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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

C1q and tumor necrosis factor related protein 6

Top mentioned proteins: V1a, ACID, PTPN22, AGE, CAN
Papers on C1QTNF6
[C1q tumor necrosis factor-related protein 6 (CTRP6) inhibits the proliferation and migration of ovarian cancer cells].
Sun et al., Xi'an, China. In Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, Dec 2015
Objective To explore the role of C1q tumor necrosis factor-related protein 6 (CTRP6) in the proliferation and migration of ovarian cancer cells.
Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study.
Rønningen et al., Oslo, Norway. In Viral Immunol, Dec 2015
The most significant association was with two T1D SNPs, rs12150079 (ZPBP2/ORMDL3/GSDMB region) (enterovirus frequency: AA 7.3%, AG 8.7%, GG 9.7%, RR = 0.86, overall p = 1.87E-02) and rs229541 (C1QTNF6/SSTR3/RAC2) (enterovirus frequency: CC 7.8%, CT 9.7%, TT 9.4%, RR = 1.13, overall p = 3.6E-02), followed by TLR8 (rs2407992) (p = 3.8E-02), TLR3 (1914926) (p = 4.9E-02), and two other T1D SNPs (IFIH1 rs3747517, p = 4.9E-02 and PTPN22, rs2476601, p = 5.3E-02).
Knockdown of CTRP6 inhibits adipogenesis via lipogenic marker genes and Erk1/2 signalling pathway.
Yang et al., China. In Cell Biol Int, May 2015
C1q/tumor necrosis factor-related protein 6 (CTRP6), an adipose-tissue secretory factor, plays an important role in inflammatory reaction and carcinogenesis.
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation.
Wu et al., Beijing, China. In Basic Res Cardiol, 2014
C1q/tumor necrosis factor-related protein-6 (CTRP6) is a newly identified adiponectin paralog with modulation effects on metabolism and inflammation.
CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.
Iwakura et al., Chiba, Japan. In Nat Commun, 2014
Here we show that C1q/TNF-related protein 6 (CTRP6; gene symbol C1qtnf6) expression is elevated in mouse rheumatoid arthritis (RA) models.
Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.
China Consortium for the Genetics of Autoimmune Thyroid Disease et al., Shanghai, China. In Hum Mol Genet, 2013
In this study, we carried out a three-stage study in 9529 patients with GD and 9984 controls to identify new risk loci for GD and found genome-wide significant associations in the overall populations for five novel susceptibility loci: the GPR174-ITM2A at Xq21.1, C1QTNF6-RAC2 at 22q12.3-13.1,
Evidence of stage- and age-related heterogeneity of non-HLA SNPs and risk of islet autoimmunity and type 1 diabetes: the diabetes autoimmunity study in the young.
Norris et al., Aurora, United States. In Clin Dev Immunol, 2012
C1QTNF6 (rs229541) predicted increased IA risk (HR: 1.57, CI: 1.20-2.05)
A combined approach identifies three mRNAs that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7.
Wang et al., Nanjing, China. In J Cancer Res Clin Oncol, 2012
We further confirmed the activities of three target genes, C1QTNF6, SPARC, and COL4A2, by luciferase reporter analyses and invasion assays.
Cross-contamination of a UROtsa stock with T24 cells--molecular comparison of different cell lines and stocks.
Dopp et al., Bochum, Germany. In Plos One, 2012
DNA methylation of RARB, PGR, RASSF1, CDH1, FHIT, ESR1, C1QTNF6, PTGS2, SOCS3, MGMT, and LINE1 was analyzed by pyrosequencing and compared with results from the cell lines RT4, T24, HeLa, BEAS-2B, and HepG2.
Depletion of mitochondrial DNA stabilizes C1qTNF-related protein 6 mRNA in muscle cells.
Park et al., Kyŏngju, South Korea. In J Korean Med Sci, 2012
Recently, we demonstrated that C1qTNF-related protein-6 (CTRP6) is involved in fatty acid metabolism in muscle cells.
Expression of a secretory protein C1qTNF6, a C1qTNF family member, in hepatocellular carcinoma.
Nagayama et al., Kōchi, Japan. In Anal Cell Pathol (amst), 2010
C1qTNF6 is overexpressed and possibly contributes to tumor angiogenesis by activating the Akt pathway in many hepatocellular carcinomas.
Epigenetic modification of retinoic acid-treated human embryonic stem cells.
Shin et al., Seoul, South Korea. In Bmb Rep, 2010
Combined analysis of methylation and expression data revealed that 19 genes (STAP2, VAMP8, C10orf26, WFIKKN1, ELF3, C1QTNF6, C10orf10, MRGPRF, ARSE, LSAMP, CENTD3, LDB2, POU5F1, GSPT2, THY1, ZNF574, MSX1, SCMH1, and RARB) were highly correlated with each other.
C1qTNF-related protein-6 increases the expression of interleukin-10 in macrophages.
Park et al., South Korea. In Mol Cells, 2010
However, the functional role of CTRP6 remains poorly identified.
Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
Spritz et al., Aurora, United States. In N Engl J Med, 2010
UBASH3A (P=1.26x10(-9)), and C1QTNF6 (P=2.21x10(-16)).
C1qTNF-related protein-6 mediates fatty acid oxidation via the activation of the AMP-activated protein kinase.
Park et al., South Korea. In Febs Lett, 2010
CTRP6 plays a role in fatty acid metabolism via the AMPK-ACC pathway. The globular domain of CTRP6 mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase (AMPK) in skeletal muscle cells.
Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.
Barton et al., Manchester, United Kingdom. In Arthritis Res Ther, 2009
A marker at one other locus, C1QTNF6, previously associated with T1D, showed nominal association with RA in the current study but did not remain statistically significant at the corrected threshold.
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
Todd et al., Cambridge, United Kingdom. In Nat Genet, 2008
We obtained further support for 4q27 (IL2-IL21, P = 1.9 x 10(-8)) and, after genotyping an additional 6,225 cases, 6,946 controls and 2,828 families, convincing evidence for four previously unknown and distinct risk loci in chromosome regions 6q15 (BACH2, P = 4.7 x 10(-12)), 10p15 (PRKCQ, P = 3.7 x 10(-9)), 15q24 (CTSH, P = 3.2 x 10(-15)) and 22q13 (C1QTNF6, P = 2.0 x 10(-8)).
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