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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Vesicle-associated membrane protein 5

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, Phosphodiesterase, V1a
Papers on c-AMP
Stimulation of angiogenesis by cilostazol accelerates fracture healing in mice.
Histing et al., Homburg, Germany. In J Orthop Res, Dec 2015
Cilostazol, a selective phosphodiesterase-3 inhibitor, is known to control cyclic adenosine monophosphate (c-AMP) and to stimulate angiogenesis through upregulation of pro-angiogenic factors.
Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens.
Andersen et al., United States. In Regul Toxicol Pharmacol, Oct 2015
Ontology analysis of the 1026 V2O5 differentially expressed genes showed enrichment for hyaluronan and sphingolipid metabolism, adenylate cyclase functions, c-AMP signaling and PKA activation/signaling. Enrichment of lipids/lipoprotein metabolism and inflammatory pathways were consistent with previously reported clinical findings.
PRKX, a Novel cAMP-Dependent Protein Kinase Member, Plays an Important Role in Development.
Li et al., Chengdu, China. In J Cell Biochem, Sep 2015
UNASSIGNED: The human protein kinase X gene (PRKX) and cAMP-dependent protein kinase (PKA) are both c-AMP-dependent serine/threonine protein kinases within the protein kinase AGC subgroup.
Bacterial signal transduction by c-di-GMP and other nucleotide second messengers.
Yildiz et al., London, United Kingdom. In J Bacteriol, Jul 2015
While the focus was on signal input, synthesis, degradation and the striking diversity of the modes of action of the current second messenger paradigm, i.e. c-di-GMP, also 'classics' like cAMP and (p)ppGpp were presented in novel facets and more recent 'newcomers' such as c-di-AMP and c-AMP-GMP made an impressive appearance.
Control of bacterial exoelectrogenesis by c-AMP-GMP.
Breaker et al., New Haven, United States. In Proc Natl Acad Sci U S A, May 2015
Recently, another second messenger dinucleotide, c-AMP-GMP, was found to control chemotaxis and colonization by Vibrio cholerae.
Serotonin2C receptor stimulation inhibits cocaine-induced Fos expression and DARPP-32 phosphorylation in the rat striatum independently of dopamine outflow.
Spampinato et al., Bordeaux, France. In Neuropharmacology, Feb 2015
Conversely, Ro 60-0175 inhibited cocaine-induced Fos immunoreactivity and phosphorylation of the DA and c-AMP regulated phosphoprotein of Mr 32 kDa (DARPP-32) at threonine 75 residue in the striatum.
Standardization of a bioassay for thyrotropin receptor stimulating autoantibodies.
Kahaly et al., Mainz, Germany. In Thyroid, Feb 2015
METHODS: Serum TSAb activity was measured with a FDA-cleared bioassay that utilizes CHO cells expressing a chimeric thyrotropin receptor (TSHR) and a c-AMP response-element-dependent luciferase.
Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.
Csernansky et al., Chicago, United States. In Psychopharmacology (berl), 2014
The effect of CRF1 on Aβ1-42 levels was also diminished by treatment with H-89, a c-AMP/PKA inhibitor.
Anti-melanogenic activity of the novel herbal medicine, MA128, through inhibition of tyrosinase activity mediated by the p38 mitogen-activated protein kinases and protein kinase signaling pathway in B16F10 cells.
Ma et al., Taejŏn, South Korea. In Pharmacogn Mag, 2014
Using western blotting, expression levels of tyrosinase, tyrosinase-related protein-1 (TRP-1), TRP-2, microphthalmia-associated transcription factor (MITF), and activation of c-AMP-dependent protein kinase (PKA), c-AMP-related element binding protein (CREB) and mitogen-activated protein kinases (MAPKs) were examined.
Large-scale identification of phosphorylation sites for profiling protein kinase selectivity.
Ishihama et al., Kyoto, Japan. In J Proteome Res, 2014
For this purpose, we employed a combination strategy of in vitro kinase reaction followed by LC-MS/MS analysis and applied it to three well-studied kinases: c-AMP regulated protein kinase A (PKA), extracellular signal-regulated kinase 1 (ERK1), and RAC-alpha serine/threonine-protein kinase (AKT1).
Fluxes of lactate into, from, and among gap junction-coupled astrocytes and their interaction with noradrenaline.
Dienel et al., Shenyang, China. In Front Neurosci, 2013
Receptor-mediated effects of lactate on locus coeruleus neurons include noradrenaline release in cerebral cortex and c-AMP-mediated stimulation of astrocytic gap junctional coupling, thereby enhancing its dispersal and release from brain.
Lycopene modulates THP1 and Caco2 cells inflammatory state through transcriptional and nontranscriptional processes.
Serge et al., Marseille, France. In Mediators Inflamm, 2013
Lycopene enhanced MMP9 secretion via a c-AMP-dependent process, and reduced ROS production at higher concentrations than 2 μM.
Cyclic di-nucleotide signaling enters the eukaryote domain.
Schaap, Dundee, United Kingdom. In Iubmb Life, 2013
However, additional functions for c-di-GMP and roles for related molecules, such as c-di-AMP and c-AMP-GMP continue to be uncovered.
Aromatherapy and the central nerve system (CNS): therapeutic mechanism and its associated genes.
Tzeng et al., Xiamen, China. In Curr Drug Targets, 2013
These have mainly centered on possible deficiencies in monoamines, neurotrophins, the neuroendocrine system, c-AMP, cation channels as well as neuroimmune interactions and epigenetics, however the precise mechanism or mechanisms related to depression have yet to be elucidated.
Second line therapy: type 2 diabetic subjects failing on metformin GLP-1/DPP-IV inhibitors versus sulphonylurea/insulin: for GLP-1/DPP-IV inhibitors.
Kumar, Patna, India. In Diabetes Metab Res Rev, 2012
They owe this property to their binding with G-Protein-coupled receptors leading to an increased amount of c-AMP.
Effects of contraction on localization of GLUT4 and v-SNARE isoforms in rat skeletal muscle.
Richter et al., Copenhagen, Denmark. In Am J Physiol Regul Integr Comp Physiol, 2009
VAMP2, VAMP5, and VAMP7 may be involved in translocation of GLUT4 during muscle contractions.
VAMP5 and VAMP8 are most likely not involved in primary open-angle glaucoma.
Bergen et al., Amsterdam, Netherlands. In Mol Vis, 2004
Our findings indicate that VAMP5 and VAMP8 are not involved in POAG in the Dutch population.
The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network.
Hong et al., Singapore, Singapore. In J Biol Chem, 2003
The cytoplasmic domain of this protein is responsible for its correct subcellular targeting.
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