Cathepsin D: a cellular roadmapmore suppliers
In The Journal of Cell Biology, 2007
... monoclonal anti–β-actin were obtained from Sigma-Aldrich, sheep anti–human TGN46 were obtained from AbD Serotec, monoclonal anti–cathepsin D antibody was obtained from Cell Signaling Technology, and anti-Cab45 monoclonal ...
Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury.
Göteborg, Sweden. In Autophagy, Feb 2016
Moreover, we investigated the lentiform nucleus of human newborns who died after severe perinatal asphyxia and found increased neuronal autophagy after severe hypoxic-ischemic encephalopathy compared to control uninjured brains, as indicated by the numbers of MAP1LC3B/LC3B (microtubule-associated protein 1 light chain 3)-, LAMP1 (lysosomal-associated membrane protein 1)-, and CTSD (cathepsin D)-positive cells.
Cell biology of the NCL proteins: What they do and don't do.
Sioux Falls, United States. In Biochim Biophys Acta, Oct 2015
Some of them such as CLN1 (palmitoyl protein thioesterase 1), CLN2 (tripeptidyl-peptidase 1), CLN5, CLN10 (cathepsin D), and CLN13 (cathepsin F), are lysosomal soluble proteins; others like CLN3, CLN7, and CLN12, have been proposed to be lysosomal transmembrane proteins.
The Role of Retromer in Alzheimer's Disease.
Qingdao, China. In Mol Neurobiol, Aug 2015
Retromer dysfunction may result in decreasing the clearance of extracellular tau and the level of cathepsin D, which enables tau-induced neurotoxicity.
Breast cancer statistics and markers.
More papers using
Guntūr, India. In J Cancer Res Ther, 2014
Here, the review is been focused on different breast cancer markers, that is, tissue markers (hormone receptors, human epidermal growth factor-2, urokinase plasminogen activator, plasminogen activator inhibitor, p53 and cathepsin D), genetic markers (BRAC1 and 2 and gene expression microarray technique, etc.), and serum markers (CA 15.3, BR 27.29, MCA, CA 549, carcinoembryonic antigen, oncoproteins, and cytokeratins) used in present diagnosis, but none of the mentioned markers can diagnose breast cancer at an early stage.