The evolution of natural killer cell receptors.
Utrecht, Netherlands. In Immunogenetics, Jan 2016
Thus, NKR haplotypes contain several genes encoding for receptors with activating and inhibiting signaling, and that vary in gene content and allelic polymorphism.
Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis.
Baltimore, United States. In Neurology, Jan 2016
In the high-dose group, we found a reduction in the proportion of interleukin-17(+)CD4(+) T cells (p = 0.016), CD161(+)CD4(+) T cells (p = 0.03), and effector memory CD4(+) T cells (p = 0.021) with a concomitant increase in the proportion of central memory CD4(+) T cells (p = 0.018) and naive CD4(+) T cells (p = 0.04).
Natural killer cell maturation markers in the human liver and expansion of an NKG2C+KIR+ population.
Southampton, United Kingdom. In Lancet, Mar 2015
Mononuclear cells were isolated by ficoll separation and cell surface staining performed for CD3, CD56, CD16, CD57, CD117, CD161, CD158a, CD158b, CD49a, CD49b, CXCR6, NKG2C, and NKp46.
Tc17 Cells in Immunity and Systemic Autoimmunity.
Hefei, China. In Int Rev Immunol, 2014
Current human researches have determined the significance of CD161 expression as either a marker of Tc17 cells or as an effector and regulator of Tc17 cell function.