Matrix-based three-dimensional culture of buffalo mammary epithelial cells showed higher induction of genes related to milk protein and fatty acid metabolism.
Karnāl, India. In Cell Biol Int, Feb 2016
The expression of milk casein genes viz., alpha S1-casein (CSN1S1), alpha S2-casein (CSN1S2), beta-casein (CSN2), kappa-casein (CSN3); and fatty acid metabolism genes viz., butyrophilin (BTN1A1), glycerol-3-phosphate acyltransferase (GPAM), fatty acid-binding protein 3 (FABP3), and stearoyl-CoA desaturase (SCD) was assessed in 3D culture in comparison to traditional monolayer culture using qRT-PCR.
Regulation of Immunity by Butyrophilins.
Cambridge, United Kingdom. In Annu Rev Immunol, Feb 2016
UNASSIGNED: Butyrophilin molecules (commonly contracted to BTN), collectively take their name from the eponymous protein in cow's milk.
TROP-2 expression in papillary thyroid carcinoma: Potential Diagnostic Utility.
Atlanta, United States. In Diagn Cytopathol, Jan 2016
Immunohistochemical (IHC) evaluation for TROP-2 was performed on 137 thyroid fine needle aspiration (FNA) cell blocks (CB) which included classic PTC (64), follicular variant PTC (FVPTC) (10), anaplastic thyroid carcinoma (AC) (2), medullary carcinoma (MC) (8), follicular neoplasms (FN) (8), Hurthle cell neoplasms (HCN) (9), follicular lesion of uncertain significance (FLUS) (12), and benign thyroid nodule (BTN) (24).
Biotinylated heptapeptides substituted with a D-amino acid as platelet-activating factor inhibitors.
Iwaki, Japan. In Eur J Pharmacol, Nov 2015
In this study, synthetic heptapeptides (Lys-Trp-Tyr-Lys-Asp-Gly-Asp) coupled to a biotin molecule through the N-terminal amino group and ε-amino group of N-terminus Lys, (Btn)KP6 and K(Btn)P6, respectively, and their biotinylated peptides substituted with D-Lys at the N-terminus, (Btn)dKP6 and dK(Btn)P6, respectively, were investigated for their effects on PAF-induced inflammation.
Butyrophilins: an emerging family of immune regulators.
London, United Kingdom. In Trends Immunol, 2012
This review addresses each of these issues, concluding with the attractive potential of Btn and Btnl molecules to act as specific attenuators of tissue-associated inflammatory responses.