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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Kruppel-like factor 9

BTEB, KLF9, BTEB1, Kruppel-like factor 9
The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: SP1, HAD, CAN, KLF13, V1a
Papers on BTEB
Endometriosis Located Proximal to or Remote From the Uterus Differentially Affects Uterine Gene Expression.
New
Taylor et al., New Haven, United States. In Reprod Sci, Feb 2016
The expression of several genes that are involved in endometrial receptivity (homeobox A10 [Hoxa10], homeobox A11 [Hoxa11], insulin-like growth factor binding protein 1 [Igfbp1], Kruppel-like factor 9 [Klf9], and progesterone receptor [Pgr]) was measured in the eutopic endometrium of mice transplanted with either proximal or distal endometriosis lesions.
Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats.
New
Wood et al., United States. In Endocrinology, Dec 2015
In contrast to small PTU-induced reductions in basal expression of several genes, developmental PTU treatment dramatically reduced the activity-dependent expression of neurotrophins and related genes (Bdnft, Bdnfiv, Arc, Klf9) in adulthood and was accompanied by deficits in hippocampal-based learning.
C2H2 zinc finger proteins of the SP/KLF, Wilms tumor, EGR, Huckebein, and Klumpfuss families in metazoans and beyond.
New
Grishin et al., Dallas, United States. In Gene, Dec 2015
The last ancestor of jawed vertebrates was inferred to have at least 18 KLFs (group A: KLF1/2/4/17, group B: KLF3/8/12; group C: KLF5/5l; group D: KLF6/7; group E: KLF9/13/16; group F: KLF10/KLF11; group G: KLF15/15l) and 10 SPs (group A: SP1/2/3/4; group B: SP5/5l; group C: SP6/7/8/9), since they were found in both cartilaginous and boned fishes.
Involvement of Kruppel-like factor 9 in bleomycin-induced pulmonary toxicity.
New
Yin et al., Changchun, China. In Mol Med Report, Oct 2015
The ROS level, cell death assay, protein and gene expression levels of Kruppel‑like factor 9 (Klf9) and other associated factors were assessed.
Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling.
New
Simmen et al., Little Rock, United States. In Carcinogenesis, Sep 2015
UNLABELLED: Expression of the transcription factor Krüppel-like factor 9 (KLF9) is frequently reduced in colorectal cancers, although a tumor suppressive role has not been established.
Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis.
New
Simmen et al., Little Rock, United States. In Biol Reprod, Jun 2015
Krüppel-like Factor (KLF) 13 and the closely related KLF9 are members of the Sp/KLF family of transcription factors that have collectively emerged as essential regulators of tissue development, differentiation, proliferation, and programmed cell death.
Krüppel-like factors in hepatocellular carcinoma.
Review
New
Ma et al., Shanghai, China. In Tumour Biol, Feb 2015
To date, five members (KLF4, KLF6, KLF8, KLF9, and KLF17) in the KLF family have been reported to function in the pathogenesis of HCC in multiple ways, which hold the potential of deepening and widening our understanding in the initiation and progression of HCC.
CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case-control study.
Li et al., Beijing, China. In Arthritis Res Ther, 2014
Of these, four genes (SOCS3, CBL, IFNAR1, and PIK3CA) were involved in STAT3 (signal transducer and activator of transcription 3) signaling, and three genes (CBL, KLF9, and CSNK2A1) were involved in the Wnt signaling pathway.
Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Folliculogenesis: Integrated Transcriptomic Study and Molecular Signature of Early Follicular Growth.
Mandon-Pepin et al., France. In Plos One, 2014
The expression of genes such as Kruppel-like factor 9 (KLF9) and BMP binding endothelial regulator (BMPER) was highlighted for the first time during early follicular development, and their proteins were also predicted to be involved in gene regulation.
MicroRNA-570 promotes lung carcinoma proliferation through targeting tumor suppressor KLF9.
Liu et al., Shenyang, China. In Int J Clin Exp Pathol, 2014
At the molecular level, krüppel-like factor 9 (KLF9), a tumor suppressor gene, was identified as a potential target of miR-570 in lung cancer cells.
Krüppel-like factor 9 is a circadian transcription factor in human epidermis that controls proliferation of keratinocytes.
GeneRIF
Kramer et al., Hamburg, Germany. In Proc Natl Acad Sci U S A, 2012
Klf9 affects keratinocyte proliferation/differentiation by controlling the expression of target genes in a daytime-dependent manner.
The T3-induced gene KLF9 regulates oligodendrocyte differentiation and myelin regeneration.
GeneRIF
Barres et al., Stanford, United States. In Mol Cell Neurosci, 2012
KLF9 is an integral component of the T3-driven signaling cascade that promotes myelin regeneration.
Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis.
GeneRIF
Simmen et al., Little Rock, United States. In J Clin Endocrinol Metab, 2012
Loss of KLF9 coregulation of endometrial stromal progesterone receptor-responsive gene networks may underlie progesterone resistance in endometriosis.
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Impact
GeneRIF
Tanaka et al., Yokohama, Japan. In Nat Genet, 2012
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells.
GeneRIF
Nikiforov et al., Buffalo, United States. In Blood, 2012
Data identify KLF9 as a novel and potentially clinically relevant transcriptional regulator of drug-induced apoptosis in multiple myeloma cells.
The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues.
Review
Simmen et al., Little Rock, United States. In J Endocrinol, 2010
In this review, we focus on recently described mechanisms of actions of several KLFs (KLF4, KLF5, KLF6, and KLF9) in cancers of the mammary gland and uterus.
[BTEB/KLF9 and its transcriptional regulation].
Review
Lai et al., Hangzhou, China. In Yi Chuan, 2007
BTEB/KLF9(basic transcription element-binding protein/Krüppel-like transcription factor 9), a member of Krüppel-like transcriptional factors, is a zinc finger protein involved in regulating gene transcription in eukaryocyte.
Brain regions and genes affecting postural control.
Review
Strazielle et al., Rouen, France. In Prog Neurobiol, 2007
With the gene deletion technique in mice, specific genes expressed in cerebellum encoding glutamate receptors (Grid2 and Grm1) and other molecules (Prkcc, Cntn6, Klf9, Syt4, and En2) have also been shown to affect postural control.
Significance of the transcription factor KLF5 in cardiovascular remodeling.
Review
Manabe et al., Tokyo, Japan. In J Thromb Haemost, 2005
We previously isolated KLF5/basic transcription element-binding (BTEB)2, a Krüppel-like factor, as a transcription factor that binds the promoter of the embryonic smooth muscle myosin heavy chain gene (SMemb).
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