Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.
Boston, United States. In Immunity, Nov 2015
Furthermore, in the absence of WIP, several receptors, namely the BCR, BAFFR, CXCR4, CXCR5, CD40, and TLR4, were impaired in promoting CD19 co-receptor activation and subsequent PI3 kinase (PI3K) signaling.
Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma.
Philadelphia, United States. In N Engl J Med, Oct 2015
A patient with refractory multiple myeloma received an infusion of CTL019 cells, a cellular therapy consisting of autologous T cells transduced with an anti-CD19 chimeric antigen receptor, after myeloablative chemotherapy (melphalan, 140 mg per square meter of body-surface area) and autologous stem-cell transplantation.
Bispecific antibodies and their applications.
Beijing, China. In J Hematol Oncol, 2014
The approval of catumaxomab (anti-EpCAM and anti-CD3) and blinatumomab (anti-CD19 and anti-CD3) has become a major milestone in the development of bsAbs.
Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides.
More papers using
Bursa, Turkey. In J Immunol Res, 2014
Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3(+), CD4(+), CD8(+), TCRαβ (+), TCRγδ (+), CD7(+), CD4(+)CD7(+), CD4(+)CD7(-), and CD71(+)), B cells (HLA-DR(+), CD19(+), and HLA-DR(+)CD19(+)), NKT cells (CD3(+)CD16(+)CD56(+)), and NK cells (CD3(-)CD16(+)CD56(+)).
IFN-g production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
In PLoS ONE, 2004
... (UCHT1, BD Biosciences), anti-CD4 (RPAT-4, BD Pharmingen), anti-CD11c (B-ly6; BD Biosciences), anti-CD14 (M5E2, BD Biosciences), anti-CD19 (HIB19, BD Biosciences), anti-CD40 (5C3, BD Biosciences), ... High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.
In PLoS ONE, 1994
... CD34, phycoerythrin (PE)-conjugated CD73, PE-conjugated CD14, PE-conjugated CD166, phycoerythrin-cyanine 5 (PC5)-conjugated Anti-HLA-DR, PC5-conjugated CD45, and PC5-conjugated CD19 (all from Becton Dickinson Biosciences, San Jose, CA, ... LIME
In The Journal of Experimental Medicine, 1993
... by flow sorting using anti–CD4-FITC (MEM-241), anti–CD8-PE (BD Biosciences), anti–CD2-PE (Immunotech), anti–CD4-biotin (Serotec), anti–CD8-biotin (Serotec), anti–CD19-biotin (Serotec), and Streptavidin-FITC (BD Biosciences) mAbs ...