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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Caspase 3, apoptosis-related cysteine peptidase

Caspase 3
Top mentioned proteins: PrP, caspase-3, bcl-2, Bax, V1a
Papers using Caspase 3 antibodies
The novel phloroglucinol derivative BFP induces apoptosis of glioma cancer through reactive oxygen species and endoplasmic reticulum stress pathways
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Lu Dah-Yuu et al., In International Journal of Molecular Sciences, 2011
... Primary antibodies against cleaved caspase 3, and phosphorylation of eIF2α were purchased from Cell Signaling and Neuroscience (Danvers, MA, ...
The projected effect of risk factor reduction on Alzheimer's disease prevalence.
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Ginsberg Stephen D., In PLoS ONE, 2010
... antibodies against phosphorylated ERK (P44/42), total ERK, phosphorylated JNK (Thr183 or Tyr185), total JNK, cleaved caspase-3, phosphorylated GSK-3β (Ser9) and mouse monoclonal antibody against synapsin-1 were from Cell Signaling Technology (Boston, MA, USA) ...
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-{kappa}B and activation of caspase-8
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Vanden Berghe T et al., In Cell Death & Disease, 2010
... USA); anti-RIP3 (R4277, Sigma Aldrich); rabbit polyclonal antibody against full-length murine caspase-3 (made in-house); cleaved caspase-3 antibody (9661; Cell Signaling Technology, Danvers, MA, USA) ...
The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer
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Wang Guang-Yi et al., In International Journal of Medical Sciences, 2009
... was purchased from Santa Cruz (Santa Cruz, CA), mTOR, phosphorylated p-mTOR (Ser 2448), and cleaved caspase 3 (p17) antibodies were from Cell Signaling (Beverly, MA) ...
Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis.
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Mayer Claudine, In PLoS ONE, 2009
... Anti-caspase-3 antibody was purchased from Cell Signaling Technology and anti-actin antibody ...
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Papers on Caspase 3
Autophagy in granular corneal dystrophy type 2.
Review
New
Kim et al., Seoul, South Korea. In Exp Eye Res, Mar 2016
Furthermore, inhibition of autophagy induces cell death of GCD2 corneal fibroblasts through active caspase-3.
Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling.
Review
New
Awasthi et al., Duarte, United States. In Toxicol Appl Pharmacol, Jan 2016
We demonstrate that 4HNE induced apoptosis in various cell lines is accompanied with c-Jun-N-terminal kinase (JNK) and caspase-3 activation.
Treatment of chronic kidney disease using a traditional Chinese medicine, Flos Abelmoschus manihot (Linnaeus) Medicus (Malvaceae).
Review
New
Chen et al., Beijing, China. In Clin Exp Pharmacol Physiol, Jan 2016
The renoprotective effects of Flos A. manihot are related to inhibition of caspase-3 and caspase-8 overexpression, reduction of the infiltration of ED1+ and ED3+ macrophages, downregulation of oxidative stress, inhibition of the p38 mitogen-activated protein kinase and serine/threonine kinase pathways and suppression of transforming growth factor-β1 and tumour necrosis factor-α expression.
Functional mechanism of the enhancement of 5-fluorouracil sensitivity by TUSC4 in colon cancer cells.
New
Liu et al., Harbin, China. In Oncol Lett, Dec 2015
Furthermore, 5-FU upregulated caspase-3 and caspase-9, promoting apoptosis in TUSC4-overexpressing cells compared with cells that were transduced with TUSC4 or treated with 5-FU and NC cells.
Factors affecting platinum sensitivity in cervical cancer.
New
Fukasawa et al., Tokyo, Japan. In Oncol Lett, Dec 2015
Each specimen was assessed for immunohistochemical expression of Ki-67, p53, B-cell lymphoma-2 (Bcl-2), Bcl-2-associated X protein (Bax), cleaved caspase-3, cyclooxygenase-2 (COX-2), and excision repair cross-complementation group 1 (ERCC1).
Green Tea Polyphenols Attenuated Glutamate Excitotoxicity via Antioxidative and Antiapoptotic Pathway in the Primary Cultured Cortical Neurons.
New
Qin et al., Beijing, China. In Oxid Med Cell Longev, Dec 2015
Furthermore, our results demonstrated that green tea polyphenols restored the dysfunction of mitochondrial pro- or antiapoptotic proteins Bax, Bcl-2, and caspase-3 caused by glutamate.
Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1.
New
Yu et al., Xi'an, China. In Oxid Med Cell Longev, Dec 2015
BBR conferred cardioprotective effects by improving postischemic cardiac function, decreasing infarct size, reducing apoptotic index, diminishing serum creatine kinase and lactate dehydrogenase levels, upregulating SIRT1, Bcl-2 expressions, and downregulating Bax and caspase-3 expressions.
2',4'-dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC-3 human prostate cancer cell growth by induction of apoptosis.
New
Li et al., Zhenjiang, China. In Oncol Lett, Dec 2015
The results demonstrated that the induction of apoptosis is associated with cell cycle arrest at the G0/G1 phase and activation of caspase-3/-7.
