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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Bone marrow stromal cell antigen 1

CD157, BST-1, bone marrow stromal cell antigen 1
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CD38, CAN, LRRK2, ACID, HAD
Papers on CD157
Association of Parkinson's Disease GWAS-Linked Loci with Alzheimer's Disease in Han Chinese.
New
Yu et al., Qingdao, China. In Mol Neurobiol, Feb 2016
Here, in order to discover potential AD-related loci, we investigated the association between late-onset AD (LOAD) susceptibility and nine single-nucleotide polymorphisms (SNPs) (rs11724635 of BST1, rs12637471 of MCCC1, rs15553999 of TMEM229, rs17649553 of MAPT, rs34311866 of TMEM175-GAK-DGKQ, rs356182 of SNCA, rs6430538 of ACMSD-TMEM163, rs76904798 of LRRK2 and rs823118 of RAB7L1-NUCKS1) which were reported to have genome-wide significant associations with PD risk in a recent Genome Wide Association Study performed among white population.
STK39, But Not BST1, HLA-DQB1, and SPPL2B Polymorphism, Is Associated With Han-Chinese Parkinson's Disease in Taiwan.
New
Chen et al., Dschang, Cameroon. In Medicine (baltimore), Oct 2015
including serine threonine kinase 39 (STK39) rs1955337, bone marrow stromal cell antigen 1 (BST1) rs11724635, major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1) rs9275326, and signal peptide peptidase-like 2B (SPPL2B) rs62120679, by genotyping 596 Han-Chinese patients with PD and 597 age-matched control subjects.
CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation.
New
Malavasi et al., Genova, Italy. In J Immunol, Sep 2015
CD39, CD73, and CD157 expression was higher in CD56(bright)CD16(-) than in CD56(dim)CD16(+) NK cells.
Association between bone marrow stromal cell antigen 1 gene polymorphisms and the susceptibility to Parkinson's disease: a meta-analysis.
New
Ding et al., Hangzhou, China. In Neurosci Lett, Aug 2015
A number of studies have investigated the association between Parkinson's disease (PD) and genetic polymorphisms of bone marrow stromal cell antigen 1 (BST-1).
Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche.
Review
Malavasi et al., Torino, Italy. In Ann N Y Acad Sci, 2015
Our working hypothesis, to be discussed and partially tested herein, is that CD38, and likely BST1/CD157--both NAD(+) -consuming enzymes, are active in the myeloma niche and lead a discontinuous chain of ectoenzymes whose final products are exploited by the neoplastic plasma cell as part of its local survival strategy.
Association Study between the CD157/BST1 Gene and Autism Spectrum Disorders in a Japanese Population.
Higashida et al., Kanazawa, Japan. In Brain Sci, 2014
CD157, also referred to as bone marrow stromal cell antigen-1 (BST-1), is a glycosylphosphatidylinositol-anchored molecule that promotes pre-B-cell growth.
Combination of CD157 and FLAER to Detect Peripheral Blood Eosinophils by Multiparameter Flow Cytometry.
Petrini et al., Pisa, Italy. In J Clin Exp Hematop, 2014
The combination of CD157 and FLAER was used, since FLAER recognizes all GPI-linked molecules, while CD157 is absent on the membrane of eosinophils and expressed by neutrophils.
CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion.
Review
Funaro et al., Torino, Italy. In Front Biosci, 2013
CD157 is a member of the ADP-ribosyl cyclase gene family that is involved in the metabolism of NAD.
Tracking the engraftment and regenerative capabilities of transplanted lung stem cells using fluorescent nanodiamonds.
Impact
Yu et al., Taipei, Taiwan. In Nat Nanotechnol, 2013
Here we show that fluorescent nanodiamonds, in combination with fluorescence-activated cell sorting, fluorescence lifetime imaging microscopy and immunostaining, can identify transplanted CD45(-)CD54(+)CD157(+) lung stem/progenitor cells in vivo, and track their engraftment and regenerative capabilities with single-cell resolution.
NAD⁺ metabolism: a therapeutic target for age-related metabolic disease.
Review
Auwerx et al., Lausanne, Switzerland. In Crit Rev Biochem Mol Biol, 2013
Indeed, supplying excess precursors, or blocking its utilization by poly(ADP-ribose) polymerase (PARP) enzymes or CD38/CD157, boosts NAD⁺ levels, activates sirtuins and promotes healthy aging.
CD38 and CD157: a long journey from activation markers to multifunctional molecules.
Review
Malavasi et al., Torino, Italy. In Cytometry B Clin Cytom, 2013
CD38 and its homologue CD157 (BST-1), contiguous gene duplicates on human chromosome 4 (4p15), are part of a gene family encoding products that modulate the social life of cells by means of bidirectional signals.
Lack of association between three single nucleotide polymorphisms in the PARK9, PARK15, and BST1 genes and Parkinson's disease in the northern Han Chinese population.
GeneRIF
Pang et al., Shenyang, China. In Chin Med J (engl), 2012
The SNPs investigated in the BST1, PARK15 and PARK9 genes associated with PD susceptibility are not associated with PD in the northern Han Chinese population.
Genetic variants in sporadic Parkinson's disease: East vs West.
Review
Tan et al., Singapore, Singapore. In Parkinsonism Relat Disord, 2012
Numerous GWAS linked loci including BST1 (bone marrow stromal cell antigen 1), PARK16 (parkinson disease 16 susceptibility), GAK (cyclin G associated kinase), and HLA (human leukocyte antigen) have also been identified.
Genome-wide association study confirms extant PD risk loci among the Dutch.
GeneRIF
Heutink et al., Amsterdam, Netherlands. In Eur J Hum Genet, 2011
Direct replication of single nucleotide polymorphisms (SNPs) within SNCA and BST1 confirmed these two genes to be associated with the Parkinson's Disease in the Netherlands.
The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes.
GeneRIF
Funaro et al., Torino, Italy. In J Biol Chem, 2011
The CD157-integrin partnership provides optimal adhesion and transmigration of human monocytes.
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.
Impact
Wood et al., In Lancet, 2011
Six were previously identified loci (MAPT, SNCA, HLA-DRB5, BST1, GAK and LRRK2) and five were newly identified loci (ACMSD, STK39, MCCC1/LAMP3, SYT11, and CCDC62/HIP1R).
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.
GeneRIF
French Parkinson's Disease Genetics Study Group et al., Toulouse, France. In Hum Mol Genet, 2011
found converging evidence of association with Parkinson's disease on 12q24 (rs4964469, combined P = 2.4 x 10(-7)) and confirmed the association on 4p15/BST1 (rs4698412, combined P = 1.8 x 10(-6)), previously reported in Japanese data
Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus.
GeneRIF
Liu et al., Singapore, Singapore. In Neurology, 2010
PARK16, PARK8, and PARK1 loci but not BST1 are found to be associated with Parkinson's disease.
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Impact
Toda et al., Kōbe, Japan. In Nat Genet, 2009
We identified a new susceptibility locus on 1q32 (P = 1.52 x 10(-12)) and designated this as PARK16, and we also identified BST1 on 4p15 as a second new risk locus (P = 3.94 x 10(-9)).
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology.
Review
Impact
Aydin et al., Torino, Italy. In Physiol Rev, 2008
The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of enzymes that play crucial roles in human physiology.
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