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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Calcium channel, voltage-dependent, beta 3 subunit

CACNB3, CACNLB3, calcium channel, voltage-dependent, beta 3 subunit, voltage-dependent calcium-channel beta 3 subunit
subunit of a voltage-gated calcium channel that modulates activity of alpha 1 subunits [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: ACID, SET, iNOS, PCNA, Phospho
Papers on CACNB3
Calcium channel genes associated with bipolar disorder modulate lithium's amplification of circadian rhythms.
New
Welsh et al., San Diego, United States. In Neuropharmacology, Feb 2016
Longitudinal expression of LTCC genes (CACNA1C, CACNA1D and CACNB3) was then measured over 12-24 h in BD and control cells.
Binding loci of RelA-containing nuclear factor-kappaB dimers in promoter regions of PHM1-31 myometrial smooth muscle cells.
New
Chapman et al., Sheffield, United Kingdom. In Mol Hum Reprod, Nov 2015
In unstimulated PHM1-31 cells, anti-RelA-serum-enriched regions were associated with sequences corresponding to open reading frames of ion channel subunit genes including CACNB3 and KCNB1.
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.
New
Haggarty et al., Boston, United States. In Mol Psychiatry, May 2015
Of the predicted miR-34a targets, we validated the BD risk genes ankyrin-3 (ANK3) and voltage-dependent L-type calcium channel subunit beta-3 (CACNB3) as direct miR-34a targets.
Up-regulation of Cavβ3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain.
GeneRIF
Pan et al., Houston, United States. In J Biol Chem, 2012
Cavbeta(3) subunit at the spinal level represents an effective strategy for treating neuropathic pain
Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model.
Potter et al., Minneapolis, United States. In Clin Cancer Res, 2011
RESULTS: Four genomic markers, DBN1 (drebrin 1), CACNB3 (calcium channel beta 3), FLAD1 (PP591; flavin adenine dinucleotide synthetase), and CCND2 (cyclin D2), exhibited highly significant differential expression in recurrent tumors in the training set (P < 0.001).
Molecular determinants of the CaVbeta-induced plasma membrane targeting of the CaV1.2 channel.
GeneRIF
Parent et al., Köln, Germany. In J Biol Chem, 2010
a model where high affinity binding of Ca(V)beta to the I-II linker of Ca(V)alpha1 largely accounts for Ca(V)beta-induced plasma membrane targeting of Ca(V)1.2
The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6.
GeneRIF
Yang et al., New York City, United States. In J Biol Chem, 2010
in the presence of Pax6(S), beta(3) is translocated from the cytoplasm to the nucleus;full-length Ca(v)beta may act directly as a transcription regulator independent of its role in regulating Ca(2+) channel activity
Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4.
GeneRIF
Engel et al., Tübingen, Germany. In Channels (austin), 2009
neither Ca(V)beta3 nor Ca(V)beta4 are indispensable for hair cell Ca(2+) currents but contribute to the overall current properties
Upregulation of N-acetylaspartic acid alters inflammation, transcription and contractile associated protein levels in the stomach and smooth muscle contractility.
Surendran, Houston, United States. In Mol Biol Rep, 2009
Incubation of rat stomach tissue with NAA 1.5 mM, 1.5 microM and 1.5 nM induced inflammatory agents TNFalpha, p38MAPK, iNOS, PKC, COX2 and ICAM3; transcription factors phospho-NF-kBp65, cjun and cfos; contractile proteins MLCK and phospho MLC; and calcium channel alpha1C and calcium channel, voltage-dependent, beta 3 subunit compared to their respective control.
Expression and function of the gene encoding the voltage-dependent calcium channel beta3-subunit in the mouse placenta.
Fundele et al., Uppsala, Sweden. In Placenta, 2007
There are four genes encoding CACNB subunits and the gene encoding CACNB3 is over expressed in hyperplastic placentas of mouse interspecies hybrids.
RGK small GTP-binding proteins interact with the nucleotide kinase domain of Ca2+-channel beta-subunits via an uncommon effector binding domain.
GeneRIF
Hunziker et al., Singapore, Singapore. In J Biol Chem, 2007
docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP to guanylate kinase
Exclusion of 5 functional candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3.
Timmerman et al., Antwerp, Belgium. In Ann Hum Genet, 2001
Here, we report the mutation analysis of five other candidate genes localised within the distal HMN II region: the cytoskeletal proteins paxillin (PXN) and restin (RSN); the acidic ribosomal phosphoprotein, large P0 subunit (RPLP0); a nucleoside diphosphate kinase (NME2B); and the beta 3 subunit of the voltage-gated calcium channel (CACNB3).
Microarray analysis of hippocampal gene expression in global cerebral ischemia.
Greenberg et al., Novato, United States. In Ann Neurol, 2001
We also found coinduction of several groups of related genes that might represent functional modules within the ischemic neuronal transcriptome, including VEGF and its receptor, NRP1; the IGF1 receptor and the IGF1-binding protein IGFBP2; Rb, the Rb-binding protein E2F1, and the E2F-related transcription factor, TFDP1; the CACNB3 and CACNB4 beta-subunits of the voltage-gated calcium channel; and caspase-3 and its substrates, ACINUS, FEM1, and GSN.
The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.
Seino et al., Kyoto, Japan. In Genomics, 1995
We have determined the structures of the human CACN4 (CACNL1A2) and the human beta 3 (CACNLB3) genes.
Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit.
Nargeot et al., Montpellier, France. In Eur J Biochem, 1994
A novel human-voltage-dependent-calcium-channel (VDCC) beta subunit was isolated from a 9-week-old human total-embryo cDNA library.
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