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proteins. Page last changed on 08 Dec 2016.
Gap junction protein, alpha 8, 50kDa
CAE, Cx50, connexin50, GJA8
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009] (from