Interaction between HSP 70 and iNOS in skeletal muscle injury and repair.
Review
New
Kim, Ulsan, South Korea. In J Exerc Rehabil, Oct 2015
In conclusion, the inhibition of HSP 70 on caspase-3 and apoptosis is associated with its inhibition on iNOS that leads to less NO production.
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Impact
Kile et al., Australia. In Cell, 2015
Pharmacological caspase inhibition or genetic deletion of caspase-9, Apaf-1, or caspase-3/7 causes dying cells to secrete IFN-β.
Role of Monocarboxylate Transporter in Statin-induced Cytotoxicity.
Review
Kobayashi, Japan. In Yakugaku Zasshi, 2014
Statin-induced cytotoxicity was associated with intracellular acidification and caspase-3/7 activation.
HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.
Impact
Courtois et al., Paris, France. In Nature, 2014
We have previously demonstrated that normal human erythroid maturation requires a transient activation of caspase-3 at the later stages of maturation.
Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo.
Impact
Rao et al., Stanford, United States. In Nat Chem, 2014
Here we employ an optimized first-order bioorthogonal cyclization reaction to control the self-assembly of a fluorescent small molecule, and demonstrate its in vivo applicability by imaging caspase-3/7 activity in human tumour xenograft mouse models of chemotherapy.
Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency.
Impact
Ruohola-Baker et al., Seattle, United States. In Cell Stem Cell, 2014
TRAIL inhibits induced pluripotent stem cell (iPSC) generation by repressing apoptotic caspase 3 activity specifically in cells undergoing reprogramming but not human embryonic stem cells (hESCs), and inhibiting TRAIL activity enhances human iPSC generation.
A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.
Impact
van Lookeren Campagne et al., San Francisco, United States. In Nature, 2014
In turn, deletion of the caspase-3-encoding gene, Casp3, or elimination of the caspase cleavage site by site-directed mutagenesis rescued starvation-induced autophagy and pathogen clearance, respectively.
Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation.
GeneRIF
Durand et al., Paris, France. In Proc Natl Acad Sci U S A, 2011
in the developing diencephalon, Caspase3 acts downstream of Barhl2 in limiting neuroepithelial cell proliferation by inhibiting beta-catenin activation.
PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.
GeneRIF
Yang et al., Columbus, United States. In J Biol Chem, 2010
PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.
More papers using Caspase 3 antibodies
ER-alpha36, a Novel Variant of ER-alpha, Mediates Estrogen-Stimulated Proliferation of Endometrial Carcinoma Cells via the PKCdelta/ERK Pathway.
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Aziz Syed, In PLoS ONE, 2009
... Antibody for cleaved caspase-3 was purchased from Cell Signaling (Beverly, MA) ...
Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease
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Ko Seong-Gyu et al., In Journal of Biomedical Science, 2009
... COX-2, iNOS, bcl2, bax, procaspase-3, cleaved caspase-3, 8 and 9, and peroxidase-conjugated secondary antibody were purchased from Santa Cruz Biotechnology (CA, USA).
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining.
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Song Libing, In PLoS ONE, 2009
... anti-Ku70 (A-9) and anti-Bax (N-20) IgGs were from Santa Cruz Biotechnology (Santa Cruz, CA); anti-cleaved caspase-3 and anti-cleaved PARP IgGs were from Cell Signaling Technology (Danvers, MA); horseradish ...
Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme*
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Martin Seamus J. et al., In The Journal of Biological Chemistry, 2008
... Anti-active caspase-3 and anti-PAK2 were purchased from Cell Signaling (catalog nos ...
Sarcophine-diol, a chemopreventive agent of skin cancer, inhibits cell growth and induces apoptosis through extrinsic pathway in human epidermoid carcinoma A431 cells
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Dwivedi Chandradhar et al., In Marine Drugs, 2008
... Primary antibody against cleaved caspase-3 was purchased from Cell Signaling Technology, Inc., (Beverly, MA, ...
Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential
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Chen Buxing et al., In International Journal of Molecular Sciences, 2008
... Anti-cytochrome c, -COXIV, -Bax, -BCL-2, and -cleaved caspase-3 antibodies were from Cell Signaling Technology (Danvers, MA, USA) ...
Role of hydrogen peroxide in NF-kappaB activation: from inducer to modulator
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Mohanraj Rajesh, In PLoS ONE, 2008
... , caspase-3 were purchased from Cell Signaling Technologies, USA Santa Cruz ...
Oct4-induced pluripotency in adult neural stem cells.
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Fimia Gian Maria, In PLoS ONE, 2008
... Anti-phospho-p70S6k, anti-cyclin B, anti-cyclin E and anti-caspase-3 were purchased from Santa Cruz Biotechnology, Inc (Santa Cruz, CA, ...
Effects of diallyl disulfide (DADS) on expression of apoptosis associated proteins in androgen independent human prostate cancer cells (PC-3)
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Daly John M et al., In Journal of Ovarian Research, 2008
... Anti-p27 (sc-528, 1:200), anti-BAX (sc-7480, 1:200), anti-caspase 3 precursor (sc-7148, 1:200), anti-LXRα (sc-1202 1:200), anti LXRβ (sc-130412, 1:200) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin.
