Protease-activated receptor 4: a critical participator in inflammatory response.
Zhengzhou, China. In Inflammation, Apr 2015
The biological effect of PARs activated by coagulation proteases to regulate hemostasis and thrombosis plays an enormous role in the cardiovascular system, while PAR4 can also be activated by trypsin, cathepsin G, the activated factor X of the coagulation cascade, and trypsin IV.
Pathologic manifestations of levamisole-adulterated cocaine exposure.
San Francisco, United States. In Diagn Pathol, 2014
This discrepancy is due to the fact that p-ANCA seen in association with levamisole-adulterated cocaine exposure is often directed against atypical p-ANCA-associated antigens within the neutrophil granules such as human neutrophil elastase, lactoferrin, and cathepsin G. Biopsies of the skin lesions reveal leukocytoclastic vasculitis often involving both superficial and deep dermal vessels.
Physiopathologic mechanisms involved in mare endometrosis.
Lisbon, Portugal. In Reprod Domest Anim, 2014
A long-term in vitro exposure of mare endometrium explants to NETs components (myeloperoxidase, elastase and cathepsin G) up-regulated fibrosis markers TGFβ and Tissue inhibitor of metalloproteinase (TIMP-1).