Fatty Acid Transport Proteins, Genes that Encode for Them, and Exercise: A Systematic Review.
Rooney et al., Sydney, Australia. In J Cell Physiol, Jan 2016
Divergent data relating to acute exercise, as well as prolonged exercise training (≥3 weeks), on protein content (PC) response was identified for proteins CD36, FABPpm and CAV1.
N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Xia et al., Guangzhou, China. In J Diabetes Res, Dec 2015
Diabetes showed reduction of cardiac STAT3 activation (p-STAT3) and adiponectin with concomitantly increase of FoxO1 and CD36, which associated with reduced sevo-postC cardioprotection.
Blood-brain barrier damage in vascular dementia.
Nakagawa et al., Japan. In Neuropathology, Dec 2015
In addition, mRNA expression of osteopontin, matrix metalloproteinase-13 (MMP-13), and CD36 was increased in vessels showing BBB damage in hypertensive SHRSP.
Urine Aquaporin-2: A Promising Marker of Response to the Arginine Vasopressin Type-2 Antagonist, Tolvaptan in Patients with Congestive Heart Failure.
Kinugawa et al., Tokyo, Japan. In Int J Mol Sci, 2014
Aquaporin-2, a member of the aquaporin family, is an arginine vasopressin-regulated water channel expressed in the renal collecting duct, and a promising marker of the concentrating and diluting ability of the kidney.
Novel and conventional receptors for ghrelin, desacyl-ghrelin, and pharmacologically related compounds.
Furness et al., Melbourne, Australia. In Pharmacol Rev, 2014
None of the novel receptors, with the exception of the glycoprotein CD36, which accounts for ghrelin action at a limited number of sites, have been identified.
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Pearce et al., Saint Louis, United States. In Nat Immunol, 2014
We found that the uptake of triacylglycerol substrates via the scavenger receptor CD36 and their subsequent lipolysis by lysosomal acid lipase (LAL) was important for the engagement of elevated oxidative phosphorylation, enhanced spare respiratory capacity (SRC), prolonged survival and expression of genes that together define M2 activation.
Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2.
Marcotrigiano et al., United States. In Nature, 2014
E2 binds to the host cell through interactions with scavenger receptor class B type I (SR-BI) and CD81, and serves as a target for neutralizing antibodies.
Aquaporins: important but elusive drug targets.
Papadopoulos et al., San Francisco, United States. In Nat Rev Drug Discov, 2014
Moreover, loss-of-function mutations in human AQPs cause congenital cataracts (AQP0) and nephrogenic diabetes insipidus (AQP2), and autoantibodies against AQP4 cause the autoimmune demyelinating disease neuromyelitis optica.
Proatherogenic conditions promote autoimmune T helper 17 cell responses in vivo.
Chung et al., Houston, United States. In Immunity, 2014
Moreover, the uptake of oxLDL induced dendritic-cell-mediated Th17 cell polarization by triggering IL-6 production in a process dependent on TLR4, CD36, and MyD88.
Antioxidant Activity and Thermal Stability of Oleuropein and Related Phenolic Compounds of Olive Leaf Extract after Separation and Concentration by Salting-Out-Assisted Cloud Point Extraction.
Chatzilazarou et al., Athens, Greece. In Antioxidants (basel), 2013
A fast, clean, energy-saving, non-toxic method for the stabilization of the antioxidant activity and the improvement of the thermal stability of oleuropein and related phenolic compounds separated from olive leaf extract via salting-out-assisted cloud point extraction (CPE) was developed using Tween 80.
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
Dreux et al., Lyon, France. In J Biol Chem, 2012
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
High insulin levels are required for FAT/CD36 plasma membrane translocation and enhanced fatty acid uptake in obese Zucker rat hepatocytes.
Aspichueta et al., Leioa, Spain. In Am J Physiol Endocrinol Metab, 2012
These results suggest that the hyperinsulinemia found in animal models and patients with insulin resistance and fatty liver might contribute to liver fat accumulation by inducing FAT/CD36 functional presence at the plasma membrane of hepatocytes.
Highly upregulated expression of CD36 and MSR1 in circulating monocytes of patients with acute coronary syndromes.
Plewa et al., Poznań, Poland. In Protein J, 2012
In patients with symptoms of acute coronary syndrome the amount of CD36 and MSR1 mRNA in circulating monocytes, as well as the density of both receptors on the cells surface was significantly higher.
CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia.
Cho et al., White Plains, United States. In Ann Neurol, 2012
This study demonstrates that CD36 expressed in the periphery and brain synergize in ischemic brain injury through regulation of the MCP-1/CCR2 chemokine axis in hyperlipidemic conditions.
Inhibition of aquaporin-3 water channel in the colon induces diarrhea.
Sugiyama et al., Tokyo, Japan. In Biol Pharm Bull, 2011
The fecal water content in the colon is controlled by the transport of water from the luminal side to the vascular side, which is mediated by AQP3.
More papers using CD36 antibodies
Effect of adipocyte beta3-adrenergic receptor activation on the type 2 diabetic MKR mice
Luque Raul M., In PLoS ONE, 2005
... Hatfield, PA); oligonucleotide primers for gene expression analysis (Eurofins MWG Operon, Huntsville AL); rabbit polyclonal CD36 (H-300), rabbit polyclonal β- tubulin antibody (Santa Cruz Biotechnology, Santa Cruz, CA); TFAM ...
CD36 is a sensor of diacylglycerides.
Ojcius David, In PLoS ONE, 2004
... Anti-SR-BI (cat# NB 400-113 and NB 400-104E2) and FITC-anti-rabbit IgG (cat# NB 730-F) were purchased from Novus Biologicals (Littleton, CO) ...
Linking gene expression to function: metabolic flexibility in the normal and diseased heart
Luiken J. J. F. P. et al., In Diabetologia, 2003
... Cardiac morphology and subcellular localisation of CD36 Cardiac ventricular tissue collected in a previous study [2] was routinely embedded in paraffin (Histowax; Leica Microsystems, Wetzlar, Germany) ...
Inflammation-associated Cell Cycle–independent Block of Apoptosis by Survivin in Terminally Differentiated Neutrophils
Simon Hans-Uwe et al., In The Journal of Experimental Medicine, 2003
... FITC-conjugated anti-CD14 and anti-CD15, allophycocyanin-conjugated anti-CD34 and anti-CD11b, as well as PE-conjugated anti-CD7, anti-CD16, and anti-CD36 mAbs were obtained from Becton Dickinson and BD Biosciences ...
The syndecans, tuners of transmembrane signaling
Taylor Amanda L. et al., In The Journal of Cell Biology, 1998
... Rabbit antibody to CD36, reactive with human and mouse CD36, was from Research Diagnostics.
Metabolism of human plasma triacylglycerol-rich lipoproteins in rodent macrophages: capacity for interaction at beta-VLDL receptor
Botham Kathleen M. et al., In Biochimica et Biophysica Acta, 1984
... The blocking antibody for CD36 was obtained from Immunodiagnostic Systems Ltd (Tyne and Wear, UK) and cholesterol oxidase from Merck Biosciences Ltd (Nottingham, UK) ...
Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
Orlando Robert A et al., In Lipids in Health and Disease, 1982
... Type Culture Collection (Manassas, VA) anti-leptin polyclonal antibody was purchased from Chemicon (Temecula, CA), and anti-CD36 polyclonal antibody (H-300) was obtained from Santa Cruz Biotechnology (Santa Cruz, CA) ...
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