Molecular features distinguish ten neuronal types in the mouse superficial superior colliculus.
New Haven, United States. In J Comp Neurol, Jan 2016
Our analysis revealed 12 molecules with distinct expression patterns in mouse sSC: cadherin 7, contactin 3, netrin G2, cadherin 6, protocadherin 20, retinoid-related orphan receptor β, brain-specific homeobox/POU domain protein 3b, Ets variant gene 1, substance P, somatostatin, vasoactive intestinal polypeptide and parvalbumin.
Whole exome sequencing in females with autism implicates novel and candidate genes.
Kansas City, United States. In Int J Mol Sci, 2014
Five females presented with functional variants of X-linked genes (IL1RAPL1, PIR, GABRQ, GPRASP2, SYTL4) with cadherin, protocadherin and ankyrin repeat gene families most commonly altered (e.g., CDH6, FAT2, PCDH8, CTNNA3, ANKRD11).
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
London, United Kingdom. In Nat Genet, 2011
We identified 69 candidate genes, including genes involved in biliary transport (ATP8B1 and ABCB11), glucose, carbohydrate and lipid metabolism (FADS1, FADS2, GCKR, JMJD1C, HNF1A, MLXIPL, PNPLA3, PPP1R3B, SLC2A2 and TRIB1), glycoprotein biosynthesis and cell surface glycobiology (ABO, ASGR1, FUT2, GPLD1 and ST3GAL4), inflammation and immunity (CD276, CDH6, GCKR, HNF1A, HPR, ITGA1, RORA and STAT4) and glutathione metabolism (GSTT1, GSTT2 and GGT), as well as several genes of uncertain or unknown function (including ABHD12, EFHD1, EFNA1, EPHA2, MICAL3 and ZNF827).
Polycomb target genes are silenced in multiple myeloma.
Uppsala, Sweden. In Plos One, 2009
The chromatin modifications were determined at five PRC2 targets commonly underexpressed in multiple myeloma (CIITA, CXCL12, GATA2, CDH6 and ICSBP/IRF8). The selected genes were confirmed to be underexpressed in MM compared to normal plasma cells.
[Molecular and cytometric analysis of renal cell carcinoma cells. Concepts, techniques and prospects].
Saint-Étienne, France. In Prog Urol, 2003
Some of the antigens used for molecular diagnosis of clear cell RCC, such as cadherin-6, are present in the normal kidney, while others are newly formed antigens (TuM2PK, MN/CA9, CA12, calpain) or ectopic (PSMA, PSA, KLKI, cytokeratin 7 vimentin) or induce abnormal glycosylation (sialyl Lewis'X, galectins) indicating the malignant nature of the cells.
Cadherins in renal cell carcinoma.
Berlin, Germany. In Anticancer Res, 1999
Four major cadherins have been demonstrated in normal kidney and renal cell carcinoma: N-cadherin, E-cadherin, ksp-cadherin, and cadherin 6.
[Recent progress of prognostic factors in renal cell carcinoma].
Tsukuba, Japan. In Gan To Kagaku Ryoho, 1998
Recent studies have shown that nuclear morphometry, cell proliferation analyses, (Ki-67 and AgNOR), expression of cell adhesion molecule, (cadherin-6 and alpha-catenin), and protease expression, expression and serum level of growth factors (VEGF and bFGF), might be among the new candidates for a useful prognostic marker.