Structural considerations of autoantibodies.
Philadelphia, United States. In Lupus, 2001
The mechanisms responsible for peptide-induced immunosuppression lupus-prone BWF1 mice were determined to be mediated via recognition by T cells, although the response was peptide-specific, as some accelerated the autoimmune response.
Lessons from the NZM2410 model and related strains.
Gainesville, United States. In Int Rev Immunol, 1999
The main advantages presented by this strain over other models are the genetic homozygozity at all loci and an highly penetrant early onset lupus nephritis in both males and females, indicating that the strongest BWF1 susceptibility loci were retained in NZM2410.