Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.
Richmond, United States. In Mol Psychiatry, 2011
In addition, SNPs in Ankyrin Repeat and Sterile Alpha Motif Domain-Containing Protein 1B (ANKS1B) and in the Contactin-Associated Protein-Like 5 gene (CNTNAP5), which mediated the effects of olanzapine and risperidone on Negative symptoms, were very close to our threshold for declaring significance.
Changes in whole blood gene expression in obese subjects with type 2 diabetes following bariatric surgery: a pilot study.
Cleveland, United States. In Plos One, 2010
Among the significantly regulated genes were GGT1, CAMP, DEFA1, LCN2, TP53, PDSS1, OLR1, CNTNAP5, DHCR24, HHAT and SARDH, which have been previously implicated in lipid metabolism, obesity and/or type 2 diabetes.