[Up-to-date findings in the host defence mechanism to cryptococcus infection].
In Nihon Ishinkin Gakkai Zasshi, 2013
Recently, we found that caspase recruitment domain family member (CARD9), an adaptor protein in a signal transduction triggered by C-type lectin receptors, plays a key role in the early production of IFN-γ at the site of infection by recruiting NK cells and CD4(+) and CD8(+) memory-phenotype T cells.
Primary immunodeficiencies underlying fungal infections.
New York City, United States. In Curr Opin Pediatr, 2013
Inborn errors of interleukin-17 immunity have recently been shown to underlie chronic mucocutaneous candidiasis (CMC), while inborn errors of caspase recruitment domain-containing protein 9 (CARD9) immunity underlie deep dermatophytosis and invasive candidiasis.
Deep dermatophytosis and inherited CARD9 deficiency.
Aş Şanamayn, Syria. In N Engl J Med, 2013
Because CARD9 (caspase recruitment domain-containing protein 9) deficiency has been reported in an Iranian family with invasive fungal infections, we also sequenced CARD9 in the patients.