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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

PDLIM1 interacting kinase 1 like

casein kinase
Top mentioned proteins: CAN, CKI, V1a, ACID, HAD
Papers on casein kinase
Soy Isoflavone Genistein-Mediated Downregulation of miR-155 Contributes to the Anticancer Effects of Genistein.
New
Dharmawardhane et al., San Juan, Puerto Rico. In Nutr Cancer, Feb 2016
In parallel with reduced cell viability, miR-155 is downregulated, whereas proapoptotic and anticell proliferative miR-155 targets FOXO3, PTEN, casein kinase, and p27 are upregulated in MDA-MB-435 and Hs578t cells in response to genistein treatment.
Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43.
New
Hasegawa et al., Tokyo, Japan. In J Biol Chem, Feb 2016
We found that expression of hyperactive form of casein kinase 1 delta (CK1δ1-317: a C-terminally truncated form) promotes mislocalization and cytoplasmic accumulation of phosphorylated TDP-43 (ubiquitin- and p62-positive) in cultured neuroblastoma SH-SY5Y cells.
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from corydalis cava (fumariaceae) as Alzheimer's disease targets.
New
Andrisano et al., Hradec Králové, Czech Republic. In Fitoterapia, Feb 2016
Not all compounds showed activity against glycogen synthase kinase-3β (GSK-3β) and casein kinase-1δ (CK-1δ).
Casein Kinase 2-A Kinase that Inhibits Brown Fat Formation.
New
Impact
Enerbäck, Göteborg, Sweden. In Cell Metab, Jan 2016
(2015) use phosphoproteomics to identify casein kinase 2 (CK2) as a suppressor of brown adipocyte formation, providing insights into how adipose tissue regulates its composition of white versus brown adipocytes.
Dynamic conformational ensembles regulate casein kinase-1 isoforms: Insights from molecular dynamics and molecular docking studies.
New
Gupta et al., Allahābād, India. In Comput Biol Chem, Jan 2016
UNASSIGNED: Casein kinase-1 (CK1) isoforms actively participate in the down-regulation of canonical Wnt signaling pathway; however recent studies have shown their active roles in oncogenesis of various tissues through this pathway.
Optimizing a Male Reproductive Aging Mouse Model by d-Galactose Injection.
New
Lin et al., Taipei, Taiwan. In Int J Mol Sci, Dec 2015
Several of these genes are critical for forming sperm-head morphologies or maintaining nuclear integration (e.g., cylicin, basic protein of sperm head cytoskeleton 2 (Cylc2), casein kinase 2, alpha prime interacting protein (Csnka2ip) and katanin p80 (WD40-containing) subunit B1 (Katnb1)).
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.
New
Impact
Ebert et al., Boston, United States. In Nature, Aug 2015
Here, we demonstrate that lenalidomide induces the ubiquitination of casein kinase 1A1 (CK1α) by the E3 ubiquitin ligase CUL4-RBX1-DDB1-CRBN (known as CRL4(CRBN)), resulting in CK1α degradation.
NUCKS: a potential biomarker in cancer and metabolic disease.
Review
New
Tergaonkar et al., Singapore, Singapore. In Clin Sci (lond), Jun 2015
Nuclear, casein kinase and cyclin-dependent kinase substrate (NUCKS), a protein similar to the HMG (high-mobility group) protein family, is one of the most modified proteins in the mammalian proteome.
Drugs under early investigation for the treatment of bipolar disorder.
Review
New
Michalopoulou et al., Athens, Greece. In Expert Opin Investig Drugs, Apr 2015
Glycogen synthase kinase 3, casein kinase 1, inositol monophosphatase inhibition, histone deacetylase inhibition pathways are known targets that should proceed from preclinical to the clinical trial level.
Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation.
Impact
Rosenfeld et al., San Diego, United States. In Nature, 2015
This regulation is based on the phosphorylation of a highly conserved tyrosine residue, Tyr 57, in histone H2A and is mediated by the unsuspected tyrosine kinase activity of casein kinase 2 (CK2).
TTBK2: a tau protein kinase beyond tau phosphorylation.
Review
Chang et al., Taipei, Taiwan. In Biomed Res Int, 2014
TTBK2 possesses a casein kinase 1 (CK1) kinase domain followed by a ~900 amino acid segment, potentially responsible for its localization and substrate recruitment.
Unconventional Functions of Mitotic Kinases in Kidney Tumorigenesis.
Review
Arlot-Bonnemains et al., Rennes, France. In Front Oncol, 2014
Aneuploidy can also result from the loss of cell-cell adhesion and apical-basal cell polarity that also may be regulated by the mitotic kinases (polo-like kinase 1, casein kinase 2, doublecortin-like kinase 1, and Aurora kinases).
Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.
Impact
Ebert et al., Boston, United States. In Cancer Cell, 2014
The casein kinase 1A1 gene (CSNK1A1) is a putative tumor suppressor gene located in the common deleted region for del(5q) myelodysplastic syndrome (MDS).
Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.
Review
Sinnberg et al., Tübingen, Germany. In Mol Cancer, 2013
Isoforms of the casein kinase 1 (CK1) family have been shown to phosphorylate key regulatory molecules involved in cell cycle, transcription and translation, the structure of the cytoskeleton, cell-cell adhesion and receptor-coupled signal transduction.
RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.
Impact
Niehrs et al., Heidelberg, Germany. In Science, 2013
Casein kinase 1 (CK1) members play key roles in numerous biological processes.
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