A systematic review of genetic studies of thyroid disorders in Taiwan.
Taipei, Taiwan. In J Chin Med Assoc, 11 Dec 2014
The prevalence of various somatic mutations in differentiated thyroid cancer was similar in Taiwan and Western countries, with the RAS kinase mutation and tyrosine receptor kinase (TRK) and rearranged during transfection (RET) proto-oncogenes being detected in lower frequencies and the B-type RAF kinase (BRAF) mutation accounting for the majority of cases.
Targeted therapy: A new hope for thyroid carcinomas.
Napoli, Italy. In Crit Rev Oncol Hematol, 01 Dec 2014
RET/PTC mutations are often discovered both in papillary and in medullary carcinomas, while B-RAF mutation is typical of papillary and anaplastic histologies.
[Adverse Effects of Modern Treatment of Malignant Melanoma and their Treatment/ Management.]
In Klin Onkol, Dec 2013
This could contribute to a prompt management of associated symptoms or an early referral of the patient to an appropriate clinical centre without undue delay.Key words: melanoma - immunotherapy - targeted therapy - side effects - BRAF inhibitor - anti-CTLA-4 -anti-PD-1 - MEK inhibitor The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.