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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Fc fragment of IgE, low affinity II, receptor for

CD23, FcRgamma
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] (from NCBI)
Top mentioned proteins: CD5, CD20, IgE, CAN, HAD
Papers using CD23 antibodies
Coexistence of laryngeal squamous cell carcinoma and non-Hodgkin’s lymphoma with nasopharyngeal involvement
Kostopoulos Ioannis et al., In Pathology Research International, 2005
... Glostrup, Denmark), CD3 (clone PS1, Novocastra, Newcastle upon Tyne, UK), CD5 (clone SP19, Spring Bioscience, Inc),CD23 (clone SP23, Spring Bioscience, Inc), CD10 (clone 56C6, ...
Hodgkin lymphoma flow me?
Ibrahim Sherif et al., In CytoJournal, 2004
... or four in each tube) including CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD19, CD20, CD23, HLA-DR, and Kappa/Lambda light chain (all antibodies from Becton Dickinson, San Jose, CA) ...
Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway.
Hartl Dominik, In PLoS ONE, 1993
... Anti-CD23 peptidesp30A peptide used in this study is a synthetic linear heptapeptide (FHENWPS) obtained by panning a phage displayed peptide M13 library (Ph.D 7, New England BioLabs, Ipswich, MA, USA) on ...
Papers on CD23
Evaluation of serum markers in the LRF CLL4 trial: β2m but not serum free light chains, is an independent marker of overall survival.
Oscier et al., Bournemouth, United Kingdom. In Leuk Lymphoma, Feb 2016
The current study evaluated the prognostic significance of serum free light chains (sFLC, kappa and lambda) and other serum markers (β2M, serum thymidine kinase (sTK), soluble CD23 and LDH) together with established biomarkers in 289 patients enrolled into the LRF CLL4 trial.
Altered Peripheral B-Lymphoctye Subsets in Type 1 Diabetes and Latent Autoimmune Diabetes in Adults.
Zhou et al., Changsha, China. In Diabetes Care, Jan 2016
We determined the percentage of circulating B-lymphocyte subsets, including CD19(+)CD23(-)CD21(+) (marginal zone B [MZB]), CD19(+)CD23(+)CD21(-) (follicular B [FoB]), and CD19(+)CD5(+)CD1d(hi) (interleukin-10-producing regulatory B [B10]) cells by flow cytometry.
Extranodal follicular dendritic cell sarcoma involving tonsil.
Sulhyan et al., Pandharpur, India. In Malays J Pathol, Dec 2015
The tumour cells were immunopositive for CD21, CD23, CD35, and S-100 protein and negative for cytokeratin.
High affinity targeting of CD23 inhibits IgE synthesis in human B cells.
Vogel et al., Bern, Switzerland. In Immun Inflamm Dis, Dec 2015
The low-affinity IgE receptor FcϵRII (CD23) is part of the regulatory system controlling IgE synthesis in human B cells and exists in membrane and soluble forms.
Structure and dynamics of IgE-receptor interactions: FcεRI and CD23/FcεRII.
Davies et al., London, United Kingdom. In Immunol Rev, Nov 2015
Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII).
[Significance of C-myc expression in T-lymphoblastic lymphoma/leukemia and its relation with prognosis].
Sun et al., Taiyuan, China. In Zhonghua Bing Li Xue Za Zhi, Aug 2015
METHODS: 60 cases of T-LBL/ALL with follow-up data were studied by using immunohistochemical EnVision method for CD1a, CD3, εCD3, CD7, CD10, CD34, CD43, CD45RO, CD99, TDT, CD20, CD23, MPO, Ki-67 and C-myc.
Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia.
Wu et al., Clermont-Ferrand, France. In Blood, Aug 2015
Defining features of chronic lymphocytic leukemia (CLL) are not only its immunophenotype of CD19(+)CD5(+)CD23(+)sIgdim expressing clonal mature B cells but also its highly variable clinical course.
Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy.