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Srivastava Rakesh K., In PLoS ONE, 2008
... We used CM-H2DCFDA from Molecular Probes, Invitrogen, the Caspase 3/CPP32 Colorimetric assay kit from MBL Intl., and Antioxidant capacity ...
Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the β-cell pro-survival effects of glucose-dependent insulinotropic polypeptide
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Liu Li-Bin et al., In International Journal of Endocrinology, 2008
... Rabbit polyclonal antibodies to sheep NH2-terminal kinase (JNK), p-JNK, c-Jun, p-c-Jun, caspase-3 were purchased from Cell Signaling (Beverly, MA, USA) ...
A solution for stripping antibodies from polyvinylidene fluoride immunoblots for multiple reprobing.
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Brandner Johanna M., In PLoS ONE, 2008
... and HRP-conjugated secondary antibodies (Santa Cruz Biotechnology); PKC isotypes (BD Biosciences); FAK, caspase 3 and cleaved caspase 3 (Cell Signaling); polyclonal antibodies against the ...
Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein.
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Aguilar Patricia V., In PLoS ONE, 2008
... Cleaved caspase-3 antibody was purchased from Cell Signaling.
Antileukemic activity of genistein, a major isoflavone present in soy products
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Chi Chin-Wen et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... Mouse monoclonal antibody against caspase-3 was purchased from Imgenex (San Diego, CA, USA) ...
Wnt/β-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells
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Lai Gi-Ming et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... (Santa Cruz, CA), and anticleaved caspase-3 and anti-PARP antibodies were purchased from Cell Signaling Technology, Inc ...
The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis
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Schneider Guenter, In PLoS ONE, 2007
... (20E3), phosphorylated ATR (Ser428) (#2853), phosphorylated Chk1 (Ser296) (#2349), phosphorylated p53 (Ser15) (16G8), Anti-ATR (#2790), anti-caspase 3 (8G10), PARP-1 (#9524S), and α-tubulin (1H10) were purchased from Cell Signaling Technology, while anti-acetylated tubulin ...
Development of reverse genetics systems for bluetongue virus: recovery of infectious virus from synthetic RNA transcripts
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Roy Polly et al., In Virology Journal, 2007
... Antibodies for detection of the caspase-8 (ab25901), caspase-9 (ab25758), caspase-3 (ab17819; ab90437) and anti-HMGB were purchased from Abcam.
Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway
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Gallyas Ferenc, In PLoS ONE, 2007
... Antibody against caspase-3 was purchased from Imgenex (San Diego, CA, USA) ...
The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment
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Mukhopadhyay Partha, In PLoS ONE, 2007
... Voltage-dependent anion channel (VDAC) and caspase-3 Abs were purchased from Cell Signaling Technology, Inc ...
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide
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Wang Chun-Yan et al., In Medical Gas Research, 2007
... Antibodies for detecting bcl-2 and cleaved caspase-3 were obtained from Cell Signaling Technology, Inc (Beverly, MA, ...
The medicinal mushroom Agaricus blazei murrill: review of literature and pharmaco-toxicological problems
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Leu Sew-Fen et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... -actin and the monoclonal antibody against caspase-3, -7, and -9 were purchased from Cell Signaling (Beverly, MA, USA) ...
Seasonal changes in mood and behavior are linked to metabolic syndrome.
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Lu Xin-Yun, In PLoS ONE, 2007
... The caspase-3 antibody was form Cell Signaling (Danvers, MA, USA) ...
Complementary functions of ATM and H2AX in development and suppression of genomic instability
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Malle Ernst et al., In DNA Repair, 2007
... 2550–2600 (Abcam, Cambridge, U.K.) of human ATM; (iii) polyclonal rabbit anti-caspase-3 antibody (raised against full-length caspase-3, Santa Cruz Biotechnology, Santa Cruz, CA, USA), ...
Lung toxicity of 16 fine particles on intratracheal instillation in a bioassay model using f344 male rats
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Srinivasula Srinivasa M., In PLoS ONE, 2007
... LC3B and cleaved caspase-3 primary antibodies were purchased from Cell Signaling Technologies ...
Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.
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Roy Craig R., In PLoS Pathogens, 2006
... from Cell Signaling Technology); goat anti-mouse-HRP and goat anti-rabbit-HRP (both from Jackson ImmunoResearch Laboratories); mouse anti-caspase-3 (BD Biosciences); rabbit anti-RFX5 (Rockland Immunochemicals); ...
von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms
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Patterson Cam et al., In The Journal of Cell Biology, 2006
... Phosphorylated Smad and cleaved Caspase 3 antibodies were purchased from Cell Signaling Technology ...
Apoptosis: a review of programmed cell death.
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Pintus Gianfranco, In PLoS ONE, 2006
... Anti caspase-3(p8) antibody was purchased from Santa Cruz Biotechnology (CA, USA) ...
Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo
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Jung Manfred, In PLoS ONE, 2006
... 3, actin, acetyl-µ-tubulin were from cell signaling were from Cell Signaling Technologies (Boston, MA, USA); caspase 3 was from Imgenex (San diego, CA, USA); ...
Structural basis for recruitment of mitochondrial fission complexes by Fis1
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Mihara Katsuyoshi et al., In The Journal of Cell Biology, 2006
... (BD), and cleaved caspase-3 (Cell Signaling Technology) were purchased from ...
Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-κB pathway
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Li Hao et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2006
... antibody (Cell Signaling Co., Ltd., USA), and caspase-3 rabbit antihuman monoclonal antibody (Beijing Biosynthesis Biotechnology Co., Ltd., Beijing, ...
High NPHP1 and NPHP6 mutation rate in patients with Joubert syndrome and nephronophthisis: potential epistatic effect of NPHP6 and AHI1 mutations in patients with NPHP1 mutations.
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Vij Neeraj, In PLoS ONE, 2006
... ; anti-phospho and total ERK1/2 antibodies and anti-cleaved caspase-3 (asp 175) from Cell signaling (9102, 9101 and 9661); ...
Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo
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Bruni Paola et al., In Biochimie, 2006
... The caspase-3 substrate Ac-DEVD-AFC was from Biomol Research Laboratories Inc ...
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury
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Scott Glynis et al., In The Journal of Investigative Dermatology, 2006
... monoclonal antibodies to phospho-Erk1/Erk2, mouse monoclonal antibodies to total Erk1/Erk2, and rabbit monoclonal antibodies to caspase-3 were purchased from Cell Signaling Technology (Danvers, MA) ...
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
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Zhang Kalin Yan-Bo et al., In Chinese Medicine, 2006
... Primary antibodies against phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) and cleaved caspase-3 (Asp175) were purchased from Cell Signaling (Beverly, MA, USA) ...
A death-promoting role for extracellular signal-regulated kinase
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Wong A S T et al., In British Journal of Cancer, 2005
... Polyclonal antibodies against Akt, phospho-Akt, ERK1/2, phospho-ERK1/2, caspase-9, and caspase-3 were purchased from Cell Signaling (Beverly, MA, USA) ...
Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance
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Reddy Manju B. et al., In Parkinson's Disease, 2005
... Substrate for caspase-3, Acetyl-Asp-Glu-Val-Asp-AFC (Ac-DEVD-AFC), was obtained from MP Biomedicals (Solon, OH) ...
Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat protein.
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Kashanchi Fatah, In PLoS ONE, 2005
... Antibodies for pERK, ERK, pAkt, Akt, pJNK, JNK, Bax, Bcl2 and cleaved caspase-3 were all purchased from Cell Signaling (Danvers, MA, USA) ...
Oncogenic PI3K and its role in cancer
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Nie Daotai, In PLoS ONE, 2005
... anti-MMP-2, anti-Akt, anti-ERK, and anti-TIMP-1 from Santa Cruz Biotechnology (Santa Cruz, CA), anti-p-Akt from and anti-caspase-3 (Cell Signaling) and anti-β-actin, anti-p-MAPK (Sigma ...
A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
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Jin Dong-Yan, In PLoS ONE, 2005
... Mouse monoclonal anti-caspase-3 antibody was purchased from Imgenex (San Diego, CA) ...
Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids
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Kim Dong-Seok et al., In Journal of Biomedical Science, 2005
... against phospho-p38 mitogen-activated protein kinase (MAPK) (Thr180/Tyr182) (CST-9211), phospho-c-Jun-N-terminal kinase (JNK) (Thr183/Tyr185) (CST-9251), and cleaved caspase-3 (CST-9661) were obtained from Cell Signaling Technology (Danvers, MA, USA) ...
Staining protocol for organotypic hippocampal slice cultures
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Lee H-g et al., In Cell Death & Disease, 2005
... -actin antibody was obtained from Millipore (Billerica, MA, USA) and anti-cleaved-caspase-3 antibody was obtained from Cell Signaling Technology (Danvers, MA, USA) ...
Protein phosphatase 1 regulates the stability of the circadian protein PER2
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Yang Y et al., In Cell Death & Disease, 2005
... P-AKT (Ser473), p-AKT (Thr308), p-4E-BP1 (Ser65), p-S6 (S235/236), cleaved-caspase 3 and -9 antibodies were purchased from Cell Signaling Technology (Beverly, MA, USA) ...
A death-promoting role for extracellular signal-regulated kinase
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Yaffe Michael B et al., In Molecular Systems Biology, 2005
... and Cyclin B were obtained from Santa Cruz Biotechnology, against total JNK, total ERK1, and cleaved caspase-3 from BD Biosciences, and against cleaved caspase-3 ...
Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation
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Mayer Bruce J. et al., In Oncogene, 2005
... Antibodies for SAPK/JNK, phospho-SAPK/JNK (Thr183/Tyr185), Akt, phospho-Akt (Ser473), Erk2, phospho-Erk1/2 (Thr202/Tyr204), and cleaved caspase-3 (Asp175) were purchased from Cell Signaling Technology ...
