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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

CD164 molecule, sialomucin

CD164, MGC-24, MGC-24v
Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008] (from NCBI)
Papers on CD164
Inhibiting CD164 expression in colon cancer cell line HCT116 leads to reduced cancer cell proliferation, mobility, and metastasis in vitro and in vivo.
GeneRIF
Li et al., Changsha, China. In Cancer Invest, 2012
CD164 is highly expressed in the colon cancer sites, and it promotes HCT116 colon cancer cell proliferation and metastasis both in vitro and in vivo
Validation of basophil CD164 upregulation for pollen allergy diagnosis.
GeneRIF
Medrala et al., Wrocław, Poland. In Arch Immunol Ther Exp (warsz), 2010
Conclude that assessment of allergen-induced basophil CD164 upregulation is a very useful method for in vitro determination of allergy to grass pollens.
Cis-regulatory functions of overlapping HIF-1alpha/E-box/AP-1-like sequences of CD164.
GeneRIF
Li et al., Changsha, China. In Bmc Mol Biol, 2010
C-jun and HIF-1alpha bound to the CD164 promoter region and activated the CD164 expression.
Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.
GeneRIF
Watt et al., In Blood, 2007
sialomucin endolyn (CD164), an adhesion receptor that regulates the adhesion of CD34+ cells to bone marrow stroma and the recruitment of CD34+CD38(lo/-) cells into cycle, associates with CXCR4
The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferation.
GeneRIF
Watt et al., Belfast, United Kingdom. In J Cell Biochem, 2007
Results demonstrate that endolyn is an evolutionarily conserved sialomucin fundamentally involved in cell proliferation in both the human and Drosophila melanogaster.
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