Analysis of chromatin structure of genes silenced by heterochromatin in trans.
Pittsburgh, United States. In Genetics, 2008
An insertion of heterochromatic satellite DNA in the euchromatic brown (bw) gene of Drosophila melanogaster results in bwDominant (bwD), which can inactivate loci on the homolog by relocation near the centric heterochromatin (trans-inactivation). Nucleosomal compaction was found to accompany trans-inactivation, but stereotypical heterochromatic histone modifications were mostly absent on silenced reporter genes.
Alternative splicing in C. elegans.
Santa Cruz, United States. In Wormbook, 2004
Factors involved in alternative splicing that are discussed include mec-8, smu-1, smu-2, fox-1, exc-7 and unc-75.