In Genome Biology, 2002
... (5 μm) were stained with hematoxylin and eosin, or subjected to immunohistochemistry with mouse monoclonal anti-CD15 (BD Biosciences, Pharmingen, Oxford, UK), mouse ...
Hodgkin Lymphoma of the Nasopharynx: Case Report with Review of the Literature.
Pittsburgh, United States. In Head Neck Pathol, Sep 2015
Immunohistochemical analysis revealed CD15, CD30, OCT-2, BOB.1, and MUM-1 expression by the neoplastic cells and a lack of expression of CD45, CD20, CD3, EMA, and EBER.
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.
Bethesda, United States. In Cell Stem Cell, 2009
Here we demonstrate that stage-specific embryonic antigen 1(SSEA-1/LeX)+ GBM cells fulfill the functional criteria for TSC/TIC, since (1) SSEA-1+ cells are highly tumorigenic in vivo, unlike SSEA-1- cells; (2) SSEA-1+ cells can give rise to both SSEA-1+ and SSEA-1- cells, thereby establishing a cellular hierarchy; and (3) SSEA-1+ cells have self-renewal and multilineage differentiation potentials.