Effects of PVA-coated nanoparticles on human T helper cell activity.
Berlin, Germany. In Toxicol Lett, 13 Feb 2016
Therefore, primary human CD4+T cells from RA patients and healthy subjects were treated with varying doses of a-PVA-SPION for 20h or 72h.T cells were then analyzed for apoptosis, cellular energy, expression of the activation marker CD25 and cell proliferation.
Endophilin marks and controls a clathrin-independent endocytic pathway.
More papers using
Cambridge, United Kingdom. In Nature, Feb 2015
This pathway mediates the ligand-triggered uptake of several G-protein-coupled receptors such as α2a- and β1-adrenergic, dopaminergic D3 and D4 receptors and muscarinic acetylcholine receptor 4, the receptor tyrosine kinases EGFR, HGFR, VEGFR, PDGFR, NGFR and IGF1R, as well as interleukin-2 receptor.