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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Chaperonin containing Tcp1, subunit 8

CCT8, CCTtheta, Cct8p, Cctq
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Top mentioned proteins: TRIC, CAN, CCTG, CCT5, CCT2
Papers on CCT8
Identification of the T-complex protein as a binding partner for newly synthesized cytoplasmic dynein intermediate chain 2.
New
Catling et al., New Orleans, United States. In Biochem Biophys Res Commun, Feb 2016
We confirmed interactions between IC-2 and CCT5 and CCT8 in co-immunoprecipitation experiments and determined that the C-terminal half of IC-2 is necessary and sufficient to bind CCT8.
Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma.
New
Chang et al., Taipei, Taiwan. In Tumour Biol, Jan 2016
Furthermore, our findings indicated that GRP94 knockdown might attenuate HCC cell metastasis by inhibiting CCT8/c-Jun/EMT signaling.
Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in glioma.
New
Wang et al., Nantong, China. In Pathol Res Pract, Oct 2015
However, little is known about the expression of t-complex protein subunits TCP1theta (CCT8) in gliomas.
Up-Regulation of CCT8 Related to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats.
New
Liu et al., Yancheng, China. In Neurochem Res, Sep 2015
In this study, we identified that the chaperonin containing TCP-1, subunit 8 (CCT8), as a member of class II chaperonins, was significantly upregulated following TBI.
Chaperonin containing TCP1, subunit 8 (CCT8) is upregulated in hepatocellular carcinoma and promotes HCC proliferation.
Zhang et al., Nantong, China. In Apmis, 2014
In this study, we investigated a possible involvement of CCT subunit 8 (CCT8) in HCC development.
Molecular determinants of the ATP hydrolysis asymmetry of the CCT chaperonin complex.
Valpuesta et al., Madrid, Spain. In Proteins, 2014
We have found that most of these SDPs are located near the ATP binding site, and that they define four CCT clusters, corresponding to subunits CCT3, CCT6, CCT8 and CCT1/2/4/5/7.
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT.
Takashiba et al., Okayama, Japan. In Pathog Dis, 2013
In comparison with healthy controls, periodontitis patients showed significantly higher responses to CCT4 and CCT8 on dot blot analysis.
Expression of trisomic proteins in Down syndrome model systems.
Gardiner et al., Aurora, United States. In Gene, 2013
Twelve proteins had detectable expression in LCLs and three, CCT8, MX1 and PWP2, showed elevated levels in LCLs derived from patients with DS compared with controls.
The chaperonin CCT8 facilitates spread of tobamovirus infection.
Kragler et al., Vienna, Austria. In Plant Signal Behav, 2012
In a mutant screen for KN1 transport deficiency, a component of a type II chaperonin complex, CCT8, was identified, and found to interact with non-cell-autonomous proteins.
Association of CRISP2, CCT8, PEBP1 mRNA abundance in sperm and sire conception rate in Holstein bulls.
Kasimanickam et al., Pullman, United States. In Theriogenology, 2011
The objective was to determine the association of mRNA expression of cystine rich secretary protein 2 (CRISP2), chaperonin containing T-complex protein 1, subunit 8 (CCT8), and phosphatidylethanolamine-binding protein 1 (PEBP1), in sperm of Holstein bulls with Sire Conception Rate (SCR) scores between -4 and +4.
Antigenic group II chaperonin in Methanobrevibacter oralis may cross-react with human chaperonin CCT.
Takashiba et al., Okayama, Japan. In Mol Oral Microbiol, 2010
Western immunoblotting using antiserum against human CCT subunits indicated that anti-CCT3 and anti-CCT8 antibodies recognized recombinant Cpn-1.
Proteomic comparison of detergent-extracted sperm proteins from bulls with different fertility indexes.
Sullivan et al., Québec, Canada. In Reproduction, 2010
T-complex protein 1 subunits epsilon and (CCT5 and CCT8), two isoforms of epididymal sperm-binding protein E12 (ELSPBP1), proteasome subunit alpha type-6 and binder of sperm 1 (BSP1) were more expressed in the LF group than in the HF group.
Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes.
Brocchieri et al., Gainesville, United States. In Bmc Evol Biol, 2009
Comparative analyses from several vertebrate genomes established the monophyletic origin of chaperonin-like MKKS and BBS genes from the CCT8 lineage.
Nicotine response genetics in the zebrafish.
Ekker et al., Minneapolis, United States. In Proc Natl Acad Sci U S A, 2009
We used this method to molecularly characterize bdav/cct8 and hbog/gabbr1.2
Transcriptional regulation of the cytosolic chaperonin theta subunit gene, Cctq, by Ets domain transcription factors Elk-1, Sap-1a, and Net in the absence of serum response factor.
GeneRIF
Nagata et al., Kyoto, Japan. In J Biol Chem, 2003
transcription of the Cctq gene is regulated by TCFs under the control of the Ras/MAPK pathway, probably independently of serum response factor.
Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts.
Review
Sherman et al., Düsseldorf, Germany. In Yeast, 1996
Cct8p from C. albicans, the only other completely sequenced Cct protein from a fungal species other than S. cerevisiae, is 72% and 61% similar to the S. cerevisiae and mouse Cct8 proteins, respectively.
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