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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 30 Mar 2015.

CCKBR cholecystokinin B receptor

CCK-B receptor
Top mentioned proteins: Cholecystokinin, Gastrin, ACID, HAD, CCK-4
Papers using CCK-B receptor antibodies
The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
Železná Blanka et al., In BMC Neuroscience, 1981
... , NeoMPS, Strasbourg, France), CCK-A receptor antagonist devazepide (L364,718) or CCK-B receptor antagonist L365,260 (gift from ML Laboratories, Liverpool, UK) and CART(61-102) (Bachem, Bubendorf, Switzerland) were used ...
Papers on CCK-B receptor
Distribution of cholecystokinin-B receptor genotype between patients with pancreatic cancer and controls and its impact on survival.
Frazier et al., Pittsburgh, United States. In Pancreas, 31 Mar 2015
OBJECTIVE: Cholecystokinin (CCK) and gastrin stimulate growth of pancreatic cancer through the CCK-B receptor (CCK-BR).
Investigation of cholecystokinin receptors in the human lower esophageal sphincter.
Drew et al., Shijiazhuang, China. In World J Gastroenterol, Jul 2014
Western blot was used to measure CCK-A and CCK-B receptor subtypes in the two muscles.
Synthesis, analytical analysis, and medicinal aspect of novel benzimidazoles and their metal complexes.
Sharma et al., In Chem Biol Drug Des, 2013
Benzimidazole and their metal analogs that can act as multimodal agent and have non-peptidic CCK-B receptor antagonist were synthesized and characterized on the basis of spectroscopic techniques such as FT-IR, NMR, FAB-MS and also evaluated for biologic efficacy.
Characterization of gastrins and their receptor in solid human gastric adenocarcinomas.
Rehfeld et al., Copenhagen, Denmark. In Scand J Gastroenterol, 2013
OBJECTIVE: The gastrin and the gastrin/CCK-B receptor genes are co-expressed in several carcinomas.
Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity.
Rakovska et al., Sofia, Bulgaria. In Brain Res Bull, 2013
CAM 1028 (10μM), a CCK-B receptor antagonist, also prevented the potentiating effect of CCK-8 (0.01μM) on electrically stimulated release of [(3)H]ACh.
Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis.
Smith et al., United States. In Am J Physiol Gastrointest Liver Physiol, 2012
Gastrin stimulates the growth of pancreatic cancer cells through the activation of the cholecystokinin-B receptor (CCK-BR), which has been found to be overexpressed in pancreatic cancer.
CCK-B receptor gene and response to cholecystokinin-tetrapeptide in healthy volunteers.
Bradwejn et al., Ottawa, Canada. In Peptides, 2012
Given the potential role of the central cholecystokinin receptor (CCKBR) (CT) polymorphism alleles 26 and 27 in PD, the present study attempted to discern if these alleles moderated panicogenic sensitivity to the CCKBR agonist, CCK-tetrapeptide (CCK-4), in healthy volunteers.
Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: cholecystokinin and gastrin peptides.
Rehfeld, Copenhagen, Denmark. In Acta Physiol (oxf), 2011
For instance, foetal and neonatal islets express significant amounts of gastrin, and human as well as porcine islet cells express the gastrin/CCK-B receptor abundantly.
Gastrin stimulates the VEGF-A promotor in a human colon cancer cell line.
Schmitz et al., Bochum, Germany. In Regul Pept, 2011
Therefore, CCK-B receptor antagonists may represent a treatment strategy in patients with colorectal cancer.
Cholecystokinin-8 antagonizes electroacupuncture analgesia through its B receptor in the caudate nucleus.
Xu et al., Harbin, China. In Neuromodulation, 2010
The present study examined the antagonistic effects of the intracerebral ventricular injection of CCK-8 on EA analgesia and reversing effects of CCK-B receptor antagonist (L-365,260) injection into the caudate nucleus on CCK-8.
The biology of cholecystokinin and gastrin peptides.
Hansen et al., Copenhagen, Denmark. In Curr Top Med Chem, 2006
Cholecystokinin (CCK) and gastrin together constitute a family of homologous peptide hormones, which are both physiological ligands for the gastrin/CCK-B receptor, whereas the CCK-A receptor binds only sulfated CCK-peptides.
Peptide receptor radionuclide therapy.
De Jong et al., Rotterdam, Netherlands. In Ann N Y Acad Sci, 2004
For PRRT of CCK-B receptor-positive tumors, such as medullary thyroid carcinoma, radiolabeled minigastrin analogues currently are being successfully applied.
Cholecystokinin: possible mediator of fever and hypothermia.
Pétervári et al., Pécs, Hungary. In Front Biosci, 2004
Central microinjection of CCK in rats induces a thermogenic response that can be attenuated by CCK-B receptor antagonists, but some authors observed a hypothermia.
Radiolabeling approaches for cholecystokinin B receptor imaging.
Salvatore et al., Napoli, Italy. In Biopolymers, 2001
In particular, cholecystokinin (CCK) receptors of the subtype B (CCK-BR) have been shown to be overexpressed in certain neuroendocrine tumors including medullary thyroid cancer.
Central inhibitory dysfunctions: mechanisms and clinical implications.
Xu et al., Huddinge, Sweden. In Behav Brain Sci, 1997
Furthermore, CI 988, an antagonist of the CCK-B receptor, chronically coadministered with morphine, reduces autotomy, a behavior that may be a sign of neuropathic pain following peripheral nerve section.
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