Activation of Bak and Bax through c-Abl-protein kinase C-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
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Hooker Bill, In PLoS ONE, 2005
... Bax, Cyt c, prohibitin and caspase 3 antibodies were obtained from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Identification of prothymosin-α1, the necrosis–apoptosis switch molecule in cortical neuronal cultures
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Ueda Mutsumi et al., In The Journal of Cell Biology, 2005
... , -γ, -ɛ, and -δ (all from Santa Cruz Biotechnology, Inc.); activated caspase-3 and phosphorylated PKCζ (Cell Signaling); and cyto ...
Treatment of hormone-refractory breast cancer: apoptosis and regression of human tumors implanted in mice.
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El-Rifai Wael, In PLoS ONE, 2005
... ), caspase-3, cleaved PARP were obtained from Cell Signaling (Beverly, MA); anti-survivin antibody ...
Green fluorescent protein-expressing Escherichia coli as a selective probe for HOCl generation within neutrophils
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Renshaw Stephen A. et al., In Journal of Leukocyte Biology, 2004
... (A) zVD.fmk 100 μM (pan-caspase inhibitor, Calbiochem, UK); (B) zDEVD.fmk 100 μM (caspase-3 inhibitor, Bachem, Germany); (C) benzyloxycarbonyl-Leu-Glu-His-Asp-fluoro-methylketone (zLEHD.fmk),
Breast cancer
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Eckhart Walter et al., In Breast Cancer Research, 2004
... phospho-Akt (Ser473), phospho-Akt (Ser473 Immunohistochemistry specific), Akt, phospho-mammalian target of rapamycin (mTOR; Ser2448) and cleaved caspase-3 (Asp175) were from Cell Signaling (Beverly, MA, USA); phospho-ERK1/2 ...
Nicotine inactivation of the proapoptotic function of Bax through phosphorylation.
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Bobé Pierre, In PLoS ONE, 2004
... anti-mTOR, polyclonal anti-phospho-mTOR (Ser 2481 and 2448), polyclonal anti-BIM, anti-PP2A/A, anti-PP2A/C, monoclonal anti-caspase-9 and anti-cleaved caspase-3 were purchased from Cell Signaling (Beverly, MA) ...
Lipooligosaccharide-independent alteration of cellular homeostasis in Neisseria meningitidis-infected epithelial cells.
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Seifert H. Steven, In PLoS Pathogens, 2004
... Caspase 3 Assay Kit, Polymixin B and Staurosporine (STRP) were purchased from Sigma Aldrich (Lyon, France) ...
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
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Lin Sheng-Zhang et al., In International Journal of Biological Sciences, 2004
... against Bax and Bcl-2, phospho-mTOR(Ser2448), Rictor-mTOR, phospho-Akt(Ser473), rabbit monoclonal antibody against NF-κB(p65), survivin and active caspase 3 were purchased from Abcam (Cambridge, UK) ...
Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression
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Myung Ki-Bum et al., In Journal of Korean Medical Science, 2004
... Rabbit monoclonal anti-cleaved caspase-3 (Asp175) antibody was purchased from Cell Signaling Technology, Inc (Danvers, MA, ...
Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space
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Ding Min et al., In Journal of Nanobiotechnology, 2004
... Total Akt (Akt), phospho-Akt (p-Akt, ser 473), BID, and cleaved caspase-3 antibodies were purchased from Cell Signaling Technology (Beverley, MA) ...
Human tumor cell growth inhibition by nontoxic anthocyanidins, the pigments in fruits and vegetables
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Wulf Gerburg M et al., In Breast Cancer Research : BCR, 2004
... Cambridge, MA, USA), anti-ALDH1A1 antibody (ab52492, rabbit monoclonal antibody, EP1933Y; Abcam, Cambridge, MA, USA), anti-cleaved caspase 3 antibody (9661S, rabbit polyclonal antibody, Asp175; Cell Signaling Technology, Danvers, MA, USA), ...
Caveolin-1 is not essential for biosynthetic apical membrane transport.
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Du Quansheng, In PLoS ONE, 2004
... Rabbit anti-cleaved caspase-3 was from Cell signaling technology ...
Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora
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Yokozawa Takako et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2003
... anti-reduced nicotinamide adenine dinucleotide phosphate oxidase-4 (Nox-4) (LifeSpan BioSciences, Seattle, WA, USA) and mouse monoclonal caspase-3 (BioVision Inc., Mountain View, CA, ...
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53.
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Chandra Dhyan, In PLoS ONE, 2003
... Antibodies against phospho-p38 MAPK (Thr180/Tyr182), phospho-JNK1/2 (Thr183/Tyr185), phospho-ERK1/2 (Thr202/Tyr204), phospho-eIF2α (Ser51), eIF2α and active caspase-3 were obtained from Cell Signaling Technology (Beverly, MA) ...
