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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Structural maintenance of chromosomes 2

Cape
Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, NF-kappaB, V1a
Papers using Cape antibodies
Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial
Supplier
Melcher Alan et al., In Molecular Cancer, 2007
... were treated with 2.5 mM 2-aminopurine (2-AP) (Sigma-Aldrich) or 50 μM caffeic acid phenethyl ester (CAPE) (Axxora, Nottingham, UK) for 1 hour ...
BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism
Supplier
Yuan Shengtao et al., In Journal of Experimental & Clinical Cancer Research : CR, 2005
... API-1, SB 202190, PX 12 and Caffeic acid phenethyl ester (CAPE) were from Tocris (Bristol, UK) ...
Papers on Cape
Melatonin and caffeic acid phenethyl ester in the regulation of mitochondrial function and apoptosis: The basis for future medical approaches.
Review
New
Akyol et al., Çorum, Turkey. In Life Sci, Feb 2016
UNASSIGNED: The aim of this review article is to summarize and compare the effects of melatonin and caffeic acid phenethyl ester (CAPE) on the relationship between mitochondrial functioning and apoptosis.
A glucuronoxylomannan-associated immune signature, characterized by monocyte deactivation and raised IL-10, is a predictor of death in cryptococcal meningitis.
New
Meintjes et al., Cape Town, South Africa. In J Infect Dis, Feb 2016
METHODS:  A prospective cohort study was conducted in Cape Town, South Africa.
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells.
New
Shouman et al., Cairo, Egypt. In Oxid Med Cell Longev, Dec 2015
Caffeic acid phenethyl ester (CAPE) is a polyphenolic compound present in many medicinal plants and in propolis.
Temperature and residence time controls on an estuarine harmful algal bloom: Modeling hydrodynamics and Alexandrium fundyense in Nauset estuary.
New
Anderson et al., United States. In Journal 2093-4947, Dec 2015
Nauset estuary on Cape Cod (MA, USA) consists of three salt ponds connected to the ocean through a shallow marsh and network of tidal channels.
Caffeic acid phenethyl ester as a remedial agent for reproductive functions and oxidative stress-based pathologies of gonads.
Review
New
Akyol et al., Ankara, Turkey. In J Intercult Ethnopharmacol, Apr 2015
In recent years, the studies on the roles of caffeic acid phenethyl ester (CAPE) in several disease models and cell cultures are tremendously growing.
Biosafety research for non-target organism risk assessment of RNAi-based GE plants.
Review
Zhou et al., Washington, D.C., United States. In Front Plant Sci, 2014
The use of the RNAi mechanism to develop new traits in plants has fueled a discussion about the environmental safety of the technology for these applications, and this was the subject of a symposium session at the 13th ISBGMO in Cape Town, South Africa.
Caffeic Acid phenethyl ester is a potential therapeutic agent for oral cancer.
Review
Chuu et al., Taiwan. In Int J Mol Sci, 2014
In this review we discuss the possibility of using caffeic acid phenethyl ester (CAPE) as an alternative treatment for oral cancer.
Taxonomy of Colophon Gray (Coleoptera: Lucanidae): new species and a status change.
Strümpher et al., Pretoria, South Africa. In Zootaxa, 2014
Three new species of the Cape high-mountain stag beetle genus, Colophon Gray (Coleoptera: Lucanidae), from South Africa are described.
Taxonomic revision of Phascogale tapoatafa (Meyer, 1793) (Dasyuridae; <br />Marsupialia), including descriptions of two new subspecies and confirmation of P. pirata Thomas, 1904 as a 'Top End' endemic.
Chesser et al., Washington, D.C., United States. In Zootaxa, 2014
A new appraisal of morphological and molecular diversity within the group reveals that the population in the 'Top End' of the Northern Territory is specifically distinct from all others, including those in the Kimberley region of Western Australia to the west and on Cape York of Queensland to the east.
Bioactivity and chemical synthesis of caffeic acid phenethyl ester and its derivatives.
Review
Duan et al., Nanjing, China. In Molecules, 2013
Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on.
RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer.
Impact
O'Shaughnessy et al., Fairfax, United States. In J Clin Oncol, 2011
Before random assignment, investigators chose capecitabine (Cape; 2,000 mg/m(2) for 14 days), taxane (Tax) -based (nab-paclitaxel 260 mg/m(2), docetaxel 75 or 100 mg/m(2)), or anthracycline (Anthra) -based (doxorubicin or epirubicin combinations [doxorubicin/cyclophosphamide, epirubicin/cyclophosphamide, fluorouracil/epirubicin/cyclophosphamide, or fluorouracil/doxorubicin/cyclophosphamide]) chemotherapy administered every 3 weeks.
Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of a human condensin SMC2 hinge domain with short coiled coils.
GeneRIF
Ohkubo et al., Suita, Japan. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2010
human SMC2 hinge domain with short coiled coils was cloned, expressed, purified and crystallized in the orthorhombic space group C222 in native and SeMet-derivatized forms
Streptavidin-Binding Peptide (SBP)-tagged SMC2 allows single-step affinity fluorescence, blotting or purification of the condensin complex.
GeneRIF
Hudson et al., Melbourne, Australia. In Bmc Biochem, 2009
Studies indicate that tagged SMC2 subunit of the condensin complex with the streptavidin-Binding Peptide optimising efficacious use of this tag for protein analysis.
From virus structure to chromatin: X-ray diffraction to three-dimensional electron microscopy.
Impact
Klug, Cambridge, United Kingdom. In Annu Rev Biochem, 2009
I moved to the University of Cape Town to work on the X-ray crystallography of some small organic compounds.
Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma.
GeneRIF
Aozasa et al., Ōsaka, Japan. In Cancer Sci, 2007
mutation analysis of hCAP-C & hCAP-E in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C or hCAP-E heterozygous mutations, indicating condensin mutations are relatively frequent in PAL
Parasitic Cape honeybee workers, Apis mellifera capensis, evade policing.
Impact
Ratnieks et al., Sheffield, United Kingdom. In Nature, 2002
Relocation of the Cape honeybee, Apis mellifera capensis, by bee-keepers from southern to northern South Africa in 1990 has caused widespread death of managed African honeybee, A. m. scutellata, colonies.
A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation.
GeneRIF
Yokomori et al., Irvine, United States. In Mol Cell Biol, 2000
Demonstrates that the human Smc2l1 ortholog, hCAP-E, is a member of the condensin complex that is involved in mitotic chromosome condensation.
Classification of drug-resistant tuberculosis in an epidemic area.
Impact
Van Helden et al., Stellenbosch, South Africa. In Lancet, 2000
METHODS: This descriptive study of 63 patients with drug-resistant tuberculosis assessed the relative contribution of transmission of drug-resistant strains in a high-incidence community of Cape Town, South Africa, by restriction-fragment length polymorphism (RFLP).
Intragranular diffusion: an important mechanism influencing solute transport in clastic aquifers?
Impact
Hearn et al., In Science, 1990
Quantification of intragranular porosity in sand-size material from an aquifer on Cape Cod, Massachusetts, by scanning electron microscopy, mercury injection, and epifluorescence techniques shows that there are more reaction sites and that porosity is greater than indicated by standard short-term laboratory tests and measurement techniques.
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