Madagascar. In Unknown Journal, Sep 2015
Painful DN can be difficult to treat, and is associated with reduced quality of life, poor sleep, depression and anxiety.
Evolutionary and functional perspectives on signaling from neuronal surface to nucleus.
New York City, United States. In Biochem Biophys Res Commun, May 2015
This intricate pathway depends on a specific role for multiple Ca(2+)/CaM-dependent kinases and phosphatases: α/βCaMKII phosphorylates γCaMKII to trap CaM; CaN dephosphorylates γCaMKII to dispatch it to the nucleus; and PP2A induces CaM release from γCaMKII so that CaMKK and CaMKIV can trigger CREB phosphorylation.