The lipooligosaccharide-modifying enzyme LptA enhances gonococcal defence against human neutrophils.
Charlottesville, United States. In Cell Microbiol, Jun 2015
(ii) lptA mutant Gc is more sensitive to killing by components found in neutrophil granules, including CAP37/azurocidin, human neutrophil peptide 1 and the serine protease cathepsin G. (iii) lptA mutant Gc is more susceptible to killing by antimicrobial components that are exocytosed from neutrophils, including those decorating neutrophil extracellular traps.
Expression and regulation of antimicrobial peptides in articular joints.
Kiel, Germany. In Ann Anat, 2005
In this review, we focus on the most prominent antimicrobial proteins in articular joints, which we have identified as lysozyme, lactoferrin, secretory phospholipase A2, RNase 7, CAP37, the cathelicidin LL37, and especially the human beta-defensin-2 and -3 (HBD-2/-3).