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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ankyrin repeat domain 1

CARP, CA8, ANKRD1, Cardiac ankyrin repeat protein
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, ACID, CAN, titin, Ankrd2
Papers on CARP
Srv2/CAP is required for polarized actin cable assembly and patch internalization during clathrin-mediated endocytosis.
Toshima et al., Tokyo, Japan. In J Cell Sci, Feb 2016
We find that the C-terminal CARP domain of Srv2p is vitally important for the proper assembly of actin patches and cables; we also demonstrate that the N-terminal helical folded domain of Srv2 is required for its localization to actin patches, specifically to the ADP-actin rich region through an interaction with cofilin.
ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells.
Nakahata et al., Sendai, Japan. In Cell Signal, Jan 2016
Furthermore, microarray analysis performed in PC12 cells using ERK5 and ERK1/2-specific inhibitors, identified ankyrin repeat domain 1 (ankrd1) as an ERK5-dependent and ERK1/2-independent gene.
Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells.
Hsieh et al., Nehe, China. In Tumour Biol, Jan 2016
UNASSIGNED: Carbonic anhydrase 8 (CA8), a member of the carbonic anhydrase family, is one of the three isozymes that do not catalyze the reversible hydration of carbon dioxide due to the lack of one important histidine.
Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer.
Watanabe et al., Japan. In Oncotarget, Jan 2016
RAB25 expression inhibited IFI16 and PTRF, while ESRP1 expression suppressed ANKRD1, ETS1, and KIAA1199.
Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKCγ Activity and Regulates Purkinje Cell Dendritic Growth.
Kapfhammer et al., Basel, Switzerland. In Mol Neurobiol, Oct 2015
Out of these candidates, we have further studied carbonic anhydrase 8 (CA8).
Microbial source markers assessment in the Bogotá River basin (Colombia).
Campos et al., Barcelona, Spain. In J Water Health, Sep 2015
For this, we determined non-discriminating indicators such as Escherichia coli, somatic coliphages and phages infecting strain RYC2056 of Bacteroides, and potential source tracking markers as phages infecting strains GA17, HB13, and CA8 of Bacteroides, sorbitol-fermenting bifidobacteria, and molecular markers of Bifidobacterium adolescentis, Bifiodobacterium dentium, and Bacteroidetes in raw municipal wastewaters, slaughterhouse wastewaters, and the Bogotá River.
Identification and Testing of Novel CARP-1 Functional Mimetic Compounds as Inhibitors of Non-Small Cell Lung and Triple Negative Breast Cancers.
Rishi et al., In J Biomed Nanotechnol, Sep 2015
Here we report that CARP-1 functional mimetic (CFMs) compounds 4 and 5, and 4.6, a structurally related analog of CFM-4, are potent inhibitors of TNBC and NSCLC cells in vitro.
PTHrP attenuates osteoblast cell death and apoptosis induced by a novel class of anti-cancer agents.
Datta et al., Detroit, United States. In Endocrine, Sep 2015
Apoptosis regulatory protein (CARP)-1 functional mimetics (CFMs) belong to a novel class of compounds that possess anti-cancer properties with potential utility in breast and other cancers.
[Analysis on the change of genotype of enteroviruses associated hand, foot and mouth disease in Beijing during 2013 to 2014].
Zhu et al., In Zhonghua Er Ke Za Zhi, Aug 2015
Twenty six of the 89 other EVs included CA2, CA5, CA8, CA9, CA12, CA14, CB2, CB5, E6, E9 and E25, each genotype of which was no more than 3.
[Effects of tobacco garlic crop rotation and intercropping on tobacco yield and rhizosphere soil phosphorus fractions].
Yang et al., In Ying Yong Sheng Tai Xue Bao, Jul 2015
For the inorganic phosphorus in rhizosphere and non-rhizosphere soil in different treatments, the contents of O-P and Fe-P were the highest, followed by Ca2-P and Al-P, and Ca8-P and Ca10-P were the lowest.
Phosphate removal from domestic wastewater using thermally modified steel slag.
Wang et al., Beijing, China. In J Environ Sci (china), Jun 2015
Ca8-P 17.8%-25.0%,
CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis.
Rishi et al., Detroit, United States. In Oncotarget, Apr 2015
CARP-1/CCAR1 (Cell division cycle and apoptosis regulator 1), a peri-nuclear phospho-protein, plays a dynamic role in regulating cell growth and apoptosis by serving as a co-activator of steroid/thyroid nuclear receptors, β-catenin, Anaphase Promoting Complex/Cyclosome (APC/C) E3 ligase, and tumor suppressor p53.
Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.
Watanabe et al., Tokyo, Japan. In Curr Top Microbiol Immunol, 2014
For example, the CARP-1 protein found in Meretrix lamarckii consists of an enzymatic domain without a possible receptor-binding domain.
'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII.
Wildemann et al., Heidelberg, Germany. In J Neuroinflammation, 2014
Part 1 focuses on anti-metabotropic glutamate receptor 1-, anti-Homer protein homolog 3-, anti-Sj/inositol 1,4,5-trisphosphate receptor- and anti-carbonic anhydrase-related protein VIII-associated autoimmune cerebellar ataxia (ACA); part 2 covers anti-protein kinase C gamma-, anti-glutamate receptor delta-2-, anti-Ca/RhoGTPase-activating protein 26- and anti-voltage-gated calcium channel-associated ACA; and part 3 reviews the current knowledge on anti-Tr/delta notch-like epidermal growth factor-related receptor-, anti-Nb/AP3B2-, anti-Yo/cerebellar degeneration-related protein 2- and Purkinje cell antibody 2-associated ACA, discusses differential diagnostic aspects and provides a summary and outlook.
Carbonic anhydrase related proteins: molecular biology and evolution.
Parkkila et al., Tampere, Finland. In Subcell Biochem, 2013
The three CARPs in vertebrates are known as CARP VIII, X and XI.
Loss of desmin triggers mechanosensitivity and up-regulation of Ankrd1 expression through Akt-NF-κB signaling pathway in smooth muscle cells.
Boriek et al., Houston, United States. In Faseb J, 2012
Ankrd1 and desmin may play important roles in airway smooth muscle cell homeostasis.
Phenotypical spectrum of cerebellar ataxia associated with a novel mutation in the CA8 gene, encoding carbonic anhydrase (CA) VIII.
Al-Owain et al., Riyadh, Saudi Arabia. In Am J Med Genet B Neuropsychiatr Genet, 2011
This report expands the neurological and radiological phenotype associated with CA8 mutations.
Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathy.
Lim et al., Boston, United States. In Plos One, 2011
These data demonstrate co-dependent roles for GATA4 and CARP in regulating sarcomere gene expression and maintaining sarcomeric organization in cardiomyocytes in culture.
Carbonic anhydrase-related protein VIII is expressed in rod bipolar cells and alters signaling at the rod bipolar to AII-amacrine cell synapse in the mammalian retina.
Taylor et al., Portland, United States. In Eur J Neurosci, 2011
The datum of this study provide evidence that the CAVIII protein, which is highly conserved in vertebrates, is selectively expressed within neural circuits, and may be important for modulating retinal neurotransmission.
Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease.
Faulkner et al., Belgrade, Serbia. In Crit Rev Clin Lab Sci, 2011
Although analyzed in a limited number of patients, there is a considerable body of evidence that MARP proteins could be suitable candidates for prognostic and diagnostic biomarkers.
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