CaM Kinases: From Memories to Addiction.
Erlangen, Germany. In Trends Pharmacol Sci, Jan 2016
Ca(2+)/calmodulin-dependent protein kinases (CaMKs) are important Ca(2+) sensors translating glutamatergic activation into synaptic plasticity during learning and memory formation.
Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor.
Jupiter, United States. In Cell, Dec 2015
Activation by a DRD1 agonist produced non-canonical signal transduction via Gαq-PLC-IP3-Ca(2+) at the expense of canonical DRD1 Gαs cAMP signaling to result in CaMKII activation, glutamate receptor exocytosis, synaptic reorganization, and expression of early markers of hippocampal synaptic plasticity.