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DENN/MADD domain containing 4A

c-myc promoter binding protein 1, IRLB, as a c-Myc promoter binding protein
Top mentioned proteins: c-Myc, MBP, Phosphopyruvate Hydratase, V1a, Miz-1
Papers on c-myc promoter binding protein 1
Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis.
Yeh et al., In Carcinogenesis, 2014
c-Myc promoter binding protein 1 (MBP-1) is a negative regulator of c-myc expression and ubiquitously expressed in normal human tissues.
MBP-1 suppresses growth and metastasis of gastric cancer cells through COX-2.
Yeh et al., Taipei, Taiwan. In Mol Biol Cell, 2009
The c-Myc promoter binding protein 1 (MBP-1) is a transcriptional suppressor of c-myc expression and involved in control of tumorigenesis.
The activated Notch1 receptor cooperates with alpha-enolase and MBP-1 in modulating c-myc activity.
Yeh et al., Taipei, Taiwan. In Mol Cell Biol, 2008
Here we demonstrated that N1IC interacted with the c-Myc-regulating proteins alpha-enolase and c-myc promoter binding protein 1 (MBP-1).
The kelch protein NS1-BP interacts with alpha-enolase/MBP-1 and is involved in c-Myc gene transcriptional control.
Giallongo et al., Palermo, Italy. In Biochim Biophys Acta, 2007
The MBP-1 protein has been characterized as a c-Myc promoter binding protein that negatively controls transcription.
Differential expression of the human alpha-enolase gene in oral epithelium and squamous cell carcinoma.
Nohno et al., Kurashiki, Japan. In Cancer Sci, 2007
alpha-Enolase and c-myc promoter binding protein 1 are encoded by a single gene, ENO1, and are synthesized from the same transcript through alternative use of translational start sites.
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2.
Carroll et al., New York City, United States. In Cancer, 2004
METHODS: Transient reporter assays and trichostatin A (TSA) experiments were performed to evaluate several candidate genes, including Mxi1, c-myc promoter binding protein 1 (MBP-1), Miz, and histone deacetylase 2 (HDAC2), for their involvement in N-myc autoregulation.
Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.
Semov et al., Moscow, Russia. In Genomics, 2003
IRLB was originally identified as a partial cDNA clone, encoding a 191-aa protein binding the interferon-stimulated response element (ISRE) in the P2 promoter of human MYC.
Microarray analysis of E-box binding-related gene expression in young and replicatively senescent human fibroblasts.
Wang et al., Montréal, Canada. In Anal Biochem, 2002
Moreover, quiescence and senescence can be distinguished by increased expression of Irlb, c-Myc transcription factor, and Miz-1, c-Myc-interacting Zn finger protein 1, only in the former state.
Functional domains of c-myc promoter binding protein 1 involved in transcriptional repression and cell growth regulation.
Ray et al., Saint Louis, United States. In Mol Cell Biol, 1999
We initially identified c-myc promoter binding protein 1 (MBP-1), which negatively regulates c-myc promoter activity, from a human cervical carcinoma cell expression library.
Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element.
Kisselev et al., Moscow, Russia. In Gene, 1994
A human cDNA clone encoding a c-myc promoter-binding protein (IRLB) was selected by screening a human fibroblast lambda gt11 phage library with the hexamer oligodeoxyribonucleotide (oligo) 5'-GGCGGGAAAAAGAACGGA, corresponding to the protein-binding element of human c-myc similar to the interferon-stimulated response element (ISRE).
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