Saturated fatty acids trigger TLR4-mediated inflammatory response.
Viçosa, Brazil. In Atherosclerosis, Jan 2016
Thus, our present review provides a new perspective on the potential mechanism by which SFAs could modulate TLR4-induced inflammatory responses: (1) SFAs can be recognized by CD14-TLR4-MD2 complex and trigger inflammatory pathways, similar to lipopolysaccharide (LPS).
The many faces of Mac-1 in autoimmune disease.
Mexico. In Immunol Rev, Jan 2016
Mac-1 (CD11b/CD18) is a β2 integrin classically regarded as a pro-inflammatory molecule because of its ability to promote phagocyte cytotoxic functions and enhance the function of several effector molecules such as FcγR, uPAR, and CD14.
Immune response gene polymorphisms in tuberculosis.
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Łódź, Poland. In Acta Biochim Pol, 2014
Strong evidence exists for genes encoding pattern recognition receptors (TLR, CD14), C-type lectins, cytokines/chemokines and their receptors (IFN-γ, TNF-α, IL-12, IL-10, MCP-1, MMP-1), major histocompatibility complex (MHC) molecules, vitamin D receptor (VDR), and proton-coupled divalent metal ion transporters (SLC11A1).
Interaction of human PD-L1 and B7-1
In Veterinary Research, 2007
... gift from International Livestock Research Institute), CACT105A (mouse anti-bovine CD5: VMRD) and CAM36A (mouse anti-bovine CD14: VMRD), respectively ... IFN-g production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
In PLoS ONE, 2004
... eBioscience), mouse IgG: anti-CD3 (UCHT1, BD Biosciences), anti-CD4 (RPAT-4, BD Pharmingen), anti-CD11c (B-ly6; BD Biosciences), anti-CD14 (M5E2, BD Biosciences), anti-CD19 (HIB19, BD Biosciences), ... C1q deficiencies and C1q in autoimmunity
In The Journal of Experimental Medicine, 1997
... mAbs to Fas (CH11), CD14, and a polyclonal sheep antiserum to FH were purchased from Upstate Biotechnology, Jackson ImmunoResearch Laboratories, and The Binding Site, respectively ... Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow
In PLoS ONE, 1996
... (FITC) (BD Biosciences Pharmingen, Franklin Lake, NJ, USA), CD45 FITC (Caltag Laboratories, Burlingame, CA, USA), CD14 phycoerytrin (PE) (BD Biosciences Pharmingen), CD90 PE (BD ... LIME
In The Journal of Experimental Medicine, 1993
... flow cytometer (Becton Dickinson) and PE-conjugated mAbs to CD3 and CD19 (Serotec), biotinylated anti-CD14 (Serotec), fluoresceinylated (FITC) streptavidin (BD Biosciences), unlabeled CD56 mAb MEM-188, ... Non–T Cell Activation Linker (NTAL)
In The Journal of Experimental Medicine, 1980
... FACS Vantage™ flow cytometer (Becton Dickinson) and PE-conjugated mAbs to CD3 and CD19 (Serotec), biotinylated anti-CD14 (Serotec), fluoresceinated streptavidin (BD Biosciences), unlabeled CD56 mAb MEM-188 ...