Ravetch et al., New York City, United States. In Cell, Aug 2015
We show that sFcs drive BCR affinity selection by binding the Type-II FcR CD23, thus upregulating the inhibitory FcγRIIB on activated B cells.
The pathogenesis of chronic lymphocytic leukemia.
Kipps et al., San Diego, United States. In Annu Rev Pathol, 2013
Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of CD5(+)CD23(+) B cells in blood, marrow, and second lymphoid tissues.
Epstein-Barr virus positive inflammatory pseudotumor of the liver: report of a challenging case and review of the literature.
Coppola et al., Beijing, China. In Ann Clin Lab Sci, 2013
ALK1, CD21, CD23, CD35, actin, S-100, and CD34.
Antibodies as natural adjuvants.
Heyman, Uppsala, Sweden. In Curr Top Microbiol Immunol, 2013
IgE also enhances antibody and CD4(+) T cell responses to small proteins but uses the low-affinity receptor for IgE, CD23.
Clinicopathologic characteristics of inflammatory pseudotumor-like follicular dendritic cell sarcoma.
Shen et al., Ningbo, China. In Int J Clin Exp Pathol, 2013
The tumor cells expressed conventional FDC markers such as CD21 (75%), CD35 (92%), CD23 (62%), clusterin (75%), and CNA.42 (100%).
Mapping of the CD23 binding site on immunoglobulin E (IgE) and allosteric control of the IgE-Fc epsilonRI interaction.
McDonnell et al., London, United Kingdom. In J Biol Chem, 2012
CD23 and FcepsilonRI interaction sites are at opposite ends of the Cepsilon3 domain of IgE, but that receptor binding is mutually inhibitory, mediated by an allosteric mechanism
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.
Sutton et al., London, United Kingdom. In Proc Natl Acad Sci U S A, 2012
Structural comparisons with both free IgE-Fc and its FcepsilonRI complex reveal not only that the conformational changes in IgE-Fc required for CD23 binding are incompatible with FcepsilonRI binding, but also that the converse is true.
Analysis of the CD23-αv integrin interaction: a study with model peptides.
Cushley et al., Glasgow, United Kingdom. In Biochem Biophys Res Commun, 2012
Binding of sCD23-derived peptides to av integrins and their biological activities are tolerant of some substitution in the recognition motif.
Differential regulation of monocyte cytokine release by αV and β(2) integrins that bind CD23.
Cushley et al., Glasgow, United Kingdom. In Immunology, 2012
Soluble CD23 promoted the release of cytokines from the THP-1 model cell line. In both model cell lines and primary tissue, cytokine release was more pronounced in immature monocyte cells than in mature cells.
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Geha et al., Boston, United States. In Nat Immunol, 2012
In contrast, TLR9-driven expression of AICDA (which encodes the cytidine deaminase AID), the immunoglobulin receptor CD23 and the costimulatory molecule CD86 and activation of the transcription factor NF-κB, the kinase p38 and the GTPase Rac1 were intact.
Soluble CD23 controls IgE synthesis and homeostasis in human B cells.
Gould et al., London, United Kingdom. In J Immunol, 2012
mIgE & mCD21 cooperate in sCD23-mediated positive regulation of IgE synthesis on committed B cells. Feedback regulation may occur when the secreted-IgE level is big enough to allow binding to mCD23. This prevents further sCD23 release.
Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.
Iwakura et al., Tokyo, Japan. In Immunity, 2010
Dectin-2 signaling induced cytokines through an FcRgamma chain and Syk-CARD9-NF-kappaB-dependent signaling pathway without involvement of MAP kinases.
FcRgamma activation regulates inflammation-associated squamous carcinogenesis.
Coussens et al., San Francisco, United States. In Cancer Cell, 2010
Using the K14-HPV16 mouse model of squamous carcinogenesis, we report that B cells and humoral immunity foster cancer development by activating Fcgamma receptors (FcgammaRs) on resident and recruited myeloid cells.
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