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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Beta-transducin repeat containing

Top mentioned proteins: Ubiquitin, CAN, miR, HAD, SET
Papers on BTRC
EBV-miR-BART10-3p facilitates epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC.
Li et al., Changsha, China. In Oncotarget, Jan 2016
In this study, we revealed that in NPC cells, EBV-miR-BART10-3p directly targets BTRC gene that encodes βTrCP (beta-transducin repeat containing E3 ubiquitin protein ligase).
Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for FOXC1 in Patients with Coarctation of the Aorta.
Le Caignec et al., Nantes, France. In Circ Cardiovasc Genet, Jan 2016
We identified 113 candidate genes for CHD within these CNVs, including BTRC, CHRNB3, CSRP2BP, ERBB2, ERMARD, GLIS3, PLN, PTPRJ, RLN3 and TCTE3.
Targeted imputation of sequence variants and gene expression profiling identifies twelve candidate genes associated with lactation volume, composition and calving interval in dairy cattle.
Hayes et al., Australia. In Mamm Genome, Dec 2015
There was statistical support for imputed sequence variants in or close to BTRC, MGST1, SLC37A1, STAT5A, STAT5B, PAEP, VDR, CSF2RB, MUC1, NCF4, and GHDC associated with milk production, and EPGN for calving interval.
Effect of TP53 16-bp and β-TrCP 9-bp INS/DEL polymorphisms in relation to risk of breast cancer.
Hashemi et al., Zāhedān, Iran. In Gene, Oct 2015
BTRC gene (Homo sapiens beta-transducing repeat containing E3 ubiquitin protein ligase) encoded protein, β-TrCP, is a novel regulator of p53.
[Analysis of genomic copy number variation for a Chinese patient with split hand/split foot malformation].
Du et al., Wenzhou, China. In Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2014
(102 955 122-103 348 688), which has encompassed genes including LBX1, BTRC and POLL.
Genome-wide association study of growth traits in the Jinghai Yellow chicken.
Wang et al., Yangzhou, China. In Genet Mol Res, 2014
Three proximal genes (BTRC, NLK, and NF1) were found to participate in the Wnt-signaling pathway and mitogen-activated protein kinase signaling pathway.
Interaction of Wnt pathway related variants with type 2 diabetes in a Chinese Han population.
Lu et al., Beijing, China. In Peerj, 2014
The haplotype TGC constructed by TCF7L2 (rs7903146), DKK1 (rs2241529) and BTRC (rs4436485) showed a significant association with T2D (OR = 0.750, 95% CI [0.579-0.972],
Reconstructing the coding and non-coding RNA regulatory networks of miRNAs and mRNAs in breast cancer.
Chen et al., Nanjing, China. In Gene, 2014
Finally, after verified by test sets, three indexes, including area under the ROC curve (AUC), Accuracy and Matthews correlation coefficients (MCCs), indicated only 4 modules (miR-106b-CIT-KPNA2-miR-93, miR-106b-POLQ-miR-93, miR-107-BTRC-UBR3-miR-16 and miR-200c-miR-16-EIF2B5-miR-15b) had discriminated ability and their classification performance were prior to that of the single molecules.
WNT1 gene expression alters in heterogeneous population of prostate cancer cells; decreased expression pattern observed in CD133+/CD44+ prostate cancer stem cell spheroids.
Oktem et al., Manisa, Turkey. In J Buon, 2014
The expression levels of WNT1, FZD1, ADAR, APC, AXIN, BTRC, FRAT1 and PPARD genes were measured by polymerase chain reaction (PCR) array assay and the protein expression levels of WNT1, FZD and AXIN by immunohistochemistry. RESULTS: The expression levels of WNT pathway-related molecules were found to increase in both CSCs and non- CSCs when CSCs were maintained as spheroids.
Genome-wide SNP analysis of the Systemic Capillary Leak Syndrome (Clarkson disease).
Druey et al., Bethesda, United States. In Rare Dis, 2014
Top case-associated SNPs were observed in BTRC (rs12355803, 3rs4436485), ARHGEF18 (rs11668246), CDH13 (rs4782779), and EDG2 (rs12552348), which encode proteins with known or suspected roles in B cell function and/or vascular integrity.
MEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancer.
Sun et al., Shanghai, China. In Febs Lett, 2014
Mechanistically, inhibition of MEK1 by both PD98059 and U0126 as well as RNAi reduces beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC), which acts as a potential endogenous YAP protector.
Global epigenetic regulation of microRNAs in multiple myeloma.
Ghobrial et al., Boston, United States. In Plos One, 2013
Demethylation or gain of function studies of these specific miRNAs led to induction of apoptosis and inhibition of proliferation as well as down-regulation of putative oncogene targets of these miRNAs such as DNMT1, E2F3, BTRC and MYCBP.
Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer.
Sun et al., Shanghai, China. In Hepatology, 2013
By contrast, YAP promotes protein stabilization of CREB through interaction with mitogen-activated protein kinase 14 (MAPK14/p38) and beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC).
A genome-wide survey of photoreceptor and circadian genes in the coral, Acropora digitifera.
Satoh et al., Okinawa, Japan. In Gene, 2013
We also found the following A. digitifera orthologs to Drosophila and mammalian circadian clock genes: four clock, one bmal/cycle, three pdp1-like, one creb/atf, one sgg/zw3, two ck2alpha, one dco (csnk1d/cnsk1e), one slim/BTRC, and one grinl.
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
Inazawa et al., Tokyo, Japan. In Plos One, 2012
Among the candidates, we successfully identified CCNE1, CDC25A, CCND3, CDK4, and BTRC as direct targets for miR-497 and miR-195.
Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons.
Harper et al., Boston, United States. In J Biol Chem, 2008
postsynaptic RapGAP SPAR is regulated by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons.
The role of [beta]-transducin repeat-containing protein ([beta]-TrCP) in the regulation of NF-[kappa]B in vascular smooth muscle cells.
Hall et al., Minneapolis, United States. In Arterioscler Thromb Vasc Biol, 2004
Crosstalk between the Wnt cascade and NF-kappaB signaling in vascular smooth muscle cells is mediated through the E3-ligase, beta-TrCP1, which increases IkappaBalpha degradation.
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