Shifting the Evolving CAR T Cell Platform into Higher Gear.
San Francisco, United States. In Cancer Cell, Nov 2015
In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cells to show that CD28-CD3ζ CAR T cells that constitutively express 4-1BBL promote T cell expansion and tumor eradication while reducing exhaustion.
Agonists of Co-stimulation in Cancer Immunotherapy Directed Against CD137, OX40, GITR, CD27, CD28, and ICOS.
Pamplona, Spain. In Semin Oncol, Aug 2015
Co-stimulatory receptors include surface moieties that are constitutively expressed on resting lymphocytes such as CD28 or CD27 and others whose expression is induced upon recent previous antigen priming, ie, CD137, GITR, OX40, and ICOS.
[Immunological Aspects in Oncology--Circulating γδ T Cells].
More papers using
In Klin Onkol, 2014
Detailed immunophenotyping was also conducted describing representation of memory subsets (using CD45RO and CD27 markers) and presence of surface markers HLADr, CD69, CD25, CD28, CCR7, CTLA 4, ICOS, PD 1L and PD 1 between γδ T cells of the controls and breast carcinoma patients.
GATA-3 in Human T Cell Helper Type 2 Development
In The Journal of Experimental Medicine, 1990
... anti-CD4 (Sigma-Aldrich); anti-CD19 and FITC-labeled anti–HLA-DR (DakoCytomation); PE-labeled anti–IL-4 (MP4-25D2), FITC-labeled anti–IFN-γ (4S.B3), and anti-CD28 (CD28.2;