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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Carbohydrate

carbohydrate sulfotransferase, GST-1, CHST1, KSST
This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: GST, POLYMERASE, HAD, fibrillin-1, ACID
Papers on carbohydrate sulfotransferase
Identification of polymorphic variants associated with erlotinib-related skin toxicity in advanced non-small cell lung cancer patients by DMET microarray analysis.
New
Tagliaferri et al., Catanzaro, Italy. In Cancer Chemother Pharmacol, Jan 2016
RESULTS: Seven SNPs in six genes (CYP27B1, MAT1A1, CHST1, CYP4B1, ADH6, and SLC22A1) were associated with the occurrence of SR or with a protective effect.
A Carbohydrate Sulfotransferase-6 (CHST6) gene mutation is associated with Macular Corneal Dystrophy in Labrador Retrievers.
New
Mellersh et al., United Kingdom. In Vet Ophthalmol, Dec 2015
PURPOSE: To locate and identify variants associated with macular corneal dystrophy (MCD) in Labrador Retriever (LR) dogs, in the candidate gene carbohydrate sulfotransferase-6 (CHST6).
Small interfering RNA therapy against carbohydrate sulfotransferase 15 inhibits cardiac remodeling in rats with dilated cardiomyopathy.
New
Suzuki et al., Niigata, Japan. In Cell Signal, Jul 2015
Carbohydrate sulfotransferase 15 (CHST15) is a sulfotransferase responsible for biosynthesis of chondroitin sulfate E (CS-E), which plays important roles in numerous biological events such as biosynthesis of proinflammatory cytokines.
Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model.
Koido et al., Tokyo, Japan. In Plos One, 2014
In this study, to clarify the direct role of CS-E in tumor, but not stromal, cells of PDAC, we focused on carbohydrate sulfotransferase 15 (CHST15), a specific enzyme that biosynthesizes CS-E, and investigated the effects of the CHST15 siRNA on tumor cell proliferation in vitro and growth in vivo.
Molecular analysis of the CHST6 gene in Korean patients with macular corneal dystrophy: Identification of three novel mutations.
Kim et al., Seoul, South Korea. In Mol Vis, 2014
Polymerase chain reaction was performed for coding regions of the carbohydrate sulfotransferase (CHST6), gene followed by bidirectional sequencing.
RNA interference targeting carbohydrate sulfotransferase 3 diminishes macrophage accumulation, inhibits MMP-9 expression and promotes lung recovery in murine pulmonary emphysema.
Kimura et al., Kashihara, Japan. In Respir Res, 2014
In a murine model of elastase-induced pulmonary emphysema, we found increased carbohydrate sulfotransferase 3 (CHST3), a specific enzyme that synthesizes chondroitin 6-sulfate proteoglycan (C6SPG).
Characterisation of Dermanyssus gallinae glutathione S-transferases and their potential as acaricide detoxification proteins.
Nisbet et al., Penicuik, United Kingdom. In Parasit Vectors, 2014
The transcripts represented by 3 contigs, designated Deg-GST-1, -2 and -3, were fully sequenced and further characterized by phylogenetic analysis.
Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine.
Bottazzi et al., Houston, United States. In Hum Vaccin Immunother, 2014
A bivalent human hookworm vaccine composed of the Necator americanus Glutathione S-Transferase-1 (Na-GST-1) and the Necator americanus Aspartic Protease-1 (Na-APR-1 (M74)) is currently under development by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP).
The role of hypercholesterolemic diet and vitamin E on Nrf2 pathway, endoplasmic reticulum stress and proteasome activity.
Kartal-Ozer et al., Turkey. In Free Radic Biol Med, 2014
In order to elucidate in vivo role of oxidative stress and ER stress in cardiovascular system of hypercholesterolemic rabbits, we investigated serum levels of cholesterol, MDA and vitamin E and Nrf2, GST-1, GRP78, GRP94, PERK, IRE1 protein levels and the proteasomal activity in aortic tissues will be discussed.
Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.
Ceccarelli et al., Houston, United States. In Acta Crystallogr Sect F Struct Biol Commun, 2014
Glutathione S-transferase 1 from Necator americanus (Na-GST-1) is a vaccine candidate for hookworm infection that has a high affinity for heme and metal porphyrins.
Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate.
Elena Bottazzi et al., Houston, United States. In Hum Vaccin Immunother, 2013
Previously, we reported on the expression and purification of a highly promising hookworm vaccine candidate, Na-GST-1, an N. americanus glutathione s-transferase expressed in Pichia pastoris (yeast), which led to production of 1.5 g of 95% pure recombinant protein at a 20L scale.
The Human Hookworm Vaccine.
Review
Russell et al., Houston, United States. In Vaccine, 2013
The candidate vaccine is comprised of two recombinant antigens known as Na-GST-1 and Na-APR-1, each of which is an important parasite enzyme required for hookworms to successfully utilize host blood as a source of energy.
Expression of long-form N-acetylglucosamine-6-O-sulfotransferase 1 in human high endothelial venules.
GeneRIF
Nakayama et al., Matsumoto, Japan. In J Histochem Cytochem, 2012
found endogenous expression of the long form of the enzyme in human tissue, predominantly in the trans-Golgi network of endothelial cells that form human high endothelial venules.
Novel O-linked glycans containing 6'-sulfo-Gal/GalNAc of MUC1 secreted from human breast cancer YMB-S cells: possible carbohydrate epitopes of KL-6(MUC1) monoclonal antibody.
GeneRIF
Yamashita et al., Yokohama, Japan. In Glycobiology, 2012
Epitope expressing changes with suppression or over-expression of the Gal6ST (Gal 6-O-sulfotransferase) gene, suggesting that Gal6ST is involved in the biosynthesis of the unique epitopes of KL-6/mAb.
Potency testing for the experimental Na-GST-1 hookworm vaccine.
Review
Bethony et al., Washington, D.C., United States. In Expert Rev Vaccines, 2010
Herein, we discuss the evolution of our thinking regarding the design of a potency assay along these newly defined lines and its application to the release of the experimental Necator americanus-glutathione-S- transferase-1 (Na-GST-1) vaccine to prevent human hookworm infection.
The roles of chondroitin-4-sulfotransferase-1 in development and disease.
Review
Kl├╝ppel, Chicago, United States. In Prog Mol Biol Transl Sci, 2009
Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units.
Spondyloepiphyseal dysplasia, Omani type: further definition of the phenotype.
GeneRIF
Robertson et al., Amsterdam, Netherlands. In Am J Med Genet A, 2008
A new point mutation in C6ST-1 is associated with spondyloepiphyseal dysplasia, Omani type.
Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans.
GeneRIF
Akama et al., Los Angeles, United States. In J Biol Chem, 2007
sulfated keratan sulfate is produced by beta3GNT7, beta4GalT4, CGn6ST, and KSG6ST
Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth.
GeneRIF
Shum et al., Hong Kong, Hong Kong. In J Cell Sci, 2006
The first to identify upregulated CHST1 protein gene expression correlating with the motility of Schwann cells that guide growing axons through both developmental and injured environments.
[The pathogenesis and treatment of corneal disorders].
Review
Kanai, Tokyo, Japan. In Nihon Ganka Gakkai Zasshi, 2002
2. Corneal dystrophy: In corneal dystrophy related to four candidate genes such as transforming growth factor beta-induced(TGFBI) gene, membrane component 1 surface maker 1(M 1 S 1) gene, carbohydrate sulfotransferase gene 6(CHST 6), and collagen type VIII alpha-2(COL8 A 2) gene, 208 Japanese and 42 Vietnamese families were analyzed for the gene mutation and studied for the frequency of gene mutation and differences of clinical features.
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