Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxegenase-2 expression predict malignant progression in oral epithelial dysplasia.
Birmingham, United Kingdom. In Br J Cancer, 07 Dec 2013
We aimed to assess the prognostic ability of six protein biomarkers linked to the epidermal growth factor receptor (EGFR) pathway, including three tetraspanins, in a large multicentre oral dysplasia cohort.Methods:One hundred and forty-eight cases with varying degrees of epithelial dysplasia underwent immunohistochemical assessment for CD9, CD151, CD82, EGFR, Her-2, and COX-2.
Diminished metastasis in tetraspanin CD151-knockout mice.
Boston, United States. In Blood, 2011
diminished metastasis in CD151-null host animals may be due to impaired tumor-endothelial interactions, with underlying defects in mouse lung endothelial cell extracellular matrix production.
Meiosis-specific RNA splicing in yeast.
New Haven, United States. In Cell, 1991
The MER2 gene is transcribed in mitosis as well as meiosis; however, the transcript is spliced efficiently to generate a functional gene product only in meiosis.