The Human Hookworm Vaccine.
Houston, United States. In Vaccine, 2013
The candidate vaccine is comprised of two recombinant antigens known as Na-GST-1 and Na-APR-1, each of which is an important parasite enzyme required for hookworms to successfully utilize host blood as a source of energy.
Potency testing for the experimental Na-GST-1 hookworm vaccine.
Washington, D.C., United States. In Expert Rev Vaccines, 2010
Herein, we discuss the evolution of our thinking regarding the design of a potency assay along these newly defined lines and its application to the release of the experimental Necator americanus-glutathione-S- transferase-1 (Na-GST-1) vaccine to prevent human hookworm infection.
The roles of chondroitin-4-sulfotransferase-1 in development and disease.
Chicago, United States. In Prog Mol Biol Transl Sci, 2009
Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units.
[The pathogenesis and treatment of corneal disorders].
Tokyo, Japan. In Nihon Ganka Gakkai Zasshi, 2002
2. Corneal dystrophy: In corneal dystrophy related to four candidate genes such as transforming growth factor beta-induced(TGFBI) gene, membrane component 1 surface maker 1(M 1 S 1) gene, carbohydrate sulfotransferase gene 6(CHST 6), and collagen type VIII alpha-2(COL8 A 2) gene, 208 Japanese and 42 Vietnamese families were analyzed for the gene mutation and studied for the frequency of gene mutation and differences of clinical features.