Prodrug modification increases potassium tricyclo[5.2.1.0(2,6)]-decan-8-yl dithiocarbonate (D609) chemical stability and cytotoxicity against U937 leukemia cells
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Ségui Bruno et al., In International Journal of Molecular Sciences, 2003
... Sigma (Saint Quentin Fallavier, France); zVAD(OMe)-fmk (40 μM) was purchased from Bachem (Voisins-Le-Bretonneux, France); polyclonal anti-caspase-3 (10 μg/mL) was obtained from Dako (Trappes, France); monoclonal anti-PARP ...
Proteins released from degenerating neurons are surrogate markers for acute brain damage.
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Di Giovanni Simone, In PLoS ONE, 2003
... Biotechnology), mouse anti-CDK1 (Santa Cruz Biotechnology), mouse anti-E2F1 (BD pharmingenTM), rabbit anti-phospho(Ser)-CDK substrate, rabbit anti-cleaved caspase 3 (Cell Signaling Technology), anti-pS54-n-myc (Bethyl Laboratories ...
Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage
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Caccamo Daniela et al., In BMC Neuroscience, 2003
... Mouse monoclonal antibodies against Bcl-2 and caspase-3 were from BioVision (Mountain View, USA) ...
Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway.
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Unutmaz Derya, In PLoS ONE, 2002
... Bioscience, San Diego, CA) and TRAIL R2 for Western blot (Capralogics Inc., Hardwick, MA), active caspase-3 (BD Biosciences).
Immunotoxin resistance in multidrug resistant cells
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Howell Stephen B. et al., In Cancer Chemotherapy and Pharmacology, 2002
... Rabbit polyclonal antibody against active + pro Caspase 3 was purchased from Abcam, Inc ...
Drosophila p53 preserves genomic stability by regulating cell death.
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Hawley R. Scott, In PLoS Genetics, 2002
... eye discs was visualized using the cleaved caspase-3 antibody (protocol adapted from [63]) from Cell Signaling Technologies (cat ...
Receptor-mediated choreography of life and death
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Chen Baoan et al., In International Journal of Nanomedicine, 2002
... assay kit (Biosynthesis Biotechnology Co., Ltd., Beijing, China); anti-bcl-2, anti-bax, anti-survivin (Bioworld), anti-bcl-rambo (Biovision), anti-active caspase-3 (Cell Signaling), anti-GAPDH (Santa Cruz, CA), ...
Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling
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Janssen-Heininger Yvonne M.W. et al., In The Journal of Cell Biology, 2002
... The following antibodies were used: Fas (Millipore), FADD (MBL International), caspase-8 (Enzo Biochem, Inc.), caspase-3 (Cell Signaling Technology), glutathione (Virogen), biotin ...
Retroactive pathway involving mitochondria in electroloaded cytochrome c-induced apoptosis. Protective properties of Bcl-2 and Bcl-XL.
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Rieux-Laucat Frederic, In PLoS ONE, 2002
... Biosciences (Le Pont-de-Claix, France); monoclonal anti-caspase-10 (clone 4C1; 1 µg/mL) was from MBL (Meudon, France); polyclonal anti-caspase-3 (10 µg/mL) was from Dako (Trappes, France); monoclonal anti-caspase-2 ...
Mucalpain activation in β-Lapachone-mediated apoptosis
Supplier
Brown Jayann et al., In Cancer Cell International, 2002
... The caspase 3 inhibitor, DEVD-fmk and substrate DEVD-afc were purchased from Biovision (Palo Alto, CA) ...
C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus
Supplier
Clurman Bruce, In PLoS Genetics, 2001
... Antibodies anti-p-JNK, anti-p-MKK-4, anti-p-Src(416), and cleaved caspase-3 were from Cell Signaling; anti-SRC, anti-JNK (C-17), anti-MKK4, ...
Asynchronous exponential growth in an age structured population of proliferating and quiescent cells
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Webb Glenn F et al., In Theoretical Biology & Medical Modelling, 2001
... Primary antibodies include Ki-67 (Calbiochem) and cleaved caspase-3 (Cell Signaling, Danvers, MA) ...
A model of tobacco smoke-induced airflow obstruction in the guinea pig
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Chatterjee Indu B et al., In Journal of Inflammation (London, England), 2001
... Antibodies against p53, phosphorylated p53, Bax, Bcl-2, caspase 3 and anti-mouse-HRP, anti-rabbit HRP antibodies as well as the chemiluminescent kit for immunoblot analysis were obtained from Cell signaling Technology, Inc ...
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
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Nie Jing et al., In International Journal of Biological Sciences, 2000
... (FBS) and trypsin/EDTA solution were purchased from Invitrogen (Carlsbad, CA); Antibodies against Numb and cleaved caspase-3 were purchased from Cell Signaling (Danvers, MA); Antibodies against ...
Alteration of Epithelial Structure and Function Associated with PtdIns(4,5)P2 Degradation by a Bacterial Phosphatase
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Grinstein Sergio et al., In The Journal of General Physiology, 2000
... Monoclonal antibodies against active caspase 3 were from BD Biosciences.
Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway.
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Blagosklonny Mikhail V., In PLoS ONE, 2000
... Additional polyclonal antibodies directed against caspase 3 (9661), cleaved caspase 3 (9662), and PARP (9532) were purchased from Cell Signaling Technology (Beverly, MA) ...
Nuclear factor-kappaB-mediated X-linked inhibitor of apoptosis protein expression prevents rat granulosa cells from tumor necrosis factor alpha-induced apoptosis
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Asselin Eric et al., In Reproductive biology and endocrinology : RB&E, 2000
... PhosphoPlus Akt (Ser473), PhosphoPlus Akt (Ser473) IHC specific, Akt, PTEN, procaspase-3 and cleaved specific caspase-3 antibodies were obtained from New England Biolabs (Mississauga, ON) ...
Discriminating mild parkinsonism: methods for epidemiological research
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Hsu Hung-Te et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2000
... , rabbit antibody against TH and caspase-3, and all horseradish peroxidase-conjugated secondary antibodies were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.
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Ahmad Aamir, In PLoS ONE, 2000
... phosphor-NF-κB p65 (Ser536), cleaved caspase-3, caspase-9 and 8 were purchased from Cell Signaling Technology® (Boston, MA); caspase-3 was purchased from Imgenex (San Diego, CA); cytochrome ...
The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c
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Martin Seamus J. et al., In The Journal of Experimental Medicine, 1999
... ); antibodies selectively recognizing active caspase-3 were purchased from New England Biolabs, Inc.; and anti-actin and ...
Alterations in large and small proteoglycans in bleomycin-induced pulmonary fibrosis in rats
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Brömme Dieter et al., In Respiratory Research, 1999
... Antibodies against Bax, Bcl-2 and cleaved caspase-3 were obtained from Cell Signaling Technology (Danvers, MA, USA) ...
β-Carbolines that accumulate in human tissues may serve a protective role against oxidative stress
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Kim Doo-Eung et al., In Journal of Clinical Neurology (Seoul, Korea), 1999
... Quantikine® M rat/mouse cytochrome c assay kit was obtained from R&D systems (Minneapolis, MN, USA), and ApoAlert™ CPP32/caspase-3 assay kit was from CLONTECH Laboratories Inc ...
Molecular mechanism of violacein-mediated human leukemia cell death
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Santos Elizeu et al., In Marine Drugs, 1999
... Rabbit polyclonal antibodies to human Bax and Bcl-2, rabbit anti-cleaved caspase-3 monoclonal antibody and secondary antibody produced in conjunction with peroxidase goat anti-rabbit were obtained from Cell Signaling Technology (Beverly, MA, USA) ...
Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer
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Laidler Piotr et al., In Journal of Cancer Research and Clinical Oncology, 1999
... Fluorogenic substrate for caspase-3 (Ac-DEVD-AFC) was purchased from MP Biomedicals (Solon, OH, USA), TiterTACS ...
Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage
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Shiloh Yosef et al., In The Journal of Cell Biology, 1999
... Chemicon; α-nucleostemin was obtained from R&D Systems; α-phospho-Cdk1 (pTyr15), α-phospho-Cdk1 (pThr161), α-phospho- p53 (Ser46), α-cleaved caspase 3 (5A1), and α–PARP-1 were obtained from Cell Signaling Technology, Inc.; anti-H2B, α-p53 ...
Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K+-ATPase through proteasomal and endo−/lysosomal proteolytic pathways.
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Maki Carl G., In PLoS ONE, 1998
... (Littleton, CO); anti-glyceraldehyde 3-phosphate dehydrogenase (GAPDH), p-JNK, JNK, poly (ADP-ribose) polymerase (PARP), caspase 12, and caspase 3 antibodies were purchased from Cell Signaling Technology (Beverly, MA); the ...
Effect of recombinant human erythropoietin on endothelial cell apoptosis
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Kim Woo Taek et al., In Korean Journal of Pediatrics, 1998
... Cruz Biotechnology, Santa Cruz, CA, USA), Bax (1:1,000; Cell Signaling technolog, Danvers, MA, USA) and caspase-3 (1:1,000; Cell Signaling technology) ...
Interaction of tissue transglutaminase with nuclear transport protein importin-α3
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Kojima Soichi et al., In Molecular Cancer, 1998
... and anti-cleaved caspase 3 antibodies were from Cell Signaling Technology (Danvers, MA) ...
Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons.
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LeBlanc Andrea C., In PLoS ONE, 1998
... 9762), antibody against caspase-3 was from Cell Signaling Technology (cat ...
Mitochondrial depolarization is not required for neuronal apoptosis
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Giese Alf et al., In Neuro-Oncology, 1998
... against p21, mdm2, TBP (Santa Cruz Biotechnology), pig3 (Calbiochem), α-tubulin (Oncogene), bax (Upstate), or cleaved caspase-3 (Cell Signaling Technology, Inc.) ...
Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates.
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Hoyt Kari, In PLoS ONE, 1998
... The anti-cleaved caspase 3 antibody was purchase from Cell Signaling (9664; Danvers, MA, USA) ...
Tumor-specific killer cells in paraneoplastic cerebellar degeneration
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Rosen Antony et al., In The Journal of Experimental Medicine, 1997
... Purified caspase-3 and -8 and CrmA (cytokine response modifier 1) were gifts from Nancy Thornberry (Merck Research Labs., Rahway, NJ) ...
Regulation of cytochrome c oxidase activity by c-Src in osteoclasts
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Baron Roland et al., In The Journal of Cell Biology, 1997
... Anti-cleaved caspase-3 antibody was purchased from New England Biolabs, Inc ...
Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis
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Lowe Martin et al., In The Journal of Cell Biology, 1997
... Vas Ponnambalam, Leeds University, Leeds, UK), monoclonal anti-PARP from Calbiochem and polyclonal anti–caspase 2 (C-20) and –caspase 3 (N-19) from Santa Cruz Biotechnology, Inc., polyclonal anti–golgin-160 (a ...
Review of mechanisms underlying anticarcinogenicity by Brassica vegetables
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Fares F A et al., In British Journal of Cancer, 1996
... Anti-caspase 3 and anti-cytochrome c monoclonal antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Bcl-2 prevents nitric oxide-mediated apoptosis and poly(ADP-ribose) polymerase cleavage
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Porter Alan G. et al., In Nucleic Acids Research, 1996
... The antibodies against caspase-3 were from Cell Signaling Technology or Santa Cruz ...
Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner
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Bréard Jacqueline et al., In The Journal of Experimental Medicine, 1995
... Cruz Biotechnology, Inc.) and anti–Rock II COOH terminus (C-19; Santa Cruz Biotechnology, Inc.); anticleaved (Asp175) caspase-3 (Cell Signaling); anti-AU1 (Babco); anti-MLC (MY21; ...
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell–derived neural transplants
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Condie Brian G. et al., In The Journal of Cell Biology, 1995
... Polyclonal anti-cleaved caspase 3 rabbit IgG was purchased from Cell Signaling Technologies ...
Human ICE/CED-3 protease nomenclature
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Zheng Liu et al., In Journal of Experimental & Clinical Cancer Research : CR, 1995
... Caspase colorimetric assay kit and anti-caspase-3 antibody were from Biovision.
Metabolism and actions of 2-chloro-9-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)-adenine in human lymphoblastoid cells.
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Singh Amit, In PLoS ONE, 1994
... Primary antibodies (Ab) used in this study were: rabbit (Rb) pAb to caspase-3 (Biomol, Cat # SA320); mAbs to ...
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
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Tang Dean G., In PLoS ONE, 1994
... Rabbit anti-human caspase-3 (active) antibodyEpitomics, Inc. ...
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
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Pyne Nigel J. et al., In Cellular Signalling, 1993
... ), anti-PARP and anti-cleaved caspase-3 antibodies were from Cell Signalling Technology (New England Biolabs (UK) Ltd., Hitchin, UK) ...
Neuronal ubiquitin and neurofilament expression in different lysosomal storage disorders
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Elleder Milan et al., In Acta Neuropathologica, 1991
... Activated caspase 3 (rabbit monoclonal)Epitomics, Burlingame, CA, USA ...
The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions.
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Lipshitz H. D., In G3: Genes|Genomes|Genetics, 1990
... analysis, the following primary antibodies were used: rat anti-BrdU (1:100; Abcam, Cambridge, MA), rabbit anti-cleaved Caspase 3 (1:500; Cell Signaling Technology, Beverly, MA), rat ...
Changes in the cell kinetics of pig epidermis after single doses of X rays.
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Borgmann Kerstin, In PLoS ONE, 1987
... Rabbit polyclonal anti-active Caspase 3,Ab138471/200Abcam ...
Effects of new bisphosphonic acids on tumor-induced bone destruction in the rat
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Geilen C C et al., In British Journal of Cancer, 1985
... Anti-caspase-3 antibodies (rabbit) were obtained from Pharmingen (Hamburg, Germany) and horseradish peroxidase-conjugated secondary antibodies were purchased from Dako (Hamburg, Germany) ...
Consumption of dairy produce and alcohol in a case-control study of breast cancer
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Bieberich Erhard et al., In Breast Cancer Research : BCR, 1985
... Cleaved (active) caspase-3 antibody was from Cell Signaling Technology (Beverly, MA, USA) ...
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
Supplier
Figueiredo-Pereira M E et al., In Cell Death & Disease, 1982
... L Binder (Northwestern University, Chicago, IL, USA); rabbit polyclonal anti-caspase 3 (1:1000, cat# 9662, Cell Signaling Technology, Danvers, MA, USA) ...
Rapid colorimetric assay for cellular growth and survivals: application to proliferation and cytotoxicity assays
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de las Heras B et al., In Cell Death & Disease, 1982
... the following suppliers: anti-ERK, anti-pERK, anti-JNK, anti-pJNK, anti-p38, anti-pp38, anti-AKT, anti-pAKT(S-473), anti-pAKT (T-308), anti-AMPK, anti-pAMPK, anti-caspase-3 (Cell Signaling Technologies, Beverly, MA, USA); ...
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