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Butyrophilin, subfamily 3, member A2

BT3, BTN3A2
This gene encodes a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other six family members, including BTN, BTN2A1, BTN2A2, BTN2A3, BTN3A1, and BTN3A3, on chromosome 6. The full-length protein encoded by this gene is a type I membrane protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] (from NCBI)
Top mentioned proteins: Bt2, ACID, CAN, HAD, CD4
Papers on BT3
Gene Expression in HIV-Associated Neurocognitive Disorders: A Meta-Analysis.
New
Archer et al., Richmond, United States. In J Acquir Immune Defic Syndr, Jan 2016
Only BTN3A2 was expressed in HAND with HIVE patients as compared with HAND patients without HIVE.
Novel components of leaf bacterial communities of field-grown tomato plants and their potential for plant growth promotion and biocontrol of tomato diseases.
New
Pieckenstain et al., San Martín, Argentina. In Res Microbiol, Dec 2015
Analysis of 16S rRNA gene sequences identified bacterial isolates related to Exiguobacterium aurantiacum (isolates BT3 and MT8), Exiguobacterium spp.
Evolution of a chimeric aspartate kinase for L-lysine production using a synthetic RNA device.
New
Qi et al., Jinan, China. In Appl Microbiol Biotechnol, Oct 2015
Of three evolved aspartate kinases, the best mutant BT3 showed 160 % increased in vitro activity compared to the wild-type enzyme.
Fine-mapping butyrophilin family genes revealed several polymorphisms influencing viral genotype selection in hepatitis C infection.
New
Romero-Gómez et al., Sevilla, Spain. In Genes Immun, Jul 2015
In a preliminary GWAS analysis, we identified BTN3A2 rs9104 to be associated with HCV genotype 1.
Effects of benzoic Acid and thymol on growth performance and gut characteristics of weaned piglets.
New
Chen et al., China. In Asian-australas J Anim Sci, Jun 2015
Pigs were randomly allotted to 4 dietary treatments: i) control (C), basal diet, ii) C+1,000 mg/kg benzoic acid+100 mg/kg thymol (BT1), iii) C+1,000 mg/kg benzoic acid+200 mg/kg thymol (BT2) and, iv) C+2,000 mg/kg benzoic acid+100 mg/kg thymol (BT3).
Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.
New
Trowsdale et al., Cambridge, United Kingdom. In J Immunol, Apr 2015
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells.
Spectroscopic and electrical studies on Nd(3+), Zr(4+) ions doped nano-sized BaTiO3 ferroelectrics prepared by sol-gel method.
New
Prasad et al., Hyderābād, India. In Spectrochim Acta A Mol Biomol Spectrosc, Mar 2015
Lead free ferroelectric ceramics in the form of Ba(1-3x)Nd(2x)Ti(1-y)ZryO3 ((where x=0.025, y=0 (BT1), 0.025 (BT2), 0.05 (BT3)) were prepared using sol-gel method.
Engineering Delftia acidovorans DSM39 to produce polyhydroxyalkanoates from slaughterhouse waste.
Casella et al., Padova, Italy. In Int J Biol Macromol, 2014
The lipC and lipH genes of Pseudomonas stutzeri BT3, proficient lipolytic isolate, were successfully co-expressed into D. acidovorans DSM39 and the resulting recombinant strain displayed high extracellular enzymatic activity on corn oil.
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase.
Chuang et al., In J Biol Chem, 2014
N-(4-acetamido-1,2,5-oxadiazol-3-yl)-3,6-dichlorobenzo[ b]thiophene-2-carboxamide (BT3)) significantly increase residual BCKDC activity in cultured cells and primary hepatocytes from patients and a mouse model of maple syrup urine disease.
Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.
Santos et al., Salamanca, Spain. In Bmc Genomics, 2013
Reporter luciferase assays in BT3 insulinoma cells demonstrated the ability of RasGrf1 to modulate mPttg1 promoter activity through ERK-mediated signals.
Tunable electronic coupling and driving force in structurally well-defined tetracene dimers for molecular singlet fission: a computational exploration using density functional theory.
Damrauer et al., Boulder, United States. In J Phys Chem A, 2013
Although the electronic coupling of a series of C2v-symmetric dimers (BT1-BT3) that differ in norbornyl bridge length is larger than in previously studied Tc dimers, a key nonhorizontal electron-transfer (ET) matrix element used in determining the SF rate is zero due to symmetry.
Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells.
Morita et al., Iowa City, United States. In J Immunol, 2013
Importantly, small interfering RNA knockdown of BTN3A1 abolished stimulation by IPP that could be restored by re-expression of BTN3A1 but not by BTN3A2 or BTN3A3.
Genome Sequence of the Pathogenic Bacterium Vibrio vulnificus Biotype 3.
Kashi et al., Haifa, Israel. In Genome Announc, 2013
This draft genome sequence of the environmental strain VVyb1(BT3), isolated in Israel, provides a representation of this newly emerged clonal group, which reveals higher similarity to the clinical strains of biotype 1 than to the environmental ones.
Insight into the evolution of Vibrio vulnificus biotype 3's genome.
Kashi et al., Haifa, Israel. In Front Microbiol, 2012
To understand the evolution of the bacterium's genome, we sequenced and analyzed the genome of biotype 3 strain VVyb1(BT3), and then conducted a microbial environmental survey of the hypothesized niche from which it probably evolved.
Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex.
GeneRIF
Lie et al., Oslo, Norway. In Genes Immun, 2009
our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I Deabetes.
[Lymphocyte coreceptors].
Review
Olive, Marseille, France. In Med Sci (paris), 2006
Three other B7 family members B7-H3, B7-H4 and BT3.1 are orphan receptors until